0000000000186325

AUTHOR

Heiner Wehrbein

showing 7 related works from this author

Plaque levels of patients with fixed orthodontic appliances measured by digital plaque image analysis

2011

Introduction A digital plaque image analysis system was developed to objectively assess dental plaque formation and coverage in patients treated with fixed orthodontic appliances. Methods The technique was used to assess plaque levels of 52 patients undergoing treatment with fixed appliances in the Department of Orthodontics at Johannes Gutenberg University in Mainz, Germany. Results Plaque levels ranged from 5.1% to 85.3% of the analyzed tooth areas. About 37% of the patients had plaque levels over 50% of the dentition, but only 10% exhibited plaque levels below 15% of tooth coverage. The mean plaque coverage was 41.9% ± 18.8%. Plaque was mostly present along the gum line and around the or…

MaleAdolescentOrthodontic BracketsSurface PropertiesDental PlaqueGingivaDentistryOrthodonticsOral hygieneImage Processing Computer-AssistedOrthodontic WiresPhotographyHumansMedicineIn patientChildFluorescent DyesOrthodonticsbusiness.industryReproducibility of ResultsOrthodontic bracketsDental plaque formationFemaleFluoresceinbusinessToothSoftwareAmerican Journal of Orthodontics and Dentofacial Orthopedics
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Osteogenic differentiation of periodontal fibroblasts is dependent on the strength of mechanical strain

2012

Abstract Objective During orthodontic therapy the correct strength of mechanical strain plays a key role for bone remodelling during tooth movement. Aim of this study was to investigate the osteogenic differentiation of human periodontal ligament fibroblasts (HPdLF) depending on the applied strength of mechanical strain compared to osteoblasts (HOB). Design HPdLF and HOB were loaded with different strengths (1%, 5% and 10%) of static mechanical strain (SMS) for 12 h in vitro. Viability was verified by MTT and apoptosis by TUNEL assay. Gene expression of cyclin D1, collagen type-1 (COL-I), alkaline phosphatase (ALP), osteocalcin, osteoprotegerin (OPG) and receptor activator of the NF-κB liga…

musculoskeletal diseasesCell SurvivalPeriodontal LigamentGene ExpressionDentistryApoptosisEnzyme-Linked Immunosorbent AssayReal-Time Polymerase Chain ReactionCollagen Type IBone remodelingAndrologyCyclin D1OsteoprotegerinOsteogenesisIn Situ Nick-End LabelingHumansPeriodontal fiberCyclin D1RNA MessengerGeneral DentistryCells CulturedAnalysis of VarianceOsteoblastsTUNEL assaybiologybusiness.industryChemistryRANK LigandOsteoprotegerinCell DifferentiationCell BiologyGeneral MedicineFibroblastsAlkaline PhosphataseOtorhinolaryngologyRANKLOsteocalcinbiology.proteinAlkaline phosphataseStress MechanicalbusinessArchives of Oral Biology
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Orthodontic load on short maxillary implants with reduced sink depth: an experimental study.

2008

Objective The aim of this study was to investigate experimentally the positional stability and histomorphometric findings of length-reduced temporary anchorage devices (Orthosystem, length: 4 mm) with reduced sink depth. Material and methods For this purpose, four maxillary pre-molars ((2)P(2), (3)P(3)) were extracted from each of four foxhounds. After a 16-week alveolar healing period, 16 implants (four per dog) were inserted into the edentulous areas. Four implants (one per dog) were placed simultaneously in the mid-palatal area. The implants were intentionally submerged to about three-quarters of their length. After a 10-week unloaded implant healing period, the implants in the P3 areas …

MaleImplant surfaceTime FactorsSurface PropertiesBone ScrewsDentistryBone contactDogsOrthodontic AppliancesBone MarrowOsseointegrationAlveolar ProcessMaxillaOrthodontic Anchorage ProceduresOrthodontic WiresMedicineAnimalsOrthodontic Appliance DesignBicuspidDental ImplantsOrthodontic wireOrthodontic Appliance Designbusiness.industryPalateBone screwsEquipment failureMaxillaEquipment FailureImplantBone RemodelingStress MechanicalOral SurgerybusinessClinical oral implants research
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Periodontal impact of surgically induced dental lesions in mandibular osteodistraction: An animal study.

2009

SUMMARY. Aim: The objective of the study was to evaluatethe impact of dental lesions on the periodontium, in a canine model of mandibular osteodistraction. Material and methods: In six adult male Beagle dogs, an osteotomy was made between the right second lateral incisor and canine, and a distraction device placed. The roots adjacent to the osteotomy were deliberately damaged by the reciprocating saw and chisel, with preservation of the attached gingiva. The osteodistraction protocol used was: latency of 7 days, rate of distraction 1 mm per day, and rhythm once a day for 5 days. Vital staining was carried out with tetracycline, Xylenol Orange and Calcein Green. The dogs were sacrificed afte…

MalePeriodontiumBone Regenerationmedicine.medical_treatmentMandíbulaOsteogenesis DistractionDentistryMandibleOsteotomyosteogenesisDogsstomatognathic systemPulp canalMedicinePeriodontal fiberRegenerationAnimalsOsteotomiaCementumTooth Rootanimal experimentationWound HealingRaiz Dentáriabusiness.industryAnimalPeriodontiumOsteogenese por DistraçãoOsteotomystomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyVital stainDistraction osteogenesisPulp (tooth)SurgeryOral SurgeryCicatrizaçãobusinessperiodontiumdistraction
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Mundhygiene und Ernährungsgewohnheiten bei Jugendlichen mit festsitzenden kieferorthopädischen Apparaturen

2012

Eine Vielzahl an Studien belegen, dass festsitzende kieferorthopadische Behandlungsmasnahmen (Multiband- oder Multibracket-Apparaturen) eine temporare Verschlechterung der Mundhygiene mit entsprechenden entzundlich bedingten Gingivaveranderungen hervorrufen konnen. Optimale Mundhygienemasnahmen und Anderungen der Ernahrungsgewohnheiten sind wesentliche Faktoren, um parodontale Entzundungen bei festsitzenden kieferorthopadischen (KFO-) Apparaturen zu vermeiden. In der vorliegenden Studie sollte uberpruft werden, inwieweit die Empfehlungen der behandelnden Kieferorthopaden von jugendlichen Patienten nachvollzogen werden. Insgesamt wurden 67 jugendliche Patienten mit festsitzenden KFO-Apparatu…

Gynecologymedicine.medical_specialtybusiness.industrymedicineGeneral MedicineDental hygienebusinessFixed orthodontic applianceZWR - Das Deutsche Zahnärzteblatt
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Development of a novel histological and histomorphometric evaluation protocol for a standardized description of the mid‐palatal suture – An ex vivo s…

2019

The hard palate and mid‐palatal suture are highly important for orthodontic treatment. In cases of transverse maxillary deficiency, palatal expansion is the treatment of choice. As nowadays a growing number of adult patients receive orthodontic treatment, an understanding of suture development throughout life is important to derive tailored orthodontic treatment techniques for each age group. Histological, histochemical and immunohistochemical stains (haematoxylin & eosin, Azan, Movat pentachrome, Masson–Goldner trichrome, Sirius Red, CD 31, osteopontin and TRAP) and histomorphometric analyses were re‐established to detect the structural conditions of the mid‐palatal suture in human cadaver…

AdultMalePalate Hard0301 basic medicineHistologyBone densityHaematoxylinYoung Adult03 medical and health scienceschemistry.chemical_compound0302 clinical medicineSuture (anatomy)TrichromeMaxillaMethodsmedicineHumansMolecular BiologySirius RedEcology Evolution Behavior and SystematicsAgedOrthodonticsbusiness.industryHistological TechniquesHistologyCranial SuturesCell BiologyMiddle AgedStaining030104 developmental biologymedicine.anatomical_structurechemistryFemaleHard palateAnatomybusiness030217 neurology & neurosurgeryDevelopmental BiologyJournal of Anatomy
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Interdisciplinary approach for the treatment of periodontally compromised malpositioned anterior teeth: a case report

2009

Today many adult patients with periodontal disease demonstrate positioning of teeth that comprise their ability for proper mechanical tooth cleaning of approximal tooth surfaces. With adequate combined periodontal-orthodontic treatment it is possible to re-establish a healthy and well-functioning dentition. However, while orthodontic treatment can realign periodontally affected teeth, esthetic appearance may be compromised by gingival recession due to alveolar bone dehiscences or fenestrations in combination with a thin gingival biotype. This article reports an interdisciplinary (periodontic, orthodontic, restorative) approach for the treatment of a periodontally compromised patient with an…

OrthodonticsMedicine(all)medicine.medical_specialtyDentitionbusiness.industryDentistryGeneral MedicinePlastic surgerystomatognathic diseasesPeriodontal diseasestomatognathic systemCase reportGingival biotypemedicineImplantmedicine.symptombusinessGingival recessionAnterior teethDental alveolusCases Journal
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