Food web reconstruction gives evidence of increased trophic levels in no-trawl areas: the red mullet, Mullus barbatus L. case in northern Sicily

This study was aimed at identifying the food web of the red mullet, Mullus barbatus in order to understand how it is affected by trawling disturbance. To achieve this objective: a) the main features of the red mullet habitat were investigated; b) the food web of this habitat was studied in two no-trawl areas and in two areas open to trawling. The working hypothesis is that trawling affects the biochemistry of the sediment and the trophic structure of the benthic assemblage. It was predicted: a) less biomass, smaller size and higher production rate in the benthic assemblages of protected gulfs; b) higher average trophic level for both the red mullet and its predators in protected gulfs; c) a…

An unusual presentation of T-lymphoma in a Crohn's 4 disease patient treated with combo therapy: We are 5 willing to take a risk of serious adverse events for a 6 doubtful benefit?

Effect of cold storage on the quality of minimally processed cauliflower

Cauliflower has been described as a vegetable with a high nutritional value due to its important content of vitamins, antioxidants and anti-carcinogenic compounds. Cauliflower inflorescences are harvested while they are totally immature, which implies severe changes in nutrient, water and hormonal status. Harvesting and the following processing can cause a severe stress determining the appearance of accelerated senescence symptoms. The effects of processing and cold storage of minimally processed green cauliflower were investigated. Florets were treated with antioxidants before storage in PE bags at 4°C for 21 days. During storage, weight loss, colour, firmness, soluble solids content and p…

The new Lessepsian entry Brachidontes pharaonis (Fischer P., 1870) (Bivalvia, Mytilidae) in the western Mediterranean: A physiological analysis under varying natural conditions

The feeding behavior of Brachidontes pharaonis (Mollusca, Bivalvia), a new Lessepsian entry in the western Mediterranean, living in a cooling vat of a saltworks system in western Sicily, was assessed by estimating its physiological rates throughout a 6 month-long study (May 1998 to March 1999). Clearance, filtration, ingestion, and food absorption rates were estimated using the biodeposition method and the results correlated to variations in temperature, salinity, and quality and quantity of available food. Measured seston concentrations were on average 81.5 ± 95.5 mg L-1, its labile fraction (estimated as the sum of particulate lipids, carbohydrates and proteins) was on average 0.55 ± 0.07…

INTEGRATED CALCAREOUS PLANKTON BIOSTRATIGRAPHY OF SELECTED MIOCENE SUCCESSIONS IN THE NORTHERN CALABRIA (ITALY).

An integrated calcareous plankton biostratigraphic approach on six sections cropping out in Northern Calabria allowed to define a revised chronostratigraphic framework for Tortonian-Messinian deposits. Four sections have been investigated in the Amantea Basin (Timpone Napoli, Vallone Salina, Case Vespano, and Cozzo Salice) and two in the Rossano Basin (Vallone Casino and Cozzo Sant'Isidoro). Biostratigraphic analyses have been based on quantitative counting of planktonic foraminifers and semiquantitative counting of nannofossils. The Timpone Napoli and Vallone Salina sections are Late Tortonian in age and referable to the Globorotalia suterae Zone. In terms of nannofossils zonal scheme thes…

COVER CROPS E INNESTO ERBACEO: TECNICHE ECOCOMPATIBILI IN SISTEMI ORTICOLI INTENSIVI

Multiplex PCR-Based Next-Generation Sequencing Approach Has Detected a Common Large Deletion in STS Gene in a Patient with X-Linked Ichthyosis

Several nuclear genes have been found to be linked to ichthyosis, and Next Generation Sequencing approach on panels of targeted genes has turned out to be particularly useful in analyzing diseases characterized by significant genetic and phenotypic heterogeneity. We developed a panel of 26 genes to be screened with the Ion Personal Genome Machine (PGM) for causative mutations relating to ichthyosis. Sequencing runs were obtained from a patient with ichthyosis using the Ion Torrent PGM and then processed with Ion Torrent Suite, Variant Caller, Coverage Analysis and wANNOVER tools. No causative mutations were found using Variant Caller and wANNOVER softwares, whereas the “Coverage Analysis” t…

The sicilian network for inflammatory bowel disease (SN-IBD): preliminary data on efficacy of biological therapy.

Introduction: The monitoring of appropriateness, costs, and clinical outcomes of biological therapy in inflammatory bowel disease (IBD) is a relevant need. Aims & Methods: We aimed to evaluate all these issues in Sicily through a webbased network of all prescribing centers. The Sicilian Network for Inflammatory Bowel Disease (SN-IBD) is composed by a super Hub coordinator centre and five Hub plus ten Spoke centres. From January 2013, all IBD patients starting a biological agent (incident cases) or already on treatment (prevalent cases) were entered in a web based software. Herein we report data of incident cases about the efficacy of biological therapy after twelve weeks and one year of…

Carciofo, nuovi orientamenti su produzione e coltivazione.

Analisi MLPA del gene CREB-binding protein (CREBBP) in un paziente con la sindrome di Rubinstein Taybi

La sindrome di Rubinstein-Taybi è una rara malattia congenita autosomica dominante caratterizzata da ritardo della crescita postnatale, ritardo dello sviluppo psicomotorio, anomalie scheletriche, peculiare morfologia facciale ed un aumento del rischio oncogeno. La prevalenza alla nascita è 1 su 125.000 nati vivi. La malattia può essere associata a mutazioni nel gene che codifica per la proteina CREB-binding localizzato nella regione cromosomica 16p13.3. Recenti studi hanno dimostrato che pazienti con quoziente intellettivo basso e tratti autistici possono avere grandi delezioni. Sulla base di queste osservazioni, abbiamo usato la Multiplex Ligation-dependent Probe Amplification (MLPA) per r…

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous studies; however, a large portion of the genetic risk for this disease remains unexplained. We conducted a large, two-stage meta-analysis of genome-wide association studies (GWAS) in individuals of European ancestry. In stage 1, we used genotyped and imputed data (7,055,881 SNPs) to perform meta-analysis on 4 previously published GWAS data sets consisting of 17,008 Alzheimer's disease cases and 37,154 controls. In stage 2, 11,632 SNPs were genotyped and tested for association in an independent set of 8,572 Alzheimer's disease cases and 11,312 controls. In addition to the APOE locu…