0000000000171458

AUTHOR

Benjamin F. Trump

showing 3 related works from this author

Third International Congress of Histochemistry and Cytochemistry

1968

The tissue distribution of enzymatic activities in intestinal metaplasia stomachs exhibiting chronic gastritis was compared histochemically with that of the small intestine in man.

0303 health sciencesPathologymedicine.medical_specialtybiology030302 biochemistry & molecular biologyAcridine orangeAcid phosphataseChronic gastritisIntestinal metaplasiamedicine.diseaseSmall intestine03 medical and health scienceschemistry.chemical_compoundmedicine.anatomical_structurechemistryInternational congressmedicineCytochemistrybiology.proteinImmunohistochemistry030304 developmental biology
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Studies on the subcellular pathophysiology of acute lethal cell injury.

1974

Summary In this paper we have summarized the effects of acute lethal injury on the cell. Such injuries are defined as injuries that result in cell death within a relatively short period of time usually minutes or hours. Following death; the cell undergoes necrosis. Ultrastructural and biochemical methods are needed to study pathophysiology. The cell passes through a series of stages numbered 1 through 7. Stages 1 through 4 are reversible while 5 through 7 are irreversible. Injuries resulting in acute cell death and necrosis include direct damage to the cell membrane, for example by antibody and complement or non-penetrating mercurials or interference with mitochondrial energy supply as in i…

Programmed cell deathPathologymedicine.medical_specialtyNecrosisTime FactorsCell SurvivalCellsCellIschemiaMitochondrionBiologyPermeabilityPathology and Forensic MedicineCell Physiological PhenomenaCell membraneKidney Tubules Proximal03 medical and health sciencesNecrosis0302 clinical medicineIschemiamedicineAnimalsHypoxia030304 developmental biology0303 health sciencesCell MembraneGeneral MedicineHypoxia (medical)medicine.diseasePathophysiology3. Good healthMitochondriaRatsMicroscopy Electronmedicine.anatomical_structuremedicine.symptomMitochondrial Swelling030217 neurology & neurosurgeryBeitrage zur Pathologie
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Studies on the subcellular pathophysiology of sublethal chronic cell injury.

1974

Summary This paper summarizes some of the important subcellular events occurring after chronic sublethal cell injury. Chronic cell injury is defined as the result of injurious stimuli which permit cell survival though in altered steady states for protracted periods of time. The importance of ultrastructural and biochemical studies of these phenomena is emphasized. Among the phenomena discussed are alterations in lysosomes, cellular hypertrophy, fatty metamorphosis, alterations in microfilaments and microtubules, alterations in mechanisms of transcription and replication, disturbances in the cell surface and transport across the cell membrane, and alterations in intracellular transport.

AdultMaleTime FactorsTranscription GeneticSurface PropertiesCellsCellGuinea PigsBronchiBiologyMicrofilamentMicrotubulesPathology and Forensic MedicineMuscle hypertrophyCell Physiological PhenomenaCell membraneMiceMicrotubuleTranscription (biology)medicineAnimalsHumansCerebral CortexMacrophagesMusclesCell MembraneBiological TransportGeneral MedicineHypertrophyMiddle AgedPathophysiologyCell biologyMicroscopy Electronmedicine.anatomical_structureLiverUltrastructureRabbitsLysosomesCell DivisionBeitrage zur Pathologie
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