0000000000285278

AUTHOR

G. Faupel

showing 2 related works from this author

Double-Blind Study on the Effects of Steroids on Severe Closed Head Injury

1976

The results of a double-blind study on the effects of a low dose and a high dose of dexamethasone on severe closed head injury are presented. The steroid, particularly in high dose, reduced mortality, improved the neurologic course and the final outcome. Timing of steroid administration is of great importance.

Double blind studySevere head injurybusiness.industryBrain edemaAnesthesiaClosed head injuryHead injuryLow doseMedicinebusinessmedicine.diseaseDexamethasonemedicine.drug
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Dexamethasone in severe head injuries

1979

The results of a double-blind-study on the effects of placebo, a low dose and a high dose of dexamethasone on severe closed head injury are presented. 95 patients were selected and carefully analyzed according to mortality, neurological course and symptoms, midbrain lesions and final outcome. The results demonstrate that dexamethasone, particularly given in high doses, reduces mortality and improves the neurological course. The steroid treatment seems to improve chances as well as quality of survival. Apart from the dose, timing of administration is of great importance.

medicine.medical_specialtySevere head injurybusiness.industryLow doseGeneral Medicinemedicine.diseasePlaceboSteroid therapyAnesthesiaClosed head injurymedicineHigh dosesSurgeryNeurology (clinical)NeurosurgerybusinessDexamethasonemedicine.drugNeurosurgical Review
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