0000000000291290

AUTHOR

H. Ito

showing 8 related works from this author

Observation of Coulomb-assisted nuclear bound state of $��^-$-$^{14}$N system

2020

In an emulsion-counter hybrid experiment performed at J-PARC, a $��^-$ absorption event was observed which decayed into twin single-$��$ hypernuclei. Kinematic calculations enabled a unique identification of the reaction process as $��^{-} + ^{14}$N$\ \rightarrow\ ^{10}_��$Be + $^5_��$He. For the binding energy of the $��^{-}$ hyperon in the $��^-$-$^{14}$N system a value of $1.27 \pm 0.21$ MeV was deduced. The energy level of $��^-$ is likely a nuclear $1p$ state which indicates a weak $��N$-$����$ coupling.

FOS: Physical sciencesNuclear Experiment (nucl-ex)
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Large-scale genotyping identifies 41 new loci associated with breast cancer risk

2013

Journal article Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We report here a meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, from which we selected 29,807 SNPs for further genotyping. These SNPs were genotyped in 45,290 cases and 41,880 controls of European ancestry from 41 studies in the Breast Cancer Association Consortium (BCAC). The SNPs were genotyped as part of a collaborative genotyping experiment involving four consortia (Collaborat…

signaling pathwayGenotypingGenotypeSingle-nucleotide polymorphismGenome-wide association studyBreast NeoplasmsconsortiumBiologyBreast Neoplasms; Case-Control Studies; Cooperative Behavior; Female; Gene-Environment Interaction; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Meta-Analysis as Topic; Polymorphism Single Nucleotide; Risk Factors; Genetic Predisposition to Disease; GeneticsPolymorphism Single NucleotideArticle03 medical and health sciences0302 clinical medicineBreast cancerSDG 3 - Good Health and Well-beingMeta-Analysis as TopicRisk FactorsGenotypecommon variantsexpressionGeneticsmedicineHumansGenetic Predisposition to DiseasePolymorphismCooperative BehaviorgeneGenotypinghormone-related protein030304 developmental biologyGenetic associationGenetics0303 health sciencesBreast cancer susceptibilityCancerSingle Nucleotidemedicine.diseaseconfer susceptibilitysusceptibility loci3. Good health14q24.1 rad51l1TOX3Genetic Loci030220 oncology & carcinogenesisCase-Control Studiesgenome-wide associationFemaleGene-Environment InteractionGenome-Wide Association Study
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Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.

2014

Previous studies have suggested that polymorphisms in CASP8 on chromosome 2 are associated with breast cancer risk. To clarify the role of CASP8 in breast cancer susceptibility, we carried out dense genotyping of this region in the Breast Cancer Association Consortium (BCAC). Single-nucleotide polymorphisms (SNPs) spanning a 1 Mb region around CASP8 were genotyped in 46 450 breast cancer cases and 42 600 controls of European origin from 41 studies participating in the BCAC as part of a custom genotyping array experiment (iCOGS). Missing genotypes and SNPs were imputed and, after quality exclusions, 501 typed and 1232 imputed SNPs were included in logistic regressionmodels adjusting for stud…

Genotyping TechniquesResearch Support U.S. Gov't P.H.S.CASP8 and FADD-Like Apoptosis Regulating ProteinGenome-wide association studyP.H.S.Medical and Health SciencesBreast and Ovarian Cancer Susceptibility (BOCS) StudyMedizinische FakultätGenetics(clinical)Non-U.S. Gov'tGenetics (clinical)GeneticsGenetics & HeredityvariantsCaspase 8Research Support Non-U.S. Gov'tAssociation Studies ArticlesGeneral MedicineBiological Sciencesddc:Chromosomes Human Pair 2kConFab InvestigatorsFemaleGENICA NetworkAustralian Ovarian Cancer Study GroupEuropean Continental Ancestry GroupNon-P.H.S.Single-nucleotide polymorphismBreast Neoplasms-BiologyResearch SupportPolymorphism Single NucleotideWhite PeopleN.I.H.Breast cancerResearch Support N.I.H. ExtramuralSDG 3 - Good Health and Well-beingmedicineGeneticsJournal ArticleHumansGenetic Predisposition to Diseaseddc:610geneGenotyping TechniquesGenotypingMolecular BiologyGenetic associationdiseaseExtramuralProteinsOdds ratiomedicine.diseasesusceptibility lociMinor allele frequencyCase-Control Studiesgenome-wide associationenhancersU.S. Gov'tcasp8Research Support U.S. Gov't Non-P.H.S.Genome-Wide Association Study
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Worldwide comparison of ovarian cancer survival: Histological group and stage at diagnosis (CONCORD-2)

2016

Abstract Objective Ovarian cancer comprises several histological groups with widely differing levels of survival. We aimed to explore international variation in survival for each group to help interpret international differences in survival from all ovarian cancers combined. We also examined differences in stage-specific survival. Methods The CONCORD programme is the largest population-based study of global trends in cancer survival, including data from 60 countries for 695,932 women (aged 15–99years) diagnosed with ovarian cancer during 1995–2009. We defined six histological groups: type I epithelial, type II epithelial, germ cell, sex cord-stromal, other specific non-epithelial and non-sp…

0301 basic medicineOncologySettore MED/42 - Igiene Generale E Applicata0302 clinical medicinemorphology80 and overStage (cooking)Aged 80 and overOvarian Neoplasmseducation.field_of_studyepidemiology; histology; morphology; ovarian cancer; stage; survival; Adolescent; Adult; Aged; Aged 80 and over; Female; Humans; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Oncology; Obstetrics and GynecologyObstetrics and Gynecologyepidemiology; histology; morphology; ovarian cancer; stage; survivalMiddle AgedTransitional cell carcinomaovarian cancerOncology030220 oncology & carcinogenesisClear cell carcinomaepidemiologyFemaleHumanAdultmedicine.medical_specialtyAdolescentPopulationSocio-culturalesurvivalArticlehistology03 medical and health sciencesInternal medicinemedicineHumansovarian cancer epidemiology survival stage morphology histologyeducationepidemiology ; histology ; morphology ; ovarian cancer ; stage ; survivalCancer stagingAgedNeoplasm StagingGynecologybusiness.industryOvarian NeoplasmCancermedicine.diseasestageCancer registry030104 developmental biologyOvarian cancerbusiness
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Worldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual…

2017

BACKGROUND: Global inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess worldwide differences and trends in population-based cancer survival. In this population-based study, we aimed to estimate survival inequalities globally for several subtypes of childhood leukaemia. METHODS: Cancer registries participating in CONCORD were asked to submit tumour registrations for all children aged 0-14 years who were diagnosed with leukaemia between Jan 1, 1995, and Dec 31, 2009, and followed up until Dec 31, 2009. Haematological malignancies were defined by morphology codes in the International Classification of Diseases for …

childhood leukaemiaCancer registrieleukemiacancerchildhood cancerSocio-culturaleHematologySettore MED/42 - Igiene Generale E ApplicataHematology childhood leukaemia cancer survivalcancer survival
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Observation of Coulomb-assisted nuclear bound state of $\Xi^-$-$^{14}$N system

2020

In an emulsion-counter hybrid experiment performed at J-PARC, a $\Xi^-$ absorption event was observed which decayed into twin single-$\Lambda$ hypernuclei. Kinematic calculations enabled a unique identification of the reaction process as $\Xi^{-} + ^{14}$N$\ \rightarrow\ ^{10}_\Lambda$Be + $^5_\Lambda$He. For the binding energy of the $\Xi^{-}$ hyperon in the $\Xi^-$-$^{14}$N system a value of $1.27 \pm 0.21$ MeV was deduced. The energy level of $\Xi^-$ is likely a nuclear $1p$ state which indicates a weak ${\Xi}N$-$\Lambda\Lambda$ coupling.

Nuclear ExperimentNuclear Experiment
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CCDC 894775: Experimental Crystal Structure Determination

2013

Related Article: L.Pilia,E.Sessini,F.Artizzu,M.Yamashita,A.Serpe,K.Kubo,H.Ito, H.Tanaka,S.Kuroda,J.Yamada,P.Deplano,C.J.Gomez-Garcia,M.L.Mercuri|2013|Inorg.Chem.|52|423|doi:10.1021/ic302234j

Space GroupCrystallographyCrystal SystemCrystal Structurehexakis(25-bis(13-Dithiolan-2-ylidene)-1346-tetrathiapentalene) tris(345-trioxocyclopentene-12-diolato)-gallium dichloromethane solvateCell ParametersExperimental 3D Coordinates
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CCDC 894774: Experimental Crystal Structure Determination

2013

Related Article: L.Pilia,E.Sessini,F.Artizzu,M.Yamashita,A.Serpe,K.Kubo,H.Ito, H.Tanaka,S.Kuroda,J.Yamada,P.Deplano,C.J.Gomez-Garcia,M.L.Mercuri|2013|Inorg.Chem.|52|423|doi:10.1021/ic302234j

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parametershexakis(25-bis(13-Dithiolan-2-ylidene)-1346-tetrathiapentalene) tris(345-trioxocyclopentene-12-diolato)-iron(iii) dichloromethane solvateExperimental 3D Coordinates
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