0000000000202146
AUTHOR
Geoffrey Gregis
showing 3 related works from this author
Detection of lung cancer bio-markers in human breath using a micro-fabricated air analyzer
2015
International audience; The analysis of volatile organic compounds (VOCs) that are linked to lung cancer is a very promising way in medical diagnostics because it is non-invasive and potentially inexpensive. In that sense, a silicon micro-analytical platform consisting of a three-dimensional micro-preconcentrator coupled to a silicon spiral gas chromatographic micro-column was built. A metal oxide-based gas sensor acted as a miniaturized gas detector. This system allowed selective detection of VOCs at the sub-ppm level. The present study is focused first on the chromatographic air analyzer fabrication and second on the selection of an appropriate adsorbent. Various adsorbents such as activa…
Characterization of materials toward toluene traces detection for air quality monitoring and lung cancer diagnosis
2017
International audience; The aim of this work was to identify a nanoporous material able to trap toluene traces in order to develop a gas detection device for indoor air quality monitoring or biomedical diagnosis. A set of various adsorbents such as zeolites and activated carbon microspheres was studied here. First a detailed characterization of their porous properties was performed by nitrogen adsorption. Then adsorption of toluene and other interfering compounds which can selectively adsorbed with it, such as water and carbon dioxide, was studied in order to select the most suitable material. Results revealed that the activatedcarbon microspheres W5 and the zeolite NaY, which exhibit high …
Detection and quantification of lung cancer biomarkers by a micro-analytical device using a single metal oxide-based gas sensor
2018
International audience; The analysis of exhaled volatile organic compounds (VOCs) related to lung cancer is a very promising wayin medical diagnosis because it is non-invasive and much less expensive than traditional medical analysisused so far. In that sense, a silicon micro-analytical platform consisting of a micro-preconcentrator cou-pled to a silicon spiral gas chromatographic micro-column was built, and a metal oxide-based gas sensorwas used as a miniaturized gas detector. This micro-fabricated device was successfully tested to selec-tively detect low concentrations of VOCs considered as lung cancer biomarkers, within a few minuteseven in presence of high concentrations of water vapor …