6533b7d3fe1ef96bd126168c
RESEARCH PRODUCT
Reconstructing the deep population history of Central and South America
Anja FurtwänglerLevy FigutiBastien LlamasDouglas J. KennettEmilie BertoliniDavid ReichDavid ReichDavid ReichBrendan J. CulletonPontus SkoglundPontus SkoglundVeronica WesolowskiKeith M. PruferAlan CooperNick PattersonIosif LazaridisMarkus ReindelElsa Tomasto-cagigaoDaniel CorachThomas K. HarperTiago FerrazTiago FerrazJonas OppenheimerJonas OppenheimerRodrigo Elias OliveiraChuan-chao WangChuan-chao WangNathan NakatsukaNathan NakatsukaThiseas Christos LamnidisPeter KaulickeWolfgang HaakJohannes KrauseJohannes KrauseNicole AdamskiNicole AdamskiKelly M. HarkinsCláudia Regina PlensCésar MéndezNadin RohlandDomingo C. Salazar-garcíaDomingo C. Salazar-garcíaMario A. RiveraMario A. RiveraAlberto BarioniPaulo DeblasisNahuel A. ScheiflerAmalia Nuevo DelaunayLars Fehren-schmitzKaterina HarvatiKurt RademakerSahra TalamoElizabeth A. NelsonElizabeth A. NelsonClara ScabuzzoCosimo PosthCosimo PosthAndré StraussKathrin NägeleDanilo V. BernardoAnn Marie LawsonAnn Marie LawsonAndersen LiryoPablo Geronimo MessineoMark RobinsonJudith BeierGustavo G. PolitisEliane N. ChimSabine EggersSabine EggersMatthew FerryMatthew FerrySaid M. GutierrezJakob SedigLisiane Müller Plumm GomesMariana InglezNasreen BroomandkhoshbachtNasreen BroomandkhoshbachtKristin StewardsonKristin StewardsonTábita HünemeierSwapan MallickSwapan MallickSwapan MallickWilla R. TraskMarcony AlvesHugo Reyes-centenoStephan SchiffelsMichael FranckenMark HubbeMark HubbeMegan MichelMegan MichelJean-jacques Hublinsubject
0301 basic medicineGene Flow010506 paleontologyHistoryPopulationPopulationPopulation ReplacementBiology01 natural sciencesGenomeMedical and Health SciencesDNA MitochondrialGeneral Biochemistry Genetics and Molecular BiologyGene flowAncient03 medical and health sciencesTheoreticalModelsGeneticsHumansGENÉTICA DE POPULAÇÕESanthropologyIndis de l'Amèrica CentralDNA AncientTransecteducationHistory Ancient0105 earth and related environmental scienceseducation.field_of_studypopulation geneticGenomeGenome HumanHuman Genomepopulation geneticsarchaeologyCentral AmericaDNABiological SciencesSouth AmericaModels TheoreticalArchaeologyMitochondrial030104 developmental biologyAncient DNAGenetics PopulationDevelopmental BiologyHumandescription
We report genome-wide ancient DNA from 49 individuals forming four parallel time transects in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least ∼9,000 years ago. The common ancestral population radiated rapidly from just one of the two early branches that contributed to Native Americans today. We document two previously unappreciated streams of gene flow between North and South America. One affected the Central Andes by ∼4,200 years ago, while the other explains an affinity between the oldest North American genome associated with the Clovis culture and the oldest Central and South Americans from Chile, Brazil, and Belize. However, this was not the primary source for later South Americans, as the other ancient individuals derive from lineages without specific affinity to the Clovis-associated genome, suggesting a population replacement that began at least 9,000 years ago and was followed by substantial population continuity in multiple regions. A large-scale analysis of ancient genomes from Central and South America yields insights into the peopling of the Americas, including four southward population spreads and notable population continuity in much of South America after arrival.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-11-01 |