0000000000204997

AUTHOR

P. Pumpens

Self — Assembled System: Semiconductor and Virus Like Particles

Virus like nanoparticles (VLP) are in use to be absorbed by cells to cause biological effects. To increase a local concentration of VLP, nanoparticles-carriers bringing the latter to the target cell could be employed. N-type and p-type Si semiconductor nanoparticles, to control adhesion of VLP were applied. Optical absorbance spectra and electron microscopy evidenced that VLP became connected to Si nanoparticles. Moreover, a density of the adhered VLP depended on the type of both semiconductor and VLP.

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Self-Assembled System of Semiconductor and Virus Like Nanoparticles

Virus like nanoparticles (VLP) are in use to be absorbed by cells to cause biological effects. To increase a local concentration of VLP, nanoparticles-carriers bringing the latter to the target cell could be employed. N-type and p-type Si semiconductor nanoparticles, to control adhesion of VLP were applied. Optical absorbance spectra and electron microscopy evidenced that VLP became connected to Si nanoparticles. Moreover, a density of the adhered VLP depended on the type of both semiconductor and VLP.

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Inorganic Nanoparticle as a Carrier for Hepatitis B Viral Capsids

Virus like particles (VLP) are used to transport immune response-modulating agents to target cells to treat them. In order to deliver a high concentration of VLP to the cell, a number of VLP can be attached to a nanoparticle to be used as a nanolorry. In this study, SiO2 nanoparticles were attached to Hepatitis B VLP. Spectrophotometry measurements, electron, and fluorescent microscopy evidence showed that the SiO2 – Hepatitis B VLP complexes were formed.

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