6533b835fe1ef96bd129fd9a

RESEARCH PRODUCT

Inorganic Nanoparticle as a Carrier for Hepatitis B Viral Capsids

P. PumpensAloizijs PatmalnieksYu. DekhtyarAnna KachanovskaRegīna ReinhofaDace SkrastiņaMarina Romanova

subject

Chemistryvirusesvirus diseasesNanoparticleHepatitis Bmedicine.diseasecomplex mixturesVirologyVirusImmune systemCapsidSio2 nanoparticlesmedicineFluorescence microscopeHepatitis b viral

description

Virus like particles (VLP) are used to transport immune response-modulating agents to target cells to treat them. In order to deliver a high concentration of VLP to the cell, a number of VLP can be attached to a nanoparticle to be used as a nanolorry. In this study, SiO2 nanoparticles were attached to Hepatitis B VLP. Spectrophotometry measurements, electron, and fluorescent microscopy evidence showed that the SiO2 – Hepatitis B VLP complexes were formed.

yearjournalcountryeditionlanguage
2011-11-25
https://doi.org/10.1007/978-94-007-2488-4_23