0000000000190093

AUTHOR

Rosana Andrea Morelatto

showing 2 related works from this author

Nitric oxide synthase 2 (NOS2) expression in histologically normal margins of oral squamous cell carcinoma

2014

The activity of Nitric Oxide Synthase 2 (NOS2) was found in oral squamous cell carcinomas (OSCC) but not in normal mucosa. Molecular changes associated to early carcinogenesis have been found in mucosa near carcinomas, which is considered a model to study field cancerization. The aim of the present study is to analyze NOS2 expression at the histologically normal margins of OSCC. Study Design: Eleven biopsy specimens of OSCC containing histologically normal margins (HNM) were analyzed. Ten biopsies of normal oral mucosa were used as controls. The activity of NOS2 was determined by immunohistochemistry. Salivary nitrate and nitrite as well as tobacco and alcohol consumption were also analyzed…

MalePathologyNitric Oxide Synthase Type IImedicine.disease_causechemistry.chemical_compoundField cancerizationMedicineNitriteMouth neoplasmAged 80 and overbiologymedicine.diagnostic_testCarcinoma oral de células escamosasNitric oxide synthase 2Patología//purl.org/becyt/ford/3.1 [https]Middle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludMedicina BásicaOral squamous cell carcinomaUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellImmunohistochemistryFemaleMouth Neoplasms//purl.org/becyt/ford/3 [https]Adultmedicine.medical_specialtyCIENCIAS MÉDICAS Y DE LA SALUDOdontologíaBiopsyparasitic diseasesCarcinomaHumansNitric Oxide Synthase 2 (NOS2)Cancerización de campoGeneral DentistryAgedMarcadores de malignidadOral Medicine and Pathologybusiness.industryResearchmedicine.diseasestomatognathic diseasesCross-Sectional StudiesOtorhinolaryngologychemistrybiology.proteinSurgeryField cancerizationbusinessCarcinogenesisMalignity markers
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Oral Human Papillomavirus : a multisite infection

2020

Background The Human Papillomavirus (HPV) has different strategies for persist in the cells. This characteristic has led us to consider the presence of the virus in tissues of the oral cavity that had no clinical signs of infection. The aim of this study was to detect the presence of DNA-HPV at multiple sites of the oral cavity. Material and Methods A case-control study was designed: Oral Squamous Carcinoma Group (OSCG), healthy n=72 and Control Group (CG), n=72, healthy volunteers paired by sex and age with OSCG. Four samples were taken from OSCG: saliva, biopsy, brush scraping of lesion and contralateral healthy side. In CG a saliva sample and a scratch of the posterior border of tongue w…

Salivamedicine.medical_specialtyGastroenterologyLesion03 medical and health sciences0302 clinical medicineTongueInternal medicineBiopsymedicineHumansPapillomaviridaePapillomaviridaeGeneral DentistryMouth neoplasmOral Medicine and Pathologybiologymedicine.diagnostic_testbusiness.industryResearchPapillomavirus InfectionsCase-control study030206 dentistrybiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]Squamous carcinomastomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyCase-Control StudiesDNA ViralUNESCO::CIENCIAS MÉDICASMouth NeoplasmsSurgerymedicine.symptombusiness
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