0000000000229703
AUTHOR
Ignacio Ventura González
La biología celular de GPBP (Goodpasture antigen binding protein)
La enfermedad de Goodpasture (GP) es un proceso autoinmune exclusivamente humano caracterizado por una glomerulonefritis rápidamente progresiva y hemorragia pulmonar, causado por los autoanticuerpos que se depositan a lo largo de la membrana basal del glomérulo renal y el alveolo pulmonar. Los anticuerpos patógenos están dirigidos contra la región no-colagenosa del dominio C-terminal (NC1) de la cadena ¿3 del colágeno IV [a3 (IV)NC1 ] también llamado antígeno GP. Con el propósito de identificar proteínas que interaccionan con la región divergente N terminal del antígeno Goodpasture humano, se utilizaron de forma combinada un péptido sintético de 21 residuos que representa esta región y anti…
Cómo abordar el desarrollo de una competencia transversal compleja mediante el alineamiento constructivo
[EN] We present a model based on activities for the acquisition of essential competences of the scientific-technical qualifications, developed throughout the course of Cell Biology of the 1st year of the Degree in Biotechnology. For example, the search and analysis of bibliographic information and the design and interpretation of experiments are closely related and very important competences in the training of the biotechnologist, however they are not well contemplated in a specific way in the study plans. The proposed activities, designed under the premises of the constructive alignment of Biggs and Tang, develop these competences jointly and within the framework of a single subject.
Desarrollo de competencias profesionales en biomedicina utilizando el aprendizaje basado en proyectos
[EN] Professional competences in the field of experimental sciences are acquired through the practice of professional practice. In the university environment, the knowledge, skills and abilities in the different undergraduate subjects are taught in a parceled manner. Our 45 students biotechnology studies in Catholic University of Valencia, during the internship repeat protolocos and follow a recipe to perform an experiment that exemplifies the fundamental contents of the subject being taught. The aboradaje of this work is based on project-based learning. The student has to elaborate a biotechnological project from beginning to end. The project is based on the construction of a non-viral vec…