1210Long-term follow-up in the German TRAnscatheter mitral valve Interventions (TRAMI) registry: survival and predictors of mortality

P4730Underweight is associated with unfavourable short- and long-term outcomes after MitraClip therapy: a body mass index derived subgroup analysis of the German Transcatheter Mitral Valve Interventions (

Abstract Background Underweight and obesity represent classical risk factors for patients undergoing cardiac surgery or interventional treatment. The multicentre German Transcatheter Mitral Valve Interventions (TRAMI) registry comprises a large and prospectively enrolled real-world cohort of patients treated by MitraClip implantation. Aims The current analysis examines the impact of underweight, overweight and obesity on intra-hospital, short and long-term outcomes in patients treated by MitraClip therapy. Methods and results From 08/2010 until 07/2013, 799 patients (age 75.3±8.6 years, male gender 60.7%, median logistic EuroSCORE 20% [12; 31], functional mitral regurgitation (MR): 69.3%) w…

Impact of left atrial diameter on outcome in patients undergoing edge-to-edge mitral valve repair: results from the German TRAnscatheter Mitral valve Interventions registry (TRAMI)

Abstract Background Left atrium (LA) dimension is a marker of disease severity and outcome in primary and secondary mitral regurgitation. In transcatheter mitral valve repair LA enlargement might additionally impact on device handling and technical success through an altered anatomy and atrial annular dilatation. Methods Data from the multicenter German transcatheter mitral valve intervention registry “TRAMI” were used to analyse the association of baseline LA diameter by tertiles and efficacy, safety and long-term clinical outcome in patients undergoing edge-to-edge repair with the MitraClip. Results In 520 of 843 patients prospectively enrolled in TRAMI baseline LA diameter were reported …

Primär-Dilatation versus Thrombolyse bei Patienten mit akutem Myokardinfarkt, die nicht in randomisierte Studien eingeschlossen wurden

Die randomisierten Studien zum Vergleich der Thrombolyse und der Primar-Dilatation beim akuten Myokardinfarkt schlossen keine Patienten mit Linksschenkelblock, nichtdiagnostischem ersten Elektrokardiogramm, einer Prahospitalzeit von ≥ 12 h oder einer unbekannten Prahospitalzeit ein. Im klinischen Alltag werden jedoch haufig solche Patienten mittels Thrombolyse oder Primar-Dilatation behandelt. Um diese Patientengruppen zu beschreiben und den Einflus der Lyse und der Primar-Dilatation zu vergleichen, untersuchten wir die Daten aus der “Maximale Individuelle Optimierte Therapie beim Akuten Myokardinfarkt” (MITRA)-Studie. Bei 737 von 3308 (22,3 %) mittels Primar-Dilatation oder Lyse behandelte…