0000000000219305

AUTHOR

Iosif Lazaridis

showing 9 related works from this author

Reconstructing the deep population history of Central and South America

2018

We report genome-wide ancient DNA from 49 individuals forming four parallel time transects in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least ∼9,000 years ago. The common ancestral population radiated rapidly from just one of the two early branches that contributed to Native Americans today. We document two previously unappreciated streams of gene flow between North and South America. One affected the Central Andes by ∼4,200 years ago, while the other explains an affinity between the oldest North American genome associated with the Clovis culture and the oldest Central and South Americans from Chile, Brazil, and Belize. However, this was not the primary sou…

0301 basic medicineGene Flow010506 paleontologyHistoryPopulationPopulationPopulation ReplacementBiology01 natural sciencesGenomeMedical and Health SciencesDNA MitochondrialGeneral Biochemistry Genetics and Molecular BiologyGene flowAncient03 medical and health sciencesTheoreticalModelsGeneticsHumansGENÉTICA DE POPULAÇÕESanthropologyIndis de l'Amèrica CentralDNA AncientTransecteducationHistory Ancient0105 earth and related environmental scienceseducation.field_of_studypopulation geneticGenomeGenome HumanHuman Genomepopulation geneticsarchaeologyCentral AmericaDNABiological SciencesSouth AmericaModels TheoreticalArchaeologyMitochondrial030104 developmental biologyAncient DNAGenetics PopulationDevelopmental BiologyHuman
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The Arrival of Steppe and Iranian Related Ancestry in the Islands of the Western Mediterranean

2019

A series of studies have documented how Steppe pastoralist-related ancestry reached central Europe by at least 2500 BCE, while Iranian farmer-related ancestry was present in Aegean Europe by at least 1900 BCE. However, the spread of these ancestries into the western Mediterranean where they have contributed to many populations living today remains poorly understood. We generated genome-wide ancient DNA from the Balearic Islands, Sicily, and Sardinia, increasing the number of individuals with reported data from these islands from 3 to 52. We obtained data from the oldest skeleton excavated from the Balearic islands (dating to ∼2400 BCE), and show that this individual had substantial Steppe p…

Mediterranean climate0303 health sciencesBalearic islandsgeographygeography.geographical_feature_categorySteppemedia_common.quotation_subjectImmigrationPastoralismgovernment.political_districtAncient historyhumanities03 medical and health sciences0302 clinical medicineAncient DNABronze AgeClassical periodgovernment030217 neurology & neurosurgery030304 developmental biologymedia_common
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Massive migration from the steppe was a source for Indo-European languages in Europe

2015

We generated genome-wide data from 69 Europeans who lived between 8,000-3,000 years ago by enriching ancient DNA libraries for a target set of almost four hundred thousand polymorphisms. Enrichment of these positions decreases the sequencing required for genome-wide ancient DNA analysis by a median of around 250-fold, allowing us to study an order of magnitude more individuals than previous studies and to obtain new insights about the past. We show that the populations of western and far eastern Europe followed opposite trajectories between 8,000-5,000 years ago. At the beginning of the Neolithic period in Europe, ~8,000-7,000 years ago, closely related groups of early farmers appeared in G…

MaleArchaeogeneticsSteppeHuman MigrationPopulation DynamicsPopulationAncient historyCorded Ware cultureIndigenousArticleRussia03 medical and health sciencesCultural EvolutionHumans0601 history and archaeologyQuantitative Biology - Populations and EvolutioneducationHistory AncientLanguage030304 developmental biology0303 health sciencesgeographyeducation.field_of_studyPolymorphism GeneticMultidisciplinarygeography.geographical_feature_category060102 archaeologyGenome HumanIndo-European languagesPopulations and Evolution (q-bio.PE)Languages of Europe06 humanities and the artsGrasslandEuropeEastern europeanAncient DNAFOS: Biological sciencesPeriod (geology)Ethnology
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The beaker phenomenon and the Genomic transformations of Northwest Europe

2018

Bell Beaker pottery spread across western and central Europe beginning around 2750 BCE before disappearing between 2200–1800 BCE. The mechanism of its expansion is a topic of long-standing debate, with support for both cultural diffusion and human migration. We present new genome-wide ancient DNA data from 170 Neolithic, Copper Age and Bronze Age Europeans, including 100 Beaker-associated individuals. In contrast to the Corded Ware Complex, which has previously been identified as arriving in central Europe following migration from the east, we observe limited genetic affinity between Iberian and central European Beaker Complex-associated individuals, and thus exclude migration as a signific…

Male0301 basic medicineSteppeADNNéolithiqueBell BeakerArqueologiaBell Beaker culturegenome wide ancient DNA0302 clinical medicineArchéologiePhenomenonddc:5500601 history and archaeologySuisseHistory Ancient0303 health scienceseducation.field_of_studygeography.geographical_feature_categoryMultidisciplinary060102 archaeology[SDE.IE]Environmental Sciences/Environmental EngineeringHuman migrationPréhistoireNeolithic periodGene PoolGenomics[SHS.GEO]Humanities and Social Sciences/Geography06 humanities and the artsbell BeakerEuropeGeographyArchaeologyCeràmicaEthnologyMégalithisme1000ArchaeogeneticsCampaniformePotteryHuman Migration[SDE.MCG]Environmental Sciences/Global ChangesPopulationAncient historyArticle03 medical and health sciencesSpatio-Temporal Analysispopular geneticsBronze AgeBeakerCultural EvolutionNeolíticgenomicsHumansDNA Ancienteducation030304 developmental biologyChromosomes Human YGenome Humanbusiness.industryNorthwest Europebell Beaker; genome wide ancient DNA; EuropeChalcolithic[SDE.ES]Environmental Sciences/Environmental and SocietyAncient DNAGenetics Population030104 developmental biologyHaplotypesPeriod (geology)GenomicPottery[SDE.BE]Environmental Sciences/Biodiversity and Ecologybusiness030217 neurology & neurosurgery
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The spread of steppe and Iranian-related ancestry in the islands of the western Mediterranean

2020

Steppe-pastoralist-related ancestry reached Central Europe by at least 2500 bc, whereas Iranian farmer-related ancestry was present in Aegean Europe by at least 1900 bc. However, the spread of these ancestries into the western Mediterranean, where they have contributed to many populations that live today, remains poorly understood. Here, we generated genome-wide ancient-DNA data from the Balearic Islands, Sicily and Sardinia, increasing the number of individuals with reported data from 5 to 66. The oldest individual from the Balearic Islands (~2400 bc) carried ancestry from steppe pastoralists that probably derived from west-to-east migration from Iberia, although two later Balearic individ…

0301 basic medicineMediterranean climateSteppePastoralismPopulation geneticsgovernment.political_districtSettore BIO/08 - AntropologiaIranancient-DNA western mediterranean islands populationaDNA Human Ancient migrations Western Mediterranean Basin Steppe pastoralists Anthropology03 medical and health sciences0302 clinical medicineBronze AgeHumansDNA AncientSicilyEcology Evolution Behavior and SystematicsIslandsBalearic islandsgeography.geographical_feature_categoryEcologyAfrica; anthropology; emigration and immigration; Europe; humans; Iran; islands; Sicily; Spain; agriculture; DNA ancient; genome-wide association studyancientAgricultureDNAChalcolithicEmigration and Immigrationwestern mediterranean islands populationhumanitiesEuropeAncient DNA ; steppe ancestry ; western Mediterranean030104 developmental biologyAncient DNAGeographySpainAnthropologyAfricagovernmentancient-DNAEthnology030217 neurology & neurosurgeryGenome-Wide Association Study
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Genome-wide patterns of selection in 230 ancient Eurasians

2015

Mathieson, Iain et al.

MaleMultifactorial InheritanceArchaeogeneticsAsiaPopulationBiologyGenomeArticleBone and Bones03 medical and health sciences0302 clinical medicineHumansSelection GeneticeducationHistory AncientSelection (genetic algorithm)030304 developmental biologyGenetics0303 health scienceseducation.field_of_studyMultidisciplinaryNatural selectionancient DNA; prehistory; Eurasia; natural selectionGenome HumanPigmentationImmunityAgricultureDNASequence Analysis DNA15. Life on landBody HeightDiet3. Good healthEuropeGenetics PopulationAncient DNAHaplotypesEvolutionary biologyHuman genomeAdaptation030217 neurology & neurosurgery
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Ancient human genomes suggest three ancestral populations for present-day Europeans

2014

We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes1,2,3,4 with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians3, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these popula…

HistoryNeanderthalBiologíaPopulation DynamicsPresent dayGenoma humàGenome//purl.org/becyt/ford/1 [https]Basal (phylogenetics)Settore BIO/13 - Biologia ApplicataHistory AncientGeneticsPrincipal Component Analysiseducation.field_of_study0303 health sciencesGenomeMultidisciplinaryAncient DNA030305 genetics & heredityfood and beveragesAgricultureGenomics3. Good healthEuropeWorkforceCIENCIAS NATURALES Y EXACTASHumanArchaeogeneticsAsiaLineage (genetic)EUROPEOtras Ciencias BiológicasEuropean Continental Ancestry GroupPopulationSettore BIO/08 - ANTROPOLOGIAevolution; EuropeansGenomicsBiologyArticleWhite PeopleAncientGenètica de poblacions humanesHuman originsCiencias Biológicas03 medical and health sciencesHUMAN ORIGINSbiology.animalHumansANCIENT DNA//purl.org/becyt/ford/1.6 [https]educationQuantitative Biology - Populations and EvolutionDenisovan030304 developmental biologyGenetic diversityancient DNA modern DNA Europeans prehistoryGenome HumanPopulations and Evolution (q-bio.PE)biology.organism_classificationAncient DNAEvolutionary biologyFOS: Biological sciencesUpper PaleolithicHuman genomeGENOMICS
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The diverse genetic origins of a Classical period Greek army.

2022

Trade and colonization caused an unprecedented increase in Mediterranean human mobility in the first millennium BCE. Often seen as a dividing force, warfare is in fact another catalyst of culture contact. We provide insight into the demographic dynamics of ancient warfare by reporting genome-wide data from fifth-century soldiers who fought for the army of the Greek Sicilian colony of Himera, along with representatives of the civilian population, nearby indigenous settlements, and 96 present-day individuals from Italy and Greece. Unlike the rest of the sample, many soldiers had ancestral origins in northern Europe, the Steppe, and the Caucasus. Integrating genetic, archaeological, isotopic, …

EuropeWarfareMultidisciplinaryMilitary PersonnelArchaeologyGreeceClassical worldHumanshistorySettore BIO/08 - Antropologiaancient DNAancient warfareHistory AncientProceedings of the National Academy of Sciences of the United States of America
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Ancestry and demography and descendants of Iron Age nomads of the Eurasian Steppe

2017

During the 1st millennium before the Common Era (BCE), nomadic tribes associated with the Iron Age Scythian culture spread over the Eurasian Steppe, covering a territory of more than 3,500 km in breadth. To understand the demographic processes behind the spread of the Scythian culture, we analysed genomic data from eight individuals and a mitochondrial dataset of 96 individuals originating in eastern and western parts of the Eurasian Steppe. Genomic inference reveals that Scythians in the east and the west of the steppe zone can best be described as a mixture of Yamnaya-related ancestry and an East Asian component. Demographic modelling suggests independent origins for eastern and western g…

Gene FlowMale0301 basic medicineSteppePopulation geneticsHuman MigrationGenomic dataBiological anthropologyScience[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropologyDatasets as TopicGeneral Physics and AstronomyDNA MitochondrialWhite PeopleArticleGeneral Biochemistry Genetics and Molecular BiologyRussia03 medical and health sciencesAsian Peopleddc:590HumansEast AsiaHistory AncientTransients and MigrantsModels StatisticalMultidisciplinarygeography.geographical_feature_categoryHuman migrationbusiness.industryQGenetic VariationGeneral ChemistryGrasslandKazakhstan030104 developmental biologyGeographyIron AgeEthnologybusiness
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