0000000000217201
AUTHOR
Christian Tavernier
showing 5 related works from this author
Expression of the multidrug resistance glycoprotein 170 in the peripheral blood lymphocytes of rheumatoid arthritis patients. The percentage of lymph…
1996
International audience; Abstract: The objective was to evaluate the expression of the multidrug resistance P-glycoprotein (P-gp) in peripheral blood lymphocytes (PBL) of patients with rheumatoid arthritis (RA). PBL from 68 RA patients and 44 controls were evaluated. RA patients had a mean disease duration of 10.7 yr, with a mean number of past resistances to DMARDs of 0.82, and were treated with NSAIDs (n = 34), DMARDs (n = 25) and prednisolone (n = 40). Fluorescence flow cytometry was used to assess P-gp membrane expression on PBL. In the RA group, the percentage of PBL expressing P-gp was higher in patients treated with prednisolone than in other patients [mean +/- S.D.: 10.7 +/- 15.8% vs…
Effects of loss of metatarsophalangeal joint mobility on gait in rheumatoid arthritis patients
2005
Objective. To evaluate the effects of loss of range of motion (ROM) of the metatarsophalangeal (MTP) joint on the kinematic parameters of walking in rheumatoid arthritis (RA) patients. Methods. Inclusion of RA patients with inactive disease, no synovitis of the inferior limb and reduced ROM of the MTP joints. Evaluation of the ROM of the MTP dorsal and plantar flexion, and gait analysis using a three-dimensional computerized movement analysis. Calculation of gait parameters and maximal flexion and extension of the hips and knees during walking. Analysis 1 compared the ROM of dorsal and plantar flexion in patients with or without walking pain; 2 compared the gait parameters between patients …
Infections sévères à pyogènes chez les patients traités par infliximab. Étude d’une cohorte régionale
2005
Resume Objectif. – Apprecier la prevalence des infections severes a pyogenes chez les patients traites par infliximab en pratique courante, et essayer de degager des facteurs favorisants. Methodes. – Etude portant sur une cohorte de patients traites dans un reseau regional par infliximab pour polyarthrite rhumatoide ou spondylarthrite ankylosante, et suivis de facon prospective a l’aide d’une feuille de recueil des donnees standardisee. Les observations des patients ayant presente une infection grave a pyogene ont ete analysees, et comparees a celles des autres patients. Resultats. – La cohorte comportait 83 patients (55 femmes et 28 hommes), dont cinq (6 %) ont presente une infection sever…
Usefulness of routine hepatitis C and hepatitis B serology in the diagnosis of recent-onset arthritis. Systematic prospective screening in all patien…
2012
Ansemant, Thiphaine | Ornetti, Paul | Garrot, Jean-Francois | Pascaud, Francoise | Tavernier, Christian | Maillefert, Jean-Francis; International audience; ''Objective: Previous studies evaluating the usefulness of systematic screening for hepatitis B and C in patients with recent-onset arthritis suffered from a major bias since they were conducted in hospitals. The objective of the present study was to evaluate the relevance of such screening, performed by hospital and office-based rheumatologists of a defined area, in the diagnosis of arthritis or inflammatory polyarthralgia of less than 1 year duration. Methods: The CRRRI is a network which includes most hospital and office-based rheumat…
Intérêt du dépistage systématique des hépatites B et C à visée diagnostique dans le bilan initial des rhumatismes inflammatoires débutants
2012
Resume Objectif Les etudes realisees a ce jour pour evaluer l’interet d’un depistage systematique de l’hepatite B et C en cas d’arthrite d’installation recente souffrent toutes d’un biais methodologique important lie au recrutement hospitalier des malades. L’objectif de la presente etude consistait a evaluer la pertinence d’un tel depistage realise par les rhumatologues hospitaliers et liberaux d’une region geographique predefinie pour le diagnostic etiologique des arthrites et polyarthralgies inflammatoires datant de moins d’un an. Methodes Le CRRRI est un reseau qui rassemble la plupart des rhumatologues hospitaliers et liberaux d’une region de 506 755 habitants. Nous avons inclus tous le…