6533b871fe1ef96bd12d0e6e
RESEARCH PRODUCT
IgG, IgA, and IgE Antibodies to Cow Milk Proteins in an Allergy Prevention Study
Annemarie Bürgin-wolffRainer LippoldKlaus M. KellerHartmut MengerWalter BaumannStefan Wirthsubject
Allergybiologybusiness.industryfood and beveragesHypoallergenicMilk allergyBreast milkmedicine.diseaseImmunoglobulin Emedicine.anatomical_structureFood allergyImmunologymedicinebiology.proteinbusinessBreast feedingSensitizationdescription
In the last few years, several trials have been carried out to determine if certain feeding regimens in neonates prevent atopic diseases1–13. In our country, there is a continuing debate about nutritional supplementation of breast milk with hydrolysate formulas: in the first days of life should only newborns at allergy risk8,9,11,14, or should all newborns be fed only breast milk? This age is claimed to be an especially vulnerable period for a sensitization against foreign proteins because of intestinal immaturity and inexperienced gut-associated lymphoid tissue15. A prospective Danish study revealed cases of cow’s milk allergy only among those breastfed infants who had received cow’s milk formula as a “night-bottle”16. Others reported allergic manifestations in infants after a sensitization by small quantities of antigens via human milk17,18. The milk industries have provided pediatricians with several new “hypoallergenic” (HA) hydrolysate formulas of different origin and of different molecular size promising allergy prevention not only in newborns at risk.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1991-01-01 |