0000000000272867

AUTHOR

Siragusa A

Enhanced efficiency of organic light emitting diodes by NaOH surface treatment of indium tin oxide anode

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TERAPIA DI II LINEA NEL CARCINOMA PROSTATICO ORMONOREFRATTARIO (HRPC) CON ESTRAMUSTINA FOSFATO ED ETOPOSIDE. STUDIO DI FASE II DEL GSTU

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Differential expression of proteolytic enzymes during epithelial-mesenchymal transaction of endothelial cells.

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Oral chemotherapy in hormone-refractory prostate carcinoma patients unwilling to be admitted to hospital.

<i>Objectives:</i> To investigate the safety and efficacy in terms of PSA response of a low-dose oral combination of estramustine phosphate (EMP) and etoposide (VP16) in hormone- refractory prostate cancer (HRPC) patients. Well-tolerated outpatient chemotherapy regimens for patients unfit and/or unwilling to be admitted to hospital are needed. <i>Methods:</i> Fifty-six HRPC patients with metastatic disease (median age 75 years) were randomized between arm A (daily oral EMP 10 mg/kg, in 3 doses) and arm B (28-day cycle with low-dose EMP 3 mg/kg once daily plus VP16 25 mg/m<sup>2</sup> once daily on days 1 through 14). Baseline characteristics between the t…

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ESTRAMUSTINA FOSFATO VS ASSOCIAZIONE A BASSA DOSE DI ESTRAMUSTINA FOSFATO E ETOPOSIDE NEL CARCINOMA PROSTATICO ORMONOREFRATTARIO (HRPC). STUDIO RANDOMIZZATO DI FASE II DEL GRUPPO STUDI TUMORI UROLOGICI (GSTU)

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Ruolo della terapia di mantenimento e fattori di rischio ambientale nel carcinoma vescicale superficiale. Pazienti sottoposti a chemioterapia endovescicale adiuvante. Risultati preliminari di uno studio randomizzato su 577 pazienti.

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Chemioterapia domiciliare nel carcinoma prostatico ormonorefrattario (HRPC). Studio di fase II del gruppo studio tumori urologici (GSTU).

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Terapia orale domiciliare per il paziente con il carcinoma prostatico ormonorefrattario.

TERAPIA ORALE DOMICILIARE PER IL PAZIENTE CON CARCINOMA PROSTATICO ORMONOREFRATTARIO V. Altieri, V. Serretta, D. Melloni, R. Allegro, G. Morgia, M. Madonia, M. Ferro, A. Siragusa, G. De Grande, L. Orestano, M. Napoli, E. Membri Fondazione GSTU (Napoli) SCOPO DEL LAVORO: Per preservare la qualità di vita del paziente affetto da carcinoma prostatico ormonorefrattario (HRPC) si rendono necessari regimi terapeutici che possano essere eseguiti a domicilio senza frequenti ricoveri ospedalieri, seppur in regime di dayhospital. I vantaggi in termini di sopravvivenza offerti da schemi chemioterapici a base di taxani, pur presenti, sono ad oggi limitati. Scopo del presente studio di fase II è stato q…

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ESTRAMUSTINA FOSFATO VS ASSOCIAZIONE A BASSA DOSE DI ESTRAMUSTINA FOSFATO ED ETOPOSIDE NEL CARCINOMA PROSTATICO ORMONOREFRATTARIO. STUDIO RANDOMIZZATO IN FASE II DEL GRUPPO STUDI TUMORI UROLOGICI (GSTU)

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Attività lavorativa e fattori di rischio ambientale in pazienti affetti da carcinoma vescicale superficiale.

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ESTRAMUSTINE PHOSPATE VERSUS INTERMITTENT LOW DOSE ORAL COMBINATION OF ESTRAMUSTINE PHOSPATE AND ETOPOSIDE IN HORMONE REFRACTORY PROSTATE CARCINOMA. A PHASE II STUDY OF GSTU FOUND.

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low dose oral chemotherapy for hormone refractory prostate carcnoma.Estramustine phosphate versus estramustine phosphate and etoposide. A randomised phase II study of GSTU Found.

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Out-patient low-dose oral chemotherapy in hormone refractory prostate carcinoma (HRPC) patients unfit for hospital admittance.

Objectives: Well tolerated out-patient regimens for HRPC chemotherapy in elderly patients with geographical difficulties and/or unwilling hospital admission are needed. The aim of the present study was to investigate the safety and efficacy of a low-dose oral combination of estramustine phosphate (EMP) and etoposide (VP16). Patients: Fifty-six HRPC patients, median age 75 years, were randomized between daily EMP (10mg/kg) – arm A, and low-dose EMP (3mg/kg) plus VP16 (25mg/mq) 2 weeks monthly – arm B. Randomization ratio was 2:3. Median PSA was 41.1 ng/ml. Baseline characteristics between the 2 groups were similar. LHRH therapy was maintained. Antiandrogen was stopped one month before entry.…

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A randomized phase II study of estramustine phosphate versus estramustine phosphate plus etoposide in hormone refractory prostate cancer (HRPC)

20632 Background: Docetaxel-based regimens represent the treatment of choice of HRPC. However, in some patients toxicity may be a concern and the quality of life may be compromised. The aim of this phase II randomized study is to investigate the efficacy and safety of low-dose chemotherapy regimen adopting a combination of EMP and VP16 in patients affected by HRPC. Methods: 54 HRPC patients were randomized between: arm A, daily oral standard dose EMP (10mg/kg) and arm B, low-dose EMP (3mg/kg) plus VP16 (25mg/mq) for 2 weeks followed by 2-weeks’rest. Systemic toxicity and hematologic exams were monitored every 2 weeks. Performance status, pain and analgesic use were evaluated according to WH…

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LED organici con emissione nel blu

We report the development of blue organic light emitting diodes (OLEDs) based on molecular materials. Electrical characteristics and quantum efficiency of single layer devices and triple layer devices comprising further a hole blocking layer and an electron injection layer are compared and prospects for applications to passive matrix displays and fluorescence integrated biosensors are also discussed.

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