0000000000260972
AUTHOR
Carmen Gavaldá-esteve
Retinoids and proliferative verrucous leukoplakia (PVL). A preliminary study.
Objective. A study is made of the efficacy and adverse effects of retinoid therapy applied to the white lesions of proliferative verrucous leukoplakia (PVL). Material and methods. The results of retinoid therapy were evaluated in 17 patients diagnosed with PVL. Topical retinoids were used in 5 patients, in the form of two daily applications of 0.1% 13-cis-retinoic acid in orabase for an average of 6.17+/-3.13 months. Systemic retinoids were used in 11 patients, with the administration of 25 mg/day of acitretin in tablet form for an average of 5.41+/-2.02 months. One patient successively received the topical and systemic retinoid formulations. The course and results were evaluated on a blind…
Dental management of patients receiving anticoagulant and/or antiplatelet treatment
Introduction: Adequate hemostasis is crucial for the success of invasive dental treatment, since bleeding problems can give rise to complications associated with important morbidity-mortality. The dental treatment of patients who tend to an increased risk of bleeding due to the use of anticoagulant and/or antiplatelet drugs raises a challenge in the daily practice of dental professionals. Adequate knowledge of the mechanisms underlying hemostasis, and the optimized management of such patients, are therefore very important issues. Objectives: A study is made of the anticoagulant / antiplatelet drugs currently available on the market, with evaluation of the risks and benefits of suspending su…
Eritema multiforme: Revisión y puesta al día
El sistema multiforme es una enfermedad de la piel y las mucosas que se manifiesta con lesiones eritematosas y de tipo vesiculo-ampollar. Las lesiones vesiculo-ampollares y erosivas a nivel de la cavidad oral y la piel pueden ser vausadas por un amplio grupo de patologias. La etiologia de la mismas tambien puede ser muy variable, desde una causa traumatica o quimica por contacto, hasta una causa autoinmune. Dado que en ocasiones es dificil hacer un diagnostico diferencial para discernir la etiologia de las lesiones, es importante conocer los detalles clinicos y los aspectos epidemiologicos e histopatologicos de cada una de ellas. En este articulo se hace una revision de los aspectos epidemi…
Oxidative stress in bisphosphonate-related osteonecrosis of the jaws
Objectives To analyze whether oxidative stress (OS) changes are present in patients with bisphosphonate-related osteonecrosis of the jaw (BRONJ) versus controls. Materials and Methods Oxidative stress was analyzed in serum and unstimulated saliva of three groups: Group 1 consisted of 24 patients who had been treated with intravenous bisphosphonates (ivBPs) and developed BRONJ, group 2 consisted of 20 patients who had received ivBPs and did not develop BRONJ, and group 3 comprised 17 control subjects. Reduced glutathione (GSH), malondialdehyde (MDA), oxidized glutathione (GSSG), and 8–oxo-7,8-dihydro-2-deoxyguanosine (8-oxo-dG) levels, as well as the GSSG/GSH ratio, were measured. Results Me…