0000000000229188

AUTHOR

Cristina Ferrari

showing 4 related works from this author

Proceedings Of The 23Rd Paediatric Rheumatology European Society Congress: Part Two

2017

lcsh:Diseases of the musculoskeletal systemlcsh:RJ1-570lcsh:Pediatricslcsh:RC925-935Meeting Abstracts
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Radium-223 in mCPRC patients: a large real-life Italian multicenter study

2020

Background Radium-223 is a targeted alpha-particles therapy approved for the treatment of mCRPC patients with symptomatic bone metastases. To our knowledge we account for the largest cohort of mCRPC patients subjected to Radium-223 treatment in our country. We aim to describe in a real-life setting the largest cohort of mCRPC patients treated with Radium-223 ever taken into consideration. Methods 430 consecutive mCRPC patients were enrolled. Clinical data have been collected at baseline and at the end of the Radium-223 treatment. Furthermore, the overall survival(OS) of our population has been provided. Results 157 patients (36.5%) were still alive at the time of data analysis. A mean numbe…

MaleRadium-223radium-223; mCRPC; prostate cancer; target alpha therapyPediatricsmedicine.medical_specialtyradium-223UrologyPopulationBone NeoplasmsContext (language use)Quality of lifemedicineHumanseducationeducation.field_of_studybusiness.industrymCRPCprostate cancerProstatic Neoplasms Castration-ResistantRegimenSafety profileTreatment OutcomeItalyMulticenter studyNephrologyCohortQuality of LifeSettore SECS-S/01businesstarget alpha therapyRadiummedicine.drugMinerva Urology and Nephrology
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Epidemiology, Clinical Features and Prognostic Factors of Pediatric SARS-CoV-2 Infection: Results From an Italian Multicenter Study

2021

Background: Many aspects of SARS-CoV-2 infection in children and adolescents remain unclear and optimal treatment is debated. The objective of our study was to investigate epidemiological, clinical and therapeutic characteristics of pediatric SARS-CoV-2 infection, focusing on risk factors for complicated and critical disease.Methods: The present multicenter Italian study was promoted by the Italian Society of Pediatric Infectious Diseases, involving both pediatric hospitals and general pediatricians/family doctors. All subjects under 18 years of age with documented SARS-CoV-2 infection and referred to the coordinating center were enrolled from March 2020.Results: As of 15 September 2020, 75…

Pediatricsmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MIS-CDisease030204 cardiovascular system & hematologyPediatrics03 medical and health sciences0302 clinical medicinechildren030225 pediatricsEpidemiologymedicinebookOriginal Researchmultisystem inflammatory syndromeMIS-C COVID-19business.industrySARS-CoV-2 infectionDisease progressionlcsh:RJ1-570COVID-19lcsh:PediatricsSettore MED/38Icu admissionCOVID-19; MIS-C; SARS-CoV-2 infection; children; multisystem inflammatory syndromeMulticenter studyPediatrics Perinatology and Child HealthPediatric Infectious Diseasebook.journalbusiness
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Ki-67 immunoexpression and radiological assessment of necrosis improves accuracy of conventional and modified core biopsy systems in predicting the f…

2021

Based on the French Federation Nationale des Centers de Lutte Contre le Cancer (FNCLCC) grading system, this study assesses the accuracy of conventional and modified core biopsy (CB) systems in predicting the final grade (low vs high) assigned to the resected specimen. Substituting Ki-67 immunoexpression for mitotic count, and radiological for histological assessment of necrosis, we used two modified FNCLCC CB grading systems: (1) Ki-67 immunoexpression alone, and (2) Ki-67 plus radiological assessment of necrosis. We graded 199 soft tissue sarcomas (STS) from nine centers, and compared the results for the conventional (obtained from local histopathology reports) and modified CB systems wit…

AdultMalemedicine.medical_specialtySoft Tissue NeoplasmsPathology and Forensic MedicineRadiological necrosisNecrosisCore biopsymedicineBiomarkers TumorHumansGrading (education)Retrospective StudiesNot evaluatedReceiver operating characteristicbiologybusiness.industrySarcomasSoft tissueSarcomaCell Biologymedicine.diseaseKi-67 AntigenRadiological weaponKi-67biology.proteinKi-67HistopathologyFemaleSarcomaBiopsy Large-Core NeedleNuclear medicinebusinessFNCLCC grading system
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