0000000000218216
AUTHOR
M. Ferraro
Carotid plaque detection improves the predictve value of CHA2DS2-VASc score in patients with non-valvular atrial fibrilation: The ARAPACIS Study
Abstract Background and aims Vascular disease (VD), as assessed by history of myocardial infarction or peripheral artery disease or aortic plaque, increases stroke risk in atrial fibrillation (AF), and is a component of risk assessment using the CHA 2 DS 2 -VASc score. We investigated if systemic atherosclerosis as detected by ultrasound carotid plaque (CP) could improve the predictive value of the CHA 2 DS 2 -VASc score. Methods We analysed data from the ARAPACIS study, an observational study including 2027 Italian patients with non-valvular AF, in whom CP was detected using Doppler Ultrasonography. Results VD was reported in 351 (17.3%) patients while CP was detected in 16.6% patients. Ad…
β₂ long-acting and anticholinergic drugs control TGF-β1-mediated neutrophilic inflammation in COPD.
Micromaterials lipid-based for topic release of fluticasone propionate for the COPD treatment
The importance of HCV on the burden of chronic liver disease in Italy: a multicenter prevalence study of 9,997 cases
Knowledge of the current epidemiology of chronic liver disease in Italy is mostly obsolete and fragmentary for the lack of up-to-date consistent data. In 2001, a 6-month prevalence study was undertaken in 79 hospitals to assess the characteristics of chronic liver disease in Italy. Both prevalent and incident cases were enrolled. A total of 9,997 patients were recruited, of whom 939 (9.4%) had normal liver biochemistry, 6,210 (62.1%) had chronic hepatitis, 1,940 (19.4%) had liver cirrhosis, and 341 (3.4%) had hepatocellular carcinoma (HCC). In 567 patients (5.7%) the diagnosis was not established. Hepatitis C virus (HCV) was found in 69.9% of the patients and was the only etiological factor…
Enhanced pulmonary delivery of Salmeterol Xinafoate (SX) by mucoadhesive microparticles
Evaluating fish assemblages associated with gas platforms: Evidence from a visual census technique and experimental fishing surveys
Fish assemblages associated with extractive platforms were surveyed, for the first time, using traditional fishing surveys (bottom gill net) and an underwater visual census (UVC) technique in order to test the effectiveness and to identify strengths and weaknesses of both methods. The study was carried out during three seasons at two offshore gas platforms (Eleonora and Squalo C) located in the central Adriatic Sea. Both methods recorded a similar number of fish species although with only eight species in common, thus supplying complementary information and a good estimate of the total fish species richness (39) associated with these gas platforms. The use of innovative techniques, such as …
Cellule staminali ematopoietiche circolanti come marker indipendente di buon outcome clinico in pazienti con beta talassemia
The aetiology of chronic hepatitis in Italy: results from a multicentre national study
Background: No recent national-level data on the aetiology of chronic hepatitis are available in Italy. Aim: To evaluate the current aetiology of chronic hepatitis in Italy. Patients: A total of 6210 chronic hepatitis patients (both prevalence and incident cases) consecutively admitted to 79 hospitals located throughout Italy were enrolled over a 6-month period in 2001. The hospitals were randomly selected through systematic cluster sampling. Results: The main agent associated with chronic hepatitis was hepatitis C virus, which was found in 76.5% of the patients (in 62.6% it was the only aetiologic factor). Hepatitis B surface antigen was present in the serum of 12.2% of the cases (in 9.2% …
Major adverse cardiovascular events in non-valvular atrial fibrillation with chronic obstructive pulmonary disease: the ARAPACIS study
Chronic obstructive pulmonary disease (COPD) increases the risk of mortality in non-valvular atrial fibrillation (NVAF) patients. Data on the relationship of COPD to major cardiovascular events (MACE) in AF have not been defined. The aim of the study is to assess the predictive value of COPD on incident MACE in NVAF patients over a 3-year follow-up. In the Atrial Fibrillation Registry for Ankle-Brachial Index Prevalence Assessment-Collaborative Italian Study (ARAPACIS) cohort, we evaluate the impact of COPD on the following clinical endpoints: MACE (including vascular death, fatal/non-fatal MI and stroke/TIA), cardiovascular (CV) death and all-cause mortality. Among 2027 NVAF patients, pati…
Integrazione della LCA nella simulazione termofisica degli edifici: un’applicazione in ambiente TRNSYS
I sistemi “edificio-impianto” di nuova costruzione, caratterizzati da migliori prestazioni energetiche, stanno riducendo sensibilmente gli impatti energetico-ambientali connessi alla loro fase d’uso. Per quantificare i costi energetici ed ambientali necessari ad ottenere tali prestazioni è necessario l’utilizzo di un approccio integrato alla progettazione, che coinvolga sia una simulazione termofisica della fase d’uso, che uno studio di Life Cycle Assessment (LCA) applicato all’intero ciclo di vita dell’edificio. L’articolo presenta un componente informatico innovativo integrato in ambiente TRNSYS che permette di integrare uno studio LCA di un edificio alla simulazione termofisica, in accor…
Factors affecting fish assemblages associated with gas platforms in the Mediterranean Sea
Abstract Understanding the role played by offshore platforms in marine ecosystems is acquiring increasing importance worldwide. In this work, underwater visual census techniques were applied to describe spatial and temporal patterns of fish assemblages associated with extractive platforms. Data were collected during three seasons according to the following spatial factors: Location (Adriatic and Ionian Seas), Depth (0–6 m and 12–18 m) and Distance from the platform (external and internal). Both univariate and multivariate analyses showed highly significant differences for each factor assessed in this study, as well as for the interaction among said factors. Results indicated that artificial…
HCV infection is a risk factor for gallstone disease in liver cirrhosis: an Italian epidemiological survey
We assessed the prevalence of gallbladder disease (i.e. gallstones plus cholecystectomy) among patients with liver disease and its association with the severity and aetiology of hepatic injury. Subjects, referred to 79 Italian hospitals, were enrolled in a 6-month period. The independent effect of the severity and aetiology of liver disease on gallstone disease prevalence was assessed by multiple logistic regression analysis. Overall, 4867 subjects tested anti-hepatitis C virus (HCV) positive alone, 839 were hepatitis B virus surface antigen (HBsAg) alone, and 652 had an excessive alcohol intake. The prevalence of gallstone disease was 23.3% in anti-HCV-positive patients, 12.4% in HBsAg pos…
Caso Studio relativo ad un ipermercato ubicato in Sicilia, opportunità di risparmio energetico, studi di fattibilità
Chronic hepatitis B in Italy: New features of an old disease - Approaching the universal prevalence of hepatitis B e antigen-negative cases and the eradication of hepatitis D infection
We evaluated 1336 hepatitis B surface antigen-positive subjects consecutively observed in 79 Italian hospitals over a 6-month period. The proportion of hepatitis B e antigen-negative cases was 86.4%, that of patients coinfected with hepatitis D virus was 9.7%, and the rate of patients coinfected with hepatitis C virus was 16.8%. Multiple logistic regression analysis showed that age >49 years, alcohol abuse, and anti-hepatitis D virus and anti-hepatitis C virus positivity were independent predictors of progression to liver cirrhosis. © 2007 by the Infectious Diseases Society of America. All rights reserved.
Fish diversity associated with gas platforms: Evaluation of two underwater visual census techniques
Se estudiaron las comunidades ícticas asociadas con plataformas extractivas mediante dos técnicas de censos visuales submarinos: transectos y conteos de puntos móviles. Los datos se tomaron a cuatro profundidades en tres diferentes plataformas situadas en el Mar Jónico (Crotone, Italia). Se registraron un total de 25 especies de peces pertenecientes a 12 familias. Se observaron diferencias significativas entre ambos métodos de muestreo y las profundidades en cuanto a la estructura de la comunidad íctica, la riqueza de especies y la abundancia de peces. El promedio de peces registrado con el método de transectos siempre fue mayor que el registrado mediante puntos móviles, mientras que lo con…