0000000000186557

AUTHOR

José Rafael Bretón-martínez

showing 6 related works from this author

Evaluation of a rapid antigen detection test (Panbio™ COVID‐19 Ag Rapid Test Device) as a point‐of‐care diagnostic tool for COVID‐19 in a pediatric e…

2021

Abstract We evaluated the Panbio™ COVID‐19 Ag Rapid Test Device as a point‐of‐care diagnostic tool for COVID‐19 in 357 patients at a pediatric emergency department. Thirty‐four patients tested positive by reverse transcription polymerase chain reaction, of which 24 were positive by the antigen assay. The sensitivity and specificity of the assay were 70.5% and 100%, respectively.

Pediatric emergencyMale2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)emergency departmentShort CommunicationShort CommunicationsSARS‐CoV‐2 RNA viral loadfield evaluationImmunologic TestsSensitivity and SpecificityCOVID-19 Serological TestingAntigenVirologyInternal medicineNasopharynxmedicineHumansProspective StudiesChildAntigens ViralPoint of carepediatric patientsbusiness.industrySARS-CoV-2clinical sensitivityCOVID-19InfantEmergency departmentVirologyTest (assessment)Reverse transcription polymerase chain reactionInfectious Diseasesrapid antigen assayPoint-of-Care TestingCOVID-19 Nucleic Acid TestingChild PreschoolFemalebusinessEmergency Service HospitalJournal of Medical Virology
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Community-acquired febrile urinary tract infection caused by extended-spectrum beta-lactamase-producing bacteria in hospitalised infants.

2015

Abstract Introduction Extended-spectrum beta-lactamase (ESBL) producing bacteria are infrequent pathogens of urinary tract infections in children. The objective of our study was to investigate the presence, clinically associated characteristics and risk factors for acquisition of urinary tract infection/acute pyelonephritis (UTI/APN) in hospitalised children Methods A case-control study in a second level community hospital in Spain, in which 537 episodes of UTI/APN were investigated in a retrospective study between November 2005 and August 2014. Cases were patients with ESBL strains. For each case, four ESBL-negative controls were selected. A questionnaire with the variables of interest was…

0301 basic medicineMalemedicine.medical_specialtyFevermedicine.drug_classmedicine.medical_treatment030106 microbiologyAntibioticsHospitals CommunityComorbidityFosfomycinTazobactamVesicoureteral refluxMeropenembeta-Lactam Resistancebeta-Lactamases03 medical and health sciencesBacterial ProteinsRisk FactorsInternal medicineSurveys and Questionnairespolycyclic compoundsmedicineEscherichia coliHumansEscherichia coli InfectionsRetrospective StudiesVesico-Ureteral RefluxInpatientsPyelonephritisbusiness.industryInfantbiochemical phenomena metabolism and nutritionbacterial infections and mycosesmedicine.diseaseSurgeryCommunity-Acquired InfectionsSpainCase-Control StudiesUrinary Tract InfectionsBeta-lactamasebacteriaGentamicinFemalebusinessmedicine.drugPiperacillinEnfermedades infecciosas y microbiologia clinica
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Case Report: Primary Peritonitis as the Onset of Pediatric Ménétriers Disease

2021

Introduction: Primary peritonitis (PP) and Ménétrier's Disease (MD) are both rare conditions among pediatric population. Although about 150 MD cases have been described in the scientific literature to date, its onset with a PP is an unusual condition.Case Presentation: We present a case of an 11-year-old boy who was admitted to our unit because of abdominal pain and distension. Complementary tests showed ascites, bilateral pleural effusion, leukocytosis, increased acute phase reactants and hypoproteinemia with hypoalbuminemia. Laparoscopy ruled out appendicitis or visceral perforations and exposed purulent peritoneal fluid, compatible with PP. Biochemical stool analysis showed increased cle…

Abdominal painmedicine.medical_specialtyPediatricsGastroenterology03 medical and health sciencesHypoproteinemia0302 clinical medicine030225 pediatricsInternal medicineMénétrier's diseaseAscitesmedicinecase reportEnteropathyHypoalbuminemiaprotein-losing enteropathybusiness.industryProtein losing enteropathylcsh:RJ1-570lcsh:Pediatricsmedicine.diseaseAppendicitisMénétrier's diseasehypertrophic gastropathyPediatrics Perinatology and Child Health030211 gastroenterology & hepatologymedicine.symptombusinessprimary peritonitisFrontiers in Pediatrics
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Non-wild-type cryptococcosis in a child with multivisceral organ transplant who owned bird pets.

2020

Cryptococcosis is the third most common invasive fungal infection in solid-organ transplant recipients, although it is rarely reported in transplanted children. It typically appears as a late-onset infection with central nervous system or pulmonary involvement. We present a case of cryptococcosis caused by a non-wild strain in a 10-year-old child who owned two pet birds, and review the existent literature.

medicine.medical_specialtyAntifungal AgentsCentral nervous systemDrug resistance030230 surgeryOrgan transplantationBirds03 medical and health sciences0302 clinical medicinemedicineAnimalsHumansChildCryptococcus neoformansTransplantationNon wild typebiologybusiness.industryCryptococcosisOrgan TransplantationPetsbiology.organism_classificationmedicine.diseaseInfectious Diseasesmedicine.anatomical_structureImmunologyCryptococcosisCryptococcus neoformans030211 gastroenterology & hepatologySolid organ transplantationbusinessTransplant infectious disease : an official journal of the Transplantation SocietyREFERENCES
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Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults

2021

ABSTRACTObjectivesThere is limited information comparing SARS-CoV-2 RNA load in the upper respiratory tract (URT) between children and adults, either presenting with COVID-19 or asymptomatic. Here we conducted a retrospective, single center study involving a large cohort of SARS-CoV-2 infected individuals to address this issue.Patients and MethodsA total of 1,184 consecutive subjects (256 children and 928 adults) testing positive for SARS-COV-2 RNA in nasopharyngeal exudates (NP) were included, of whom 424 (121 children and 303 adults) had COVID-19 not requiring hospitalization and 760 (135 children and 625 adults) were asymptomatic close contacts of COVID-19 patients. SARS-CoV-2 RNA testin…

AdultMicrobiology (medical)medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationSingle CenterAsymptomaticGastroenterologychildrenNasopharynxInternal medicinemedicineSingle specimenAdultsHumansViral sheddingChildeducationAsymptomatic InfectionsRetrospective Studieseducation.field_of_studySARS-CoV-2business.industryCOVID-19RNAGeneral MedicineViral LoadSARS-CoV-2 RNALarge cohortInfectious Diseasesmedicine.anatomical_structureRNA ViralOriginal Articlemedicine.symptombusinessViral loadUpper respiratory tractRespiratory tractClinical Microbiology and Infection
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Infección urinaria febril adquirida en la comunidad por bacterias productoras de betalactamasas de espectro extendido en niños hospitalizados

2017

Resumen Introduccion El objetivo de nuestro estudio fue investigar la presencia, las caracteristicas clinicas y los factores de riesgo para la adquisicion de infeccion urinaria febril/pielonefritis (ITU/PNA) de la comunidad por microorganismos productores de betalactamasas de espectro extendido (BLEE+) en ninos Metodos Estudio de casos-controles en un hospital de segundo nivel en Espana. Se revisaron de forma retrospectiva 537 episodios de ITU/PNA entre noviembre de 2005 y agosto de 2014. Los casos fueron las ITU/PNA BLEE+. Por cada caso se escogieron 4 controles betalactamasas de espectro extendido negativos (BLEE−). Para cada paciente se relleno un cuestionario con las variables de intere…

0301 basic medicineMicrobiology (medical)03 medical and health sciences030106 microbiologyEnfermedades Infecciosas y Microbiología Clínica
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