0000000000177687
AUTHOR
Rainer Lippold
Quantitative ECG analysis for individual risk assessment of future myocardial infarct-results from the MARISK study
From 1980 to 1990 the authors performed an epidemiological cohort study in order to explore the predictive power of computer electrocardiogram (ECG) measurements for individual risk assessment of future myocardial infarct in combination with commonly known risk factors. Out of 7542 participants, 83 experienced a myocardial infarct during the course of the study. Multivariate logistic regression analysis revealed that vector cardiogram (VCG) measurements provide significant additional information to risk estimation which is equivalent to that of other risk factors. Measurement changes are stronger risk indicators than single measurements. The results confirm previous findings from H.V. Pipbe…
Prognostic Factors Determining Long-Term Survival in Well-Differentiated Thyroid Cancer: An Analysis of Four Hundred Eighty-Four Patients Undergoing Therapy and Aftercare at the Same Institution
Identification of the prognostic factors relevant for long-term survival in differentiated thyroid cancer in a homogenously treated patient cohort in order to allow a better initial risk stratification.Four hundred eighty-four (358 females/126 males) patients with differentiated thyroid cancer (330 papillary [68.2%]; 154 follicular [31.8%]) were included. Inclusion criteria consisted of treatment with a uniform therapy scheme and continuous aftercare in the same institution. Initial diagnosis was between 1975-1995 (age at diagnosis, 14-84 years, median, 49.7). Tumor stage: pT1, n = 92; pT2, 211; pT3, 58; pT4, 123. Low-risk:or=pT3 NX M0, 331; high-risk pT4 and/or M1, 153. After thyroidectomy…
Influence of nerve of origin and tumor size of vestibular schwannoma on dynamic posturography findings.
Condition 5-score (C5S) and vestibular ratio (VER) correlate, but condition-6-score (C6S) and mean overall balance score (MOBS) do not, with the size of an inferior vestibular nerve (IVN) vestibular schwannoma (VS). In IVN VS patients the visual system plays a major role in the maintenance of postural stability.To test whether the size of a superior vestibular nerve (SVN) or IVN VS, as measured on MRI scans, correlates with computerized dynamic platform posturography (CDPP) findings and whether CDPP findings could preoperatively predict the nerve of origin of the VS.This was a retrospective study. Seventy-five consecutive VS patients were evaluated. C5S, C6S, VER, and MOBS were evaluated. S…
The diagnostic significance of IgG cow's milk protein antibodies re-evaluated
The effect of different feeding regimens, notably the use of hydrolysed cow's milk formulas, on the development of allergic reactions and the development of cow's milk protein-IgG antibodies is still disputed. We prospectively compared the development of allergic manifestations and cow's milk protein-IgG antibodies in a total of 702 infants who were divided into six groups: Cow's milk protein antibodies were determined by an indirect immuno-fluorescent test. Antibody titres rose slowly in groups 1, 3 and 6. Children in group 5 showed two high peaks. There were no significant differences in the frequency and type of allergic manifestations between the groups. Introduction of cow's milk formu…
Polysomnography and ApneaGraph in patients with sleep-related breathing disorders.
<i>Purpose:</i> To evaluate whether ApneaGraph (AG) and polysomnography (PSG) deliver comparable results in patients with sleep-related breathing disorders. <i>Procedures:</i> A prospective study was performed, which included 14 patients with obstructive sleep apnea syndrome. Apnea-hypopnea index (AHI), hypopnea index (HI), apnea index (AI), obstructive, central and mixed apnea, oxygen saturation (SaO<sub>2</sub>), pulse and body position were simultaneously assessed by PSG and AG in each individual. <i>Results:</i> There was a good correlation between measurements of AG and PSG for AHI, pulse, SaO<sub>2</sub>, body position and ce…
IgG, IgA, and IgE Antibodies to Cow Milk Proteins in an Allergy Prevention Study
In the last few years, several trials have been carried out to determine if certain feeding regimens in neonates prevent atopic diseases1–13. In our country, there is a continuing debate about nutritional supplementation of breast milk with hydrolysate formulas: in the first days of life should only newborns at allergy risk8,9,11,14, or should all newborns be fed only breast milk? This age is claimed to be an especially vulnerable period for a sensitization against foreign proteins because of intestinal immaturity and inexperienced gut-associated lymphoid tissue15. A prospective Danish study revealed cases of cow’s milk allergy only among those breastfed infants who had received cow’s milk …