Measurement of charged jet production cross sections and nuclear modification in p–Pb collisions at sNN=5.02 TeV

Charged jet production cross sections in p–Pb collisions at √sNN = 5.02 TeV measured with the ALICE detector at the LHC are presented. Using the anti-kT algorithm, jets have been reconstructed in the central rapidity region from charged particles with resolution parameters R = 0.2 and R = 0.4. The reconstructed jets have been corrected for detector effects and the underlying event background. To calculate the nuclear modification factor, RpPb, of charged jets in p–Pb collisions, a pp reference was constructed by scaling previously measured charged jet spectra at √s = 7 TeV. In the transverse momentum range 20 ≤ pT, ch jet ≤ 120 GeV/c, RpPb is found to be consistent with unity, indicating th…

Carotid plaque detection improves the predictve value of CHA2DS2-VASc score in patients with non-valvular atrial fibrilation: The ARAPACIS Study

Abstract Background and aims Vascular disease (VD), as assessed by history of myocardial infarction or peripheral artery disease or aortic plaque, increases stroke risk in atrial fibrillation (AF), and is a component of risk assessment using the CHA 2 DS 2 -VASc score. We investigated if systemic atherosclerosis as detected by ultrasound carotid plaque (CP) could improve the predictive value of the CHA 2 DS 2 -VASc score. Methods We analysed data from the ARAPACIS study, an observational study including 2027 Italian patients with non-valvular AF, in whom CP was detected using Doppler Ultrasonography. Results VD was reported in 351 (17.3%) patients while CP was detected in 16.6% patients. Ad…

Production of Muons from Heavy Flavor Decays at Forward Rapidity inppand Pb-Pb Collisions atsNN=2.76  TeV

The ALICE Collaboration has measured the inclusive production of muons from heavy-flavor decays at forward rapidity, 2.5 < y < 4, in pp and Pb-Pb collisions at root s(NN) = 2.76 TeV. The p(t)-differential inclusive cross section of muons from heavy-flavor decays in pp collisions is compared to perturbative QCD calculations. The nuclear modification factor is studied as a function of p(t) and collision centrality. A weak suppression is measured in peripheral collisions. In the most central collisions, a suppression of a factor of about 3-4 is observed in 6 < p(t) < 10 GeV/c. The suppression shows no significant p(t) dependence.

J/ψElliptic Flow in Pb-Pb Collisions atsNN=2.76  TeV

We report on the first measurement of inclusive J/psi elliptic flow v(2) in heavy-ion collisions at the LHC. The measurement is performed with the ALICE detector in Pb-Pb collisions at root s(NN) = 2.76 TeV in the rapidity range 2.5 < y < 4.0. The dependence of the J/psi v(2) on the collision centrality and on the J/psi transverse momentum is studied in the range 0 <= p(T) < 10 GeV/c. For semicentral Pb-Pb collisions at root s(NN) = 2.76 TeV, an indication of nonzero v(2) is observed with a largest measured value of v(2) = 0.116 +/-0.046(stat) +/- 0.029(syst) for J/psi in the transverse momentum range 2 <= p(T) < 4 GeV/c. The elliptic flow measurement complements the previously reported ALI…

Cellular and molecular bases of biomineralization in sea urchin embryos

Sea urchin embryos construct their skeleton following a precise gene-regulated time- and space-dependent programme, in concert with factors promoting cell adhesion and differentiation. The biomineral is deposited in a privileged extracellular space produced by the fused filopodia processes of the primary mesenchyme cells, the only cells producing a set of necessary matrix proteins. More than ten years ago we showed for the first time that signals from ectoderm cells promoted the expression of one of the major skeleton matrix genes by the primary mesenchyme cells. Since then, many of the crucial steps of this complex activation cascade, from ectoderm cells to embryonic spicules, have been el…

Elliptic flow of muons from heavy-flavour hadron decays at forward rapidity in Pb–Pb collisions at sNN=2.76 TeV

The elliptic flow, $v_{2}$, of muons from heavy-flavour hadron decays at forward rapidity ($2.5 < y < 4$) is measured in Pb--Pb collisions at $\sqrt{s_{\rm NN}}$~=~2.76 TeV with the ALICE detector at the LHC. The scalar product, two- and four-particle $Q$ cumulants and Lee-Yang zeros methods are used. The dependence of the $v_2$ of muons from heavy-flavour hadron decays on the collision centrality, in the range 0--40\%, and on transverse momentum, $p_{\rm T}$, is studied in the interval $3 < p_{\rm T} < 10$~GeV/$c$. A positive $v_2$ is observed with the scalar product and two-particle $Q$ cumulants in semi-central collisions (10--20\% and 20--40\% centrality classes) for the $p_{\rm T}$ int…

Pseudorapidity Density of Charged Particles inp+PbCollisions atsNN=5.02  TeV

The charged-particle pseudorapidity density measured over four units of pseudorapidity in nonsingle-diffractive p + Pb collisions at a center-of-mass energy per nucleon pair root s(NN) = 5.02 TeV is presented. The average value at midrapidity is measured to be 16.81 +/- 0.71 (syst), which corresponds to 2.14 +/- 0.17 (syst) per participating nucleon, calculated with the Glauber model. This is 16% lower than in nonsingle-diffractive pp collisions interpolated to the same collision energy and 84% higher than in d + Au collisions at root s(NN) = 0.2 TeV. The measured pseudorapidity density in p + Pb collisions is compared to model predictions and provides new constraints on the description of …

Centrality, rapidity and transverse momentum dependence of J/ψ suppression in Pb–Pb collisions at sNN=2.76 TeV

The inclusive J/.nuclear modification factor (R-AA) in Pb-Pb collisions at root(NN)-N-S = 2.76TeVhas been measured by ALICE as a function of centrality in the e+ e-decay channel at mid-rapidity (| y| < 0.8) and as a function of centrality, transverse momentum and rapidity in the + -decay channel at forward-rapidity (2.5 < y < 4). The J/.yields measured in Pb-Pb are suppressed compared to those in ppcollisions scaled by the number of binary collisions. The RAAintegrated over a centrality range corresponding to 90% of the inelastic Pb-Pb cross section is 0.72 - 0.06(stat.) - 0.10(syst.) at mid-rapidity and 0.58 - 0.01(stat.) - 0.09(syst.) at forward-rapidity. At low transverse momentum, signi…

KS0andΛProduction in Pb-Pb Collisions atsNN=2.76  TeV

The ALICE measurement of K^0_S and {\Lambda} production at mid-rapidity in Pb-Pb collisions at sqrt(sNN) = 2.76 TeV is presented. The transverse momentum (pT) spectra are shown for several collision centrality intervals and in the pT range from 0.4 GeV/c (0.6 GeV/c for {\Lambda}) to 12 GeV/c. The pT dependence of the {\Lambda}/K^0_S ratios exhibits maxima in the vicinity of 3 GeV/c, and the positions of the maxima shift towards higher pT with increasing collision centrality. The magnitude of these maxima increases by almost a factor of three between most peripheral and most central Pb-Pb collisions. This baryon excess at intermediate pT is not observed in pp interactions at sqrt(s) = 0.9 Te…

Flow dominance and factorization of transverse momentum correlations in Pb-Pb collisions at the LHC

Physical review letters 118(16), 162302 (2017). doi:10.1103/PhysRevLett.118.162302

Pseudorapidity dependence of the anisotropic flow of charged particles in Pb–Pb collisions at sNN=2.76 TeV

We present measurements of the elliptic ($\mathrm{v}_2$), triangular ($\mathrm{v}_3$) and quadrangular ($\mathrm{v}_4$) anisotropic azimuthal flow over a wide range of pseudorapidities ($-3.5< \eta < 5$). The measurements are performed with Pb-Pb collisions at $\sqrt{s_{\text{NN}}} = 2.76$ TeV using the ALICE detector at the Large Hadron Collider (LHC). The flow harmonics are obtained using two- and four-particle correlations from nine different centrality intervals covering central to peripheral collisions. We find that the shape of $\mathrm{v}_n(\eta)$ is largely independent of centrality for the flow harmonics $n=2-4$, however the higher harmonics fall off more steeply with increasing $|…

Inclusive quarkonium production at forward rapidity in pp collisions at \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathbf {\sqrt{s}=8}~$$\end{document}s=8TeV

We report on the inclusive production cross sections of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathrm{J}/\psi }$$\end{document}J/ψ, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\psi (\mathrm{2S})}$$\end{document}ψ(2S), \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepac…

First measurement of the |t|-dependence of coherent J/ψ photonuclear production

The first measurement of the dependence on $|t|$, the square of the momentum transferred between the incoming and outgoing target nucleus, of coherent J/ψ photoproduction is presented. The data were measured with the ALICE detector in ultra-peripheral Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the J/$\psi$ produced in the central rapidity region $|y| < 0.8$, which corresponds to the small Bjorken-$x$ range $(0.3 − 1.4) \times 10 ^{−3}$. The measured $|t|$-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according t…

Charge separation relative to the reaction plane in Pb-Pb collisions atsNN=2.76  TeV

Measurements of charge-dependent azimuthal correlations with the ALICE detector at the LHC are reported for Pb-Pb collisions at root s(NN) = 2.76 TeV. Two- and three-particle charge-dependent azimuthal correlations in the pseudorapidity range vertical bar eta vertical bar < 0.8 are presented as a function of the collision centrality, particle separation in pseudorapidity, and transverse momentum. A clear signal compatible with a charge-dependent separation relative to the reaction plane is observed, which shows little or no collision energy dependence when compared to measurements at RHIC energies. This provides a new insight for understanding the nature of the charge-dependent azimuthal co…

Long-range angular correlations of π, K and p in p–Pb collisions at sNN=5.02 TeV

Angular correlations between unidentified charged trigger particles and various species of charged associated particles (unidentified particles, pions, kaons, protons and antiprotons) are measured by the ALICE detector in p-Pb collisions at a nucleon-nucleon centre-of-mass energy of 5.02 TeV in the transverse-momentum range 0.3 < p(T) < 4 GeV/c. The correlations expressed as associated yield per trigger particle are obtained in the pseudorapidity range vertical bar n(lab)vertical bar < 0.8. Fourier coefficients are extracted from the long-range correlations projected onto the azimuthal angle difference and studied as a function of p(T) and in intervals of event multiplicity. In high-multipl…

ϕ-Meson production at forward rapidity in p–Pb collisions at sNN=5.02 TeV and in pp collisions at s=2.76 TeV

The first study of $\phi$-meson production in p–Pb collisions at forward and backward rapidity, at a nucleon– nucleon centre-of-mass energy $\sqrt{S_{NN}}$= 5.02 TeV, has been performed with the ALICE apparatus at the LHC. The $\phi$-mesons have been identified in the dimuon decay channel in the transverse momentum ($p_T$) range 1 < $p_T$ < 7 GeV/c, both in the p-going (2.03 < y < 3.53) and the Pb-going (−4.46 < y < −2.96) directions — where $y$ stands for the rapidity in the nucleon–nucleon centre-of-mass — the integrated luminosity amounting to 5.01 ± 0.19 nb$^{−1}$ and 5.81 ± 0.20 nb$^{−1}$ , respectively, for the two data samples. Differential cross sections as a function of transverse …

Anisotropic Flow of Charged Particles in Pb-Pb Collisions atsNN=5.02  TeV

We report the first results of elliptic (v2), triangular (v3), and quadrangular (v4) flow of charged particles in Pb-Pb collisions at a center-of-mass energy per nucleon pair of √sNN=5.02  TeV with the ALICE detector at the CERN Large Hadron Collider. The measurements are performed in the central pseudorapidity region |η|<0.8 and for the transverse momentum range 0.2<pT<5  GeV/c. The anisotropic flow is measured using two-particle correlations with a pseudorapidity gap greater than one unit and with the multiparticle cumulant method. Compared to results from Pb-Pb collisions at √sNN=2.76  TeV, the anisotropic flow coefficients v2, v3, and v4 are found to increase by (3.0±0.6)%, (4.3±1.4)%, …

Measuring KS0K± interactions using Pb–Pb collisions at sNN=2.76 TeV

We present the first measurements of femtoscopic correlations between the KS0 and K± particles in pp collisions at s=7 TeV measured by the ALICE experiment. The observed femtoscopic correlations are consistent with final-state interactions proceeding solely via the a0(980) resonance. The extracted kaon source radius and correlation strength parameters for KS0K− are found to be equal within the experimental uncertainties to those for KS0K+ . Results of the present study are compared with those from identical-kaon femtoscopic studies also performed with pp collisions at s=7 TeV by ALICE and with a KS0K± measurement in Pb–Pb collisions at sNN=2.76 TeV. Combined with the Pb–Pb results, our pp a…

Search for weakly decaying Λn‾ and ΛΛ exotic bound states in central Pb–Pb collisions at sNN=2.76 TeV

We present results of a search for two hypothetical strange dibaryon states, i.e. the H-dibaryon and the possible (Lambda n) over bar bound state. The search is performed with the ALICE detector in central (0-10%) Pb-Pb collisions at root S-NN = 2.76 TeV, by invariant mass analysis in the decay modes (Lambda n) over bar (d) over bar pi(+) and H-dibaryon -> Lambda p pi(-). No evidence for these bound states is observed. Upper limits are determined at 99% confidence level for a wide range of lifetimes and for the full range of branching ratios. The results are compared to thermal, coalescence and hybrid UrQMD model expectations, which describe correctly the production of other loosely bound s…

Pseudorapidity and transverse-momentum distributions of charged particles in proton–proton collisions at s=13 TeV

The pseudorapidity (η) and transverse-momentum (pT) distributions of charged particles produced in proton-proton collisions are measured at the centre-of-mass energy s√ = 13 TeV. The pseudorapidity distribution in |η|< 1.8 is reported for inelastic events and for events with at least one charged particle in | η|< 1. The pseudorapidity density of charged particles produced in the pseudorapidity region |η|< 0.5 is 5.31 ± 0.18 and 6.46 ± 0.19 for the two event classes, respectively. The transverse-momentum distribution of charged particles is measured in the range 0.15 < pT < 20 GeV/c and |η|< 0.8 for events with at least one charged particle in |η|< 1. The correlation between transverse momen…

Production of charged pions, kaons and protons at large transverse momenta in pp and Pb–Pb collisions at sNN=2.76 TeV

Transverse momentum spectra of pi(+/-), K-+/- and p((p) over bar) up to p(T) = 20 GeV/c at mid-rapidity in pp, peripheral (60-80%) and central (0-5%) Pb-Pb collisions at v root s(NN) = 2.76 TeV have been measured using the ALICE detector at the Large Hadron Collider. The proton-to-pion and the kaon-to-pionratios both show a distinct peak at p(T) approximate to 3 GeV/c in central Pb-Pb collisions. Below the peak, p(T) 10 GeV/c particle ratios in pp and Pb-Pb collisions are in agreement and the nuclear modification factors for pi(+/-), K-+/- and p((p) over bar) indicate that, within the systematic and statistical uncertainties, the suppression is the same. This suggests that the chemical comp…

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one

AB0467 EFFECTIVENESS OF GOLIMUMAB AFTER TNF-INHIBITOR FAILURE IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS, PSORIATIC ARTHRITIS, OR AXIAL SPONDYLOARTHRITIS: RESULTS AT 3 MONTHS FROM THE GO-BEYOND ITALY STUDY

Background:Golimumab showed trial efficacy in subjects with active rheumatoid arthritis (RA) previously treated with TNF-inhibitors (TNFi); no trial data are available for psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA).Objectives:To assess the effectiveness of golimumab after TNFi failure in patients with RA, PsA, or axSpA in a real-world setting.Methods:GO-BEYOND-Italy is an ongoing, multicenter, prospective, observational study of RA, PsA, or axSpA patients starting golimumab after TNFi failure. Patients were enrolled between July 2017 and December 2019, and followed for 1 year, with evaluations at 3, 6, and 12 months. This interim analysis estimates the effectiveness after…

Charged jet cross sections and properties in proton-proton collisions at $\sqrt{s}=7$ TeV

The differential charged jet cross sections, jet fragmentation distributions, and jet shapes are measured in minimum bias proton-proton collisions at centre-of-mass energy $\sqrt{s}=7$ TeV using the ALICE detector at the LHC. Jets are reconstructed from charged particle momenta in the mid-rapidity region using the sequential recombination $k_{\rm T}$ and anti-$k_{\rm T}$ as well as the SISCone jet finding algorithms with several resolution parameters in the range $R=0.2$ to $0.6$. Differential jet production cross sections measured with the three jet finders are in agreement in the transverse momentum ($p_{\rm T}$) interval $20<p_{\rm T}^{\rm jet,ch}<100$ GeV/$c$. They are also consistent w…

Charged kaon femtoscopic correlations inppcollisions ats=7  TeV

Correlations of two charged identical kaons (KchKch) are measured in pp collisions at root s = 7 TeV by the ALICE experiment at the Large Hadron Collider (LHC). One-dimensional (KKch)-K-ch correlation functions are constructed in three multiplicity and four transverse momentum ranges. The (KKch)-K-ch femtoscopic source parameters R and lambda are extracted. The (KKch)-K-ch correlations show a slight increase of femtoscopic radii with increasing multiplicity and a slight decrease of radii with increasing transverse momentum. These trends are similar to the ones observed for pi pi and K-s(0) K-s(0) correlations in pp and heavy-ion collisions. However at high multiplicities, there is an indica…

Measurement of pion, kaon and proton production in proton–proton collisions at \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\sqrt{s} = 7$$\end{document}s=7 TeV

The measurement of primary \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\pi ^{\pm }$$\end{document}π±, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$K^{\pm }$$\end{document}K±, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrs…

Forward-central two-particle correlations in p–Pb collisions at sNN=5.02 TeV

Two-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 < |η| < 4.0) and associated particles in the cen

Ds+ meson production at central rapidity in proton–proton collisions at s=7 TeV

The pt-differential inclusive production cross section of the prompt charm-strange meson D_s in the rapidity range |y| phi pi, with phi -> KK, and its charge conjugate, about 480 D_s mesons were counted, after selection cuts, in the transverse momentum range 2

Linear and non-linear flow mode in Pb–Pb collisions at sNN=2.76 TeV

The second and the third order anisotropic flow, V2 and V3, are mostly determined by the corresponding initial spatial anisotropy coefficients, e2 and e3, in the initial density distribution. In addition to their dependence on the same order initial anisotropy coefficient, higher order anisotropic flow, Vn (n > 3), can also have a significant contribution from lower order initial anisotropy coefficients, which leads to mode-coupling effects. In this Letter we investigate the linear and non-linear modes in higher order anisotropic flow Vn for n = 4, 5, 6 with the ALICE detector at the Large Hadron Collider. The measurements are done for particles in the pseudorapidity range |η| < 0.8 and the…

EPIDEMIOLOGICAL SURVEILLANCE OF VISCERAL LEISHMANIASIS IN SICILY, ITALY

Abstract Visceral leishmaniasis (VL) is endemic in Sicily. Although it is a notifiable disease, there is evidence that the actual number of cases is higher than that reported. In 1987, a regional reference center for active surveillance of VL was established and it recorded a total of 284 cases through 1995, a mean of 31.5 cases/year and about four-fold more than previously reported. Of the 284 cases, 150 (53%) were children (≤ 14 years of age), and of the 134 adults, 39 (29%) were coinfected with human immunodeficiency virus (HIV). The commonest viscerotropic zymodeme of Leishmania infantum, MON 1, was identified in 40 (93%) of 43 HIV-negative and eight (57%) of 14 HIV-positive patients. A…

Production of K\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$^{*}$$\end{document}∗(892)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$^{0}$$\end{document}0 and \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\phi $$\end{document}ϕ(1020) in p–Pb collisions at \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\sqrt{s_{{\text {NN}}}}$$\end{document}sNN = 5.02 TeV

The production of K\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$^{*}$$\end{document}∗(892)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$^{0}$$\end{document}0 and \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage…

Azimuthally Differential Pion Femtoscopy in Pb-Pb Collisions at sNN=2.76  TeV

We present the first azimuthally differential measurements of the pion source size relative to the second harmonic event plane in Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon pair of √sNN = 2.76 TeV. The measurements have been performed in the centrality range 0%-50% and for pion pair transverse momenta 0.2 < kT < 0.7 GeV/c. We find that the Rside and Rout radii, which characterize the pion source size in the directions perpendicular and parallel to the pion transverse momentum, oscillate out of phase, similar to what was observed at the Relativistic Heavy Ion Collider. The final-state source eccentricity, estimated via Rside oscillations, is found to be significantly sma…

Direct photon production in Pb–Pb collisions atsNN=2.76 TeV

Direct photon production at mid-rapidity in Pb–Pb collisions at √sNN = 2.76 TeV was studied in the transverse momentum range 0.9<pT<14 GeV/c. Photons were detected with the highly segmented electromagnetic calorimeter PHOS and via conversions in the ALICE detector material with the e+e− pair reconstructed in the central tracking system. The results of the two methods were combined and direct photon spectra were measured for the 0–20%, 20–40%, and 40–80% centrality classes. For all three classes, agreement was found with perturbative QCD calculations for pT≳5 GeV/c. Direct photon spectra down to pT≈1 GeV/c could be extracted for the 20–40% and 0–20% centrality classes. The significance of th…

Production of muons from heavy-flavour hadron decays in p–Pb collisions at sNN=5.02 TeV

Abstract The production of muons from heavy-flavour hadron decays in p–Pb collisions at s NN = 5.02 TeV was studied for 2 p T 16 GeV/c with the ALICE detector at the CERN LHC. The measurement was performed at forward (p-going direction) and backward (Pb-going direction) rapidity, in the ranges of rapidity in the centre-of-mass system (cms) 2.03 y cms 3.53 and − 4.46 y cms − 2.96 , respectively. The production cross sections and nuclear modification factors are presented as a function of transverse momentum ( p T ). At forward rapidity, the nuclear modification factor is compatible with unity while at backward rapidity, in the interval 2.5 p T 3.5 GeV/c, it is above unity by more than 2σ. Th…

Precision measurement of the mass difference between light nuclei and anti-nuclei

The measurement of the mass differences for systems bound by the strong force has reached a very high precision with protons and anti-protons. The extension of such measurement from (anti-)baryons to (anti-)nuclei allows one to probe any difference in the interactions between nucleons and anti-nucleons encoded in the (anti-)nuclei masses. This force is a remnant of the underlying strong interaction among quarks and gluons and can be described by effective theories, but cannot yet be directly derived from quantum chromodynamics. Here we report a measurement of the difference between the ratios of the mass and charge of deuterons and anti-deuterons, and $^{3}{\rm He}$ and $^3\overline{\rm He}…

Centrality dependence of the pseudorapidity density distribution for charged particles in Pb–Pb collisions at sNN=2.76 TeV

We present the charged-particle pseudorapidity density in Pb-Pb collisions at $\sqrt{s_{\mathrm{NN}}}=5.02\,\mathrm{Te\kern-.25exV}$ in centrality classes measured by ALICE. The measurement covers a wide pseudorapidity range from $-3.5$ to $5$, which is sufficient for reliable estimates of the total number of charged particles produced in the collisions. For the most central (0-5%) collisions we find $21\,400\pm 1\,300$ while for the most peripheral (80-90%) we find $230\pm 38$. This corresponds to an increase of $(27\pm4)\%$ over the results at $\sqrt{s_{\mathrm{NN}}}=2.76\,\mathrm{Te\kern-.25exV}$ previously reported by ALICE. The energy dependence of the total number of charged particles…

In vivo evaluation of periodontal microcirculatory changes associated with endodontic treatment.

The purpose of this study was to investigate in vivo the gingival microcirculatory changes associated with endodontic treatment using the continuous wave of condensation technique. MATERIALS AND METHODS: Twenty necrotic one canal roots of 20 cooperative patients of both sexes, aged between 20 and 43 years, were selected. All patients were examined by capillaroscopy before, immediately after endodontic treatment, and after 7 days. The last examination was carried out by the same operator, and repeated twice for each examined area: masticatory, buccal and labial mucosa corresponding to the endodontically treated root. All canals were prepared using a simultaneous technique with Ni-Ti files (M…

Study of cosmic ray events with high muon multiplicity using the ALICE detector at the CERN Large Hadron Collider

ALICE is one of four large experiments at the CERN Large Hadron Collider near Geneva, specially designed to study particle production in ultra-relativistic heavy-ion collisions. Located 52 meters underground with 28 meters of overburden rock, it has also been used to detect muons produced by cosmic ray interactions in the upper atmosphere. In this paper, we present the multiplicity distribution of these atmospheric muons and its comparison with Monte Carlo simulations. This analysis exploits the large size and excellent tracking capability of the ALICE Time Projection Chamber. A special emphasis is given to the study of high multiplicity events containing more than 100 reconstructed muons a…

Beauty production in pp collisions at s=2.76 TeV measured via semi-electronic decays

The ALICE Collaboration at the LHC reports measurement of the inclusive production cross section of electrons from semi-leptonic decays of beauty hadrons with rapidity |y|<0.8 and transverse momentum 1<pT<10 GeV/c, in pp collisions at s=2.76 TeV. Electrons not originating from semi-electronic decay of beauty hadrons are suppressed using the impact parameter of the corresponding tracks. The production cross section of beauty decay electrons is compared to the result obtained with an alternative method which uses the distribution of the azimuthal angle between heavy-flavour decay electrons and charged hadrons. Perturbative QCD predictions agree with the measured cross section within the exper…

Rediscovery of the enigmatic solifuges (Arachnida: Solifugae) at Lampedusa Island (Italy)

Solifuges were recorded in Italy for the first time in 1956, on the island of Lampedusa (Strait of Sicily), and classified as Biton ehrenbergi Karsch, 1880 and Biton velox Simon, 1885. More than 60 years later, we carried out the first targeted investigation of these little-known animals. A survey conducted during both spring and autumn 2017 confirmed the presence of solifuges on Lampedusa Island. We identified all specimens as B. velox and not B. ehrenbergi. We concluded that B. ehrenbergi is absent from the island, on the basis of both newly collected data and a re-evaluation of the past records. Morphology and taxonomic position of the examined specimens are discussed in light of the unr…

Multi-strange baryon production in p Pb collisions at sNN=5.02 TeV

The multi-strange baryon yields in Pb--Pb collisions have been shown to exhibit an enhancement relative to pp reactions. In this work, $\Xi$ and $\Omega$ production rates have been measured with the ALICE experiment as a function of transverse momentum, ${p_{\rm T}}$, in p-Pb collisions at a centre-of-mass energy of ${\sqrt{s_{\rm NN}}}$ = 5.02 TeV. The results cover the kinematic ranges 0.6 GeV/$c<{p_{\rm T}} <$7.2 GeV/$c$ and 0.8 GeV/$c<{p_{\rm T}}<$ 5 GeV/$c$, for $\Xi$ and $\Omega$ respectively, in the common rapidity interval -0.5 $<{y_{\rm CMS}}<$ 0. Multi-strange baryons have been identified by reconstructing their weak decays into charged particles. The ${p_{\rm T}}$ spectra are ana…

Five-year retrospective italian multicenter study of visceral leishmaniasis treatment.

ABSTRACT The treatment of visceral leishmaniasis (VL) is poorly standardized in Italy in spite of the existing evidence. All consecutive patients with VL admitted at 15 Italian centers as inpatients or outpatients between January 2004 and December 2008 were retrospectively considered; outcome data at 1 year after treatment were obtained for all but 1 patient. Demographic characteristics, underlying diseases, diagnostic procedures, treatment regimens and outcomes, as well as side effects were recorded. A confirmed diagnosis of VL was reported for 166 patients: 120 (72.3%) immunocompetent, 21 (12.6%) patients with immune deficiencies other than HIV infection, and 25 (15.1%) coinfected with HI…

Dignosis and treatment of dens invaginatus with open apex in adult patient, by using cone-beam computed tomography and operative microscope

Transverse Momentum Distribution and Nuclear Modification Factor of Charged Particles inp+PbCollisions atsNN=5.02  TeV

The transverse momentum (pT) distribution of primary charged particles is measured in minimum bias (non-single-diffractive) p + Pb collisions at root(NN)-N-s = 5.02 TeV with the ALICE detector at the LHC. The pT spectra measured near central rapidity in the range 0.5< p(T) < 20 GeV/c exhibit a weak pseudorapidity dependence. The nuclear modification factor R-pPb is consistent with unity for p(T) above 2 GeV/c. This measurement indicates that the strong suppression of hadron production at high p(T) observed in Pb + Pb collisions at the LHC is not due to an initial-state effect. The measurement is compared to theoretical calculations. DOI: 10.1103/PhysRevLett.110.082302

Centrality Dependence of the Charged-Particle Multiplicity Density at Midrapidity in Pb-Pb Collisions atsNN=5.02  TeV

The pseudorapidity density of charged particles, dNch/dη, at midrapidity in Pb-Pb collisions has been measured at a center-of-mass energy per nucleon pair of √sNN=5.02 TeV. For the 5% most central collisions, we measure a value of 1943 ± 54. The rise in dNch/dη as a function of √sNN p is steeper than that observed in proton-proton collisions and follows the trend established by measurements at lower energy. The increase of dNch/dη as a function of the average number of participant nucleons, ⟨Npart⟩, calculated in a Glauber model, is compared with the previous measurement at √sNN=2.76 TeV. A constant factor of about 1.2 describes the increase in dNch/dη from √sNN=2.76 to 5.02 TeV for all cen…

Measurement of quarkonium production at forward rapidity in \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathbf {pp}$$\end{document}pp collisions at \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathbf {\sqrt{s}=7}~$$\end{document}s=7TeV

The inclusive production cross sections at forward rapidity of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathrm{J}/\psi }$$\end{document}J/ψ, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\psi (\mathrm{2S})}$$\end{document}ψ(2S), \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} …

Centrality dependence of charged jet production in p–Pb collisions at \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\sqrt{s_\mathrm{NN}}$$\end{document}sNN = 5.02 TeV

Measurements of charged jet production as a function of centrality are presented for  p–Pb  collisions recorded at \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\sqrt{s_\mathrm {NN}}= 5.02$$\end{document}sNN=5.02 TeV with the ALICE detector. Centrality classes are determined via the energy deposit in neutron calorimeters at zero degree, close to the beam direction, to minimise dynamical biases of the selection. The corresponding number of participants or binary nucleon–nucleon collisions is determined based on…

ON THE MEASUREMENT OF MASS TRANSFER COEFFICIENT KLA IN GAS-LIQUID CONTACTORS VIA OXYGEN CONCENTRATION DYNAMICS

Azimuthal anisotropy of charged jet production in sNN=2.76 TeV Pb–Pb collisions

We present measurements of the azimuthal dependence of charged jet production in central and semicentral √sNN = 2.76 TeV Pb–Pb collisions with respect to the second harmonic event plane, quantified as vch jet 2 . Jet finding is performed employing the anti-kT algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero vch jet 2 is observed in semi-central …

Determination of the event collision time with the ALICE detector at the LHC

The European physical journal / Plus 132(2), 99 (2017). doi:10.1140/epjp/i2017-11279-1

Performance of the ALICE VZERO system

ALICE is an LHC experiment devoted to the study of strongly interacting matter in proton-proton, proton--nucleus and nucleus-nucleus collisions at ultra-relativistic energies. The ALICE VZERO system, made of two scintillator arrays at asymmetric positions, one on each side of the interaction point, plays a central role in ALICE. In addition to its core function as a trigger, the VZERO system is used to monitor LHC beam conditions, to reject beam-induced backgrounds and to measure basic physics quantities such as luminosity, particle multiplicity, centrality and event plane direction in nucleus-nucleus collisions. After describing the VZERO system, this publication presents its performance o…

Coherent ψ(2S) photo-production in ultra-peripheral Pb Pb collisions at sNN=2.76 TeV

We have performed the first measurement of the coherent ψ(2S) photo-production cross section in ultraperipheral Pb–Pb collisions at the LHC. This charmonium excited state is reconstructed via the ψ(2S) → l +l − and ψ(2S) → J/ψπ+π− decays, where the J/ψ decays into two leptons. The analysis is based on an event sample corresponding to an integrated luminosity of about 22 μb−1. The cross section for coherent ψ(2S) production in the rapidity interval −0.9 < y < 0.9 is dσcoh ψ(2S)/dy = 0.83±0.19 stat+syst mb. The ψ(2S) to J/ψ coherent cross section ratio is 0.34+0.08 −0.07(stat + syst). The obtained results are compared to predictions from theoretical models.

Suppression of ϒ(1S) at forward rapidity in Pb–Pb collisions at sNN=2.76 TeV

We report on the measurement of the inclusive Υ (1S) production in Pb–Pb collisions at √sNN = 2.76 TeV carried out at forward rapidity (2.5 < y < 4) and down to zero transverse momentum using its μ+μ− decay channel with the ALICE detector at the Large Hadron Collider. A strong suppression of the inclusive Υ (1S) yield is observed with respect to pp collisions scaled by the number of independent nucleon– nucleon collisions. The nuclear modification factor, for events in the 0–90% centrality range, amounts to 0.30 ± 0.05(stat) ± 0.04(syst). The observed Υ (1S) suppression tends to increase with the centrality of the collision and seems more pronounced than in corresponding mid-rapidity measur…

Measurement of electrons from heavy-flavour hadron decays in p–Pb collisions at sNN=5.02TeV

The production of electrons from heavy-flavour hadron decays was measured as a function of transverse momentum (pT) in minimum-bias p–Pb collisions at √sNN = 5.02 TeV using the ALICE detector at the LHC. The measurement covers the pT interval 0.5 < pT < 12 GeV/c and the rapidity range −1.065 < ycms < 0.135 in the centre-of-mass reference frame. The contribution of electrons from background sources was subtracted using an invariant mass approach. The nuclear modification factor RpPb was calculated by comparing the pT-differential invariant cross section in p–Pb collisions to a pp reference at the same centre-of-mass energy, which was obtained by interpolating measurements at √s = 2.76 TeV an…

Centrality determination of Pb-Pb collisions atsNN=2.76TeV with ALICE

This publication describes the methods used to measure the centrality of inelastic Pb-Pb collisions at a center-of-mass energy of 2.76 TeV per colliding nucleon pair with ALICE. The centrality is a key parameter in the study of the properties of QCD matter at extreme temperature and energy density, because it is directly related to the initial overlap region of the colliding nuclei. Geometrical properties of the collision, such as the number of participating nucleons and the number of binary nucleon-nucleon collisions, are deduced from a Glauber model with a sharp impact parameter selection and shown to be consistent with those extracted from the data. The centrality determination provides …

Measurement of jet suppression in central Pb–Pb collisions at sNN=2.76 TeV

The transverse momentum(p(T)) spectrum and nuclear modification factor (R-AA) of reconstructed jets in 0-10% and 10-30% central Pb-Pb collisions at root s(NN) = 2.76 TeV were measured. Jets were reconstructed using the anti-k(T) jet algorithm with a resolution parameter of R = 0.2 from charged and neutral particles, utilizing the ALICE tracking detectors and Electromagnetic Calorimeter (EMCal). The jet p(T) spectra are reported in the pseudorapidity interval of \eta(jet)\ 5 GeV/c to suppress jets constructed from the combinatorial background in Pb-Pb collisions. The leading charged particle requirement applied to jet spectra both in pp and Pb-Pb collisions had a negligible effect on the R-A…

The 2014 lifetime immunization schedule approved by the Italian scientific societies. Italian Society of Hygiene, Preventive Medicine, and Public Health. Italian Society of Pediatrics. Italian Federation of Pediatric Physicians. Italian Federation of General Medical Physicians. Arezzo Service of Legal Medicine,Il calendario vaccinale per la vita 2014 predisposto dalle società scientifiche italiane

Multiplicity dependence of charged pion, kaon, and (anti)proton production at large transverse momentum in p–Pb collisions at sNN=5.02 TeV

The production of charged pions, kaons and (anti)protons has been measured at mid-rapidity ($-0.5 10$ GeV/$c$), the particle ratios are consistent with those reported for pp and Pb-Pb collisions at the LHC energies. At intermediate $p_{\rm T}$ the (anti)proton $R_{\rm pPb}$ shows a Cronin-like enhancement, while pions and kaons show little or no nuclear modification. At high $p_{\rm T}$ the charged pion, kaon and (anti)proton $R_{\rm pPb}$ are consistent with unity within statistical and systematic uncertainties.

Centrality evolution of the charged-particle pseudorapidity density over a broad pseudorapidity range in Pb–Pb collisions at sNN=2.76 TeV

State Committee of Science, World Federation of Scientists (WFS) and Swiss Fonds Kidagan, Armenia; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Financiadora de Estudos e Projetos (FINEP), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP); National Natural Science Foundation of China (NSFC), the Chinese Ministry of Education (CMOE) and the Ministry of Science and Technology of China (MSTC); Ministry of Education and Youth of the Czech Republic; Danish Natural Science Research Council, the Carlsberg Foundation and the Danish National Research Foundation; The European Research Council under the European Community's Seventh Framework Programme; Helsinki Inst…

Measurement of an Excess in the Yield ofJ/ψat Very LowpTin Pb–Pb Collisions atsNN=2.76  TeV

We report on the first measurement of an excess in the yield of J/ψ at very low transverse momentum (pT< 0.3 GeV/c) in peripheral hadronic Pb-Pb collisions at √sNN = 2.76 TeV, performed by ALICE at the CERN LHC. Remarkably, the measured nuclear modification factor of J/ψ in the rapidity range 2.5< y< 4 reaches about 7 (2) in the pT range 0- 0.3 GeV/c in the 70-90% (50-70%) centrality class. The J/ψ production cross section associated with the observed excess is obtained under the hypothesis that coherent photoproduction of J/ψ is the underlying physics mechanism. If confirmed, the observation of J/ψ coherent photoproduction in Pb-Pb collisions at impact parameters smaller than twice the nuc…

Centrality dependence ofπ,K, andpproduction in Pb-Pb collisions atsNN=2.76TeV

In this paper measurements are presented of pi(+/-), K-+/-, p, and (p) over bar production at midrapidity (vertical bar y vertical bar < 0.5), in Pb-Pb collisions at root s(NN) = 2.76 TeV as a function of centrality. The measurement covers the transverse-momentum (p(T)) range from 100, 200, and 300 MeV/c up to 3, 3, and 4.6 GeV/c for pi, K, and p, respectively. The measured p(T) distributions and yields are compared to expectations based on hydrodynamic, thermal and recombination models. The spectral shapes of central collisions show a stronger radial flow than measured at lower energies, which can be described in hydrodynamic models. In peripheral collisions, the p(T) distributions are not…

Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions atsNN=2.76TeV

We report on results obtained with the event-shape engineering technique applied to Pb-Pb collisions at √sNN=2.76 TeV. By selecting events in the same centrality interval, but with very different average flow, different initial-state conditions can be studied. We find the effect of the event-shape selection on the elliptic flow coefficient v2 to be almost independent of transverse momentum pT, which is as expected if this effect is attributable to fluctuations in the initial geometry of the system. Charged-hadron, -pion, -kaon, and -proton transverse momentum distributions are found to be harder in events with higher-than-average elliptic flow, indicating an interplay between radial and ell…

Production of inclusive ϒ(1S) and ϒ(2S) in p–Pb collisions at sNN=5.02 TeV

We report on the production of inclusive Y{hooktop}(1S) and Y{hooktop}(2S) in p-Pb collisions at √sNN=5.02 TeV at the LHC. The measurement is performed with the ALICE detector at backward (-4.46<ycms<-2.96) and forward (2.03<ycms<3.53) rapidity down to zero transverse momentum. The production cross sections of the Y{hooktop}(1S) and Y{hooktop}(2S) are presented, as well as the nuclear modification factor and the ratio of the forward to backward yields of Y{hooktop}(1S). A suppression of the inclusive Y{hooktop}(1S) yield in p-Pb collisions with respect to the yield from pp collisions scaled by the number of binary nucleon-nucleon collisions is observed at forward rapidity but not at backwar…

Energy dependence of the transverse momentum distributions of charged particles in pp collisions measured by ALICE

Differential cross sections of charged particles in inelastic pp collisions as a function of $p_{\rm T}$ have been measured at $\sqrt{s}=$ 0.9, 2.76 and 7 TeV at the LHC. The $p_{\rm T}$ spectra are compared to NLO-pQCD calculations. Though the differential cross section for an individual $\sqrt{s}$ cannot be described by NLO-pQCD, the relative increase of cross section with $\sqrt{s}$ is in agreement with NLO-pQCD. Based on these measurements and observations, procedures are discussed to construct pp reference spectra at $\sqrt{s} =$ 2.76 and 5.02 TeV up to $p_{\rm T}$ = 50 GeV/$c$ as required for the calculation of the nuclear modification factor in nucleus-nucleus and proton-nucleus coll…

Measurement of visible cross sections in proton-lead collisions at √sNN= 5.02 TeV in van der Meer scans with the ALICE detector

In 2013, the Large Hadron Collider provided proton-lead and lead-proton collisions at the center-of-mass energy per nucleon pair $\sqrt{s_{\rm{NN}}}=5.02$ TeV. Van der Meer scans were performed for both configurations of colliding beams, and the cross section was measured for two reference processes, based on particle detection by the T0 and V0 detectors, with pseudo-rapidity coverage $4.6<\eta< 4.9$, $-3.3<\eta<-3.0$ and $2.8<\eta< 5.1$, $-3.7<\eta<-1.7$, respectively. Given the asymmetric detector acceptance, the cross section was measured separately for the two configurations. The measured visible cross sections are used to calculate the integrated luminosity of the proton-lead and lead-…

K*(892)0 and ϕ(1020) meson production at high transverse momentum in pp and Pb-Pb collisions at sNN=2.76 TeV

The yields of the K*(892)(0) and phi(1020) resonances are measured in Pb-Pb collisions at root s(NN) = 2.76 TeV through their hadronic decays using the ALICE detector. The measurements are performed in multiple centrality intervals at mid-rapidity (vertical bar y vertical bar <0.5) in the transverse-momentum ranges 0.3 <p(T) <5 GeV/c for the K*(892)(0) and 0.5 <p(T) <5 GeV/c for the phi(1020). The yields of K*(892)(0) are suppressed in central Pb-Pb collisions with respect to pp and peripheral Pb-Pb collisions (perhaps due to rescattering of its decay products in the hadronic medium), while the longer-lived phi(1020) meson is not suppressed. These particles are also used as probes to study …

Correlated Event-by-Event Fluctuations of Flow Harmonics in Pb-Pb Collisions at sNN=2.76  TeV

We report the measurements of correlations between event-by-event fluctuations of amplitudes of anisotropic flow harmonics in nucleus-nucleus collisions, obtained for the first time using a new analysis method based on multiparticle cumulants in mixed harmonics. This novel method is robust against systematic biases originating from non-flow effects and by construction any dependence on symmetry planes is eliminated. We demonstrate that correlations of flow harmonics exhibit a better sensitivity to medium properties than the individual flow harmonics. The new measurements are performed in Pb-Pb collisions at the centre-of-mass energy per nucleon pair of $\sqrt{s_{_{\rm NN}}}=2.76$ TeV by the…

Particle identification in ALICE: a Bayesian approach

We present a Bayesian approach to particle identification (PID) within the ALICE experiment. The aim is to more effectively combine the particle identification capabilities of its various detectors. After a brief explanation of the adopted methodology and formalism, the performance of the Bayesian PID approach for charged pions, kaons and protons in the central barrel of ALICE is studied. PID is performed via measurements of specific energy loss ($\mathrm{d}E/\mathrm{d}x$) and time-of-flight. PID efficiencies and misidentification probabilities are extracted and compared with Monte Carlo simulations using high-purity samples of identified particles in the decay channels ${\rm K}^0_S \righta…

Genome wide survey of the Toll-like receptor family in the Mediterranean sea urchin

Toll-like receptors (TLRs) represent a conserved family of proteins widely expressed in eukaryotes. They play crucial roles in the innate immune system recognizing different pathogen-associated molecular patterns. In mammals the TLR family comprises 10-13 members, while a huge number of TLR-like genes were recovered in S.purpuratus[1-3]. The Paracentrotus lividus genome project recently generated a new highquality assembly of the genome that represents a valuable resource also for clarifying the evolutionary origin of immune system. In order to identify TLR genes in P.lividus, a genome wide survey was carried out and BLAT searches retrieved 119 TLR genes (PlivTLRs). Ab initio gene predictio…

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

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The combined distribution/assignment problem in transportation network planning: a parallel approach on hypercube architecture

The joint distribution/assignment problem plays a central role in urban transport network planning. In this problem, according to the mathematical model proposed by S. P. Evans, the trips are iteratively calculated and assigned to the network in such a way that the resulting traffic flows pattern satisfies the selfish equilibrium condition. Unfortunately the number of variables and constraints increase hardly with the greatness of the networks causing long computational time for the equilibrium solution. In this paper an nCUBE 2 parallel computing architecture is employed to solve the combined problem and to asses the potential of MIMD machines to handle large scale transportation network p…

Centrality dependence of the nuclear modification factor of charged pions, kaons, and protons in Pb-Pb collisions atsNN=2.76TeV

Transverse momentum (pT) spectra of pions, kaons, and protons up to pT=20GeV/c have been measured in Pb-Pb collisions at √sNN=2.76TeV using the ALICE detector for six different centrality classes covering 0%–80%. The proton-to-pion and the kaon-to-pion ratios both show a distinct peak at pT≈3GeV/c in central Pb-Pb collisions that decreases for more peripheral collisions. For pT>10GeV/c, the nuclear modification factor is found to be the same for all three particle species in each centrality interval within systematic uncertainties of 10%–20%. This suggests there is no direct interplay between the energy loss in the medium and the particle species composition in the hard core of the quenched…

J/ production as a function of charged-particle pseudorapidity density in p–Pb collisions at

We report measurements of the inclusive J/ψ yield and average transverse momentum as a function of charged-particle pseudorapidity density dNch/dη in p–Pb collisions at sNN=5.02TeV with ALICE at the LHC. The observables are normalised to their corresponding averages in non-single diffractive events. An increase of the normalised J/ψ yield with normalised dNch/dη, measured at mid-rapidity, is observed at mid-rapidity and backward rapidity. At forward rapidity, a saturation of the relative yield is observed for high charged-particle multiplicities. The normalised average transverse momentum at forward and backward rapidities increases with multiplicity at low multiplicities and saturates beyo…