0000000000241176
AUTHOR
Begoña Fuster Escrivá
Impact of the SARS-CoV-2 Pandemic in Candidaemia, Invasive Aspergillosis and Antifungal Consumption in a Tertiary Hospital
In addition to the increase in fungal infections that has been observed in the last few decades, it has been reported that severe clinical COVID-19 can increase the risk of invasive fungal infections. The main objective of this study was to evaluate if there had been an increase in candidaemia and invasive pulmonary aspergillosis (IPA) cases since the onset of the SARS-CoV-2 pandemic. Data were retrospectively collected from April 2019 to March 2021, from patients admitted to Consorcio Hospital General Universitario de Valencia (Spain). A total of 152 candidaemia cases (56 of which were due to Candida auris) and 108 possible IPA cases were detected. A great increase in candidaemia cases was…
Caracterización de cepas de Klebsiella pneumoniae resistentes a carbapenems
Introducción: Klebsiella pneumoniae es un importante patógeno humano, tanto en el ambiente hospitalario como en la comunidad. Coloniza las mucosas y la piel de pacientes hospitalizados, causando sobre todo infecciones del tracto respiratorio y del tracto urinario. En personas con comorbilidades se comporta como un patógeno oportunista, especialmente en pacientes inmunocomprometidos. La rápida expansión de la resistencia a antibióticos carbapenémicos en K. pneumoniae, considerados antimicrobianos de última línea, se atribuye a la adquisición de enzimas con capacidad para hidrolizar estos antibióticos. Además, esta diseminación se ve facilitada por la existencia de elementos genéticos móviles…
“The effectiveness of rapid antigen test-based for SARS-CoV-2 detection in nursing homes in Valencia, Spain”
The usefulness of the PANBIOTM COVID-19 Ag rapid test for SARS-CoV-2 infection detection has not been widely studied, especially in specific population groups such as the elderly who are institutionalized. Rapid diagnostic tests have the potential to benefit testing strategies, as they have short turnaround times, they are cheap, simple to perform and can be used in decentralized testing. The objective of this study is to show the performance of the PANBIOTM COVID-19 Ag Rapid test device conducted at geriatric institutions and to compare results to those obtained from RT-PCR. A total of 448 individuals were enrolled in the study, including both residents and employees. Nasopharyngeal swabs …
The first wave of the Spanish COVID-19 epidemic was associated with early introductions and fast spread of a dominating genetic variant
The COVID-19 pandemic has shaken the world since the beginning of 2020. Spain is among the European countries with the highest incidence of the disease during the first pandemic wave. We established a multidisciplinar consortium to monitor and study the evolution of the epidemic, with the aim of contributing to decision making and stopping rapid spreading across the country. We present the results for 2170 sequences from the first wave of the SARS-Cov-2 epidemic in Spain and representing 12% of diagnosed cases until 14th March. This effort allows us to document at least 500 initial introductions, between early February-March from multiple international sources. Importantly, we document the …