0000000000195345
AUTHOR
Tiia Ngandu
Association between mid- to late life physical fitness and dementia: Evidence from the CAIDE study
Objectives. This study investigated the association between perceived physical fitness at midlife, changes in perceived fitness during the three decades from mid-to late life and dementia risk. Design. Prospective cohort study. Setting. Cardiovascular risk factors, ageing and incidence of dementia (CAIDE) study. Subjects. Subjects were selected from four independent, random samples of population-based cardiovascular surveys and were first examined in 1972, 1977, 1982 or 1987, when they were on average 50 years old. The CAIDE target population included 3559 individuals. A random sample of 2000 individuals still alive in 1997 was drawn for re-examinations (performed in 1998 and 2005-2008) tha…
Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia
Abstract Background Physical activity may be beneficial for cognition, but the effect may vary depending on personal characteristics. Methods We investigated the associations between leisure-time physical activity (LTPA) from mid- to late life, the risk of dementia, and the role of body mass index, sex, and APOE in the CAIDE study during 28-year follow-up. Cognitive function of a random subsample was assessed at a mean age of 78.8 years (n = 1511), and dementia/Alzheimer's disease (AD) diagnoses were identified from national registers for the entire target population (n = 3559). Results Moderate (hazard ratio [HR], 1.46; 95% confidence interval [CI], 1.08–1.99) and low levels of midlife LTP…
Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic—A Qualitative Study
The COVID-19 pandemic and its related restrictions have affected the everyday life of older people. Advanced age is a significant predisposing factor for a more severe COVID-19 infection, increasing the risk for hospitalization and mortality. Even though restrictions have been, thus, well-grounded, they may also have had detrimental effects on the social well-being of older people. Personal networks and social activity are known protective factors against the premature decline in health and functioning, and it is widely acknowledged that social isolation increases feelings of loneliness, poor quality of life, and even the risk for diseases and disabilities among older adults. This qualitati…
How can dementia and disability be prevented in older adults: where are we today and where are we going?
Abstract Ageing of the population, together with population growth, has brought along an ample increase in the number of older individuals living with dementia and disabilities. Dementia is the main cause of disability in old age, and promoting healthy brain ageing is considered as a key element in diminishing the burden of age‐related disabilities. The World Health Organization recently launched the first risk reduction guidelines for cognitive impairment and dementia. According to recent estimates, approximately 40% of dementia cases worldwide could be attributable to 12 modifiable risk factors: low education; midlife hypertension and obesity; diabetes, smoking, excessive alcohol use, phy…
P2‐310: MIDLIFE SELF‐RATED HEALTH AND FITNESS IN RELATION TO WHITE MATTER LESIONS AND GREY MATTER VOLUME 20 YEARS LATER
Midlife self-rated health and fitness in relation to white matter lesions and grey matter volume 20 years later
Liikkumisen kannustimet muistisairauksien riskiryhmään kuuluvilla ikääntyneillä
Liikunnallisesti aktiivinen elämäntapa ylläpitää tehokkaasti ikääntyneiden terveyttä ja toimintakykyä. Liikunnan harrastamiseen vaikuttavat kuitenkin monet yksilölliset tekijät, jotka tulisi huomioida kannustettaessa ikääntyneitä henkilöitä liikkumaan. Tämän tutkimuksen tarkoituksena oli selvittää, minkälaiset liikkumisen kannustimet ovat yhteydessä aktiiviseen liikunnan harrastamiseen ikääntyneillä ihmisillä, joilla riski muistisairauteen sairastumiseen on kohonnut. Tämä poikkileikkaustutkimus on osa laajempaa FINGER-tutkimusta (Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability), johon osallistui 1 260 keski-iältään 69-vuotiasta henkilöä. Tutkittavien fyys…