6533b7d6fe1ef96bd1266e38

RESEARCH PRODUCT

Double-Blind Study on the Effects of Steroids on Severe Closed Head Injury

K. SchürmannD. MüllerH. J. ReulenG. Faupel

subject

Double blind studySevere head injurybusiness.industryBrain edemaAnesthesiaClosed head injuryHead injuryLow doseMedicinebusinessmedicine.diseaseDexamethasonemedicine.drug

description

The results of a double-blind study on the effects of a low dose and a high dose of dexamethasone on severe closed head injury are presented. The steroid, particularly in high dose, reduced mortality, improved the neurologic course and the final outcome. Timing of steroid administration is of great importance.

https://doi.org/10.1007/978-3-642-66524-0_52