0000000000293328

AUTHOR

Annette Mika-grüttner

showing 4 related works from this author

The course of corticofacial projections in the human brainstem.

2001

Transcranial magnetic stimulation was used to investigate the corticofacial projections in 53 patients with (n = 28) and without (n = 25) central facial paresis due to unifocal ischaemic lesions at different brainstem levels. Lesion topography documented by MRI studies was correlated with the electrophysiological findings. In the majority of patients the corticofacial fibres travel within the ventromedial base of the pons and cross the midline at the level of the facial nucleus. In some individuals, however, we found evidence that corticolingual fibres form an 'aberrant bundle' in a paralemniscal position at the dorsal edge of the pontine base. In other patients the corticofacial fibres loo…

Cerebral CortexPontine Basebusiness.industryPyramidal TractsAnatomymedicine.diseaseFacial nerveMagnetic Resonance ImagingPonsFacial paralysisElectric StimulationLesionFacial NerveMagneticsmedicineHumansNeurology (clinical)Brainstemmedicine.symptombusinessMedullaParesisBrain StemBrain : a journal of neurology
researchProduct

Seventh nerve palsies may be the only clinical sign of small pontine infarctions in diabetic and hypertensive patients

2002

Backgroud: Small brainstem infarctions are increasingly recognized as a cause of isolated ocular motor and vestibular nerve palsies in diabetic and/or hypertensive patients. This raises the question whether there are also isolated 7th nerve palsies due to pontine infarctions in patients with such risk factors for the development of cerebrovascular diseases. Methods: Over an 11-year-period, we retrospectively identified 10 diabetic and/or hypertensive patients with isolated 7th nerve palsies and electrophysiological abnormalities indicating pontine dysfunction. All patients had examinations of masseter and blink reflexes, brainstem auditory evoked potentials, direct current electro-oculograp…

AdultMalemedicine.medical_specialtyBrain Stem InfarctionsNeurologyFunctional LateralityDiabetes ComplicationsOcular Motility DisordersPonsInternal medicineNeural PathwaysDiabetes MellitusVestibulocochlear Nerve DiseasesmedicineHumansCranial nerve diseaseStrokeAgedRetrospective StudiesParesisbusiness.industryMiddle AgedVestibular nervemedicine.diseaseMagnetic Resonance ImagingFacial nerveFacial paralysisSurgeryFacial NerveNeurologyBasilar ArteryHypertensionCardiologyFemaleDisease SusceptibilityNeurology (clinical)Facial Nerve Diseasesmedicine.symptombusinessJaw jerk reflexJournal of Neurology
researchProduct

Spontanes Liquorunterdrucksyndrom

1999

Wir berichten 11 Patienten mit orthostatischem Kopfschmerz bei spontanem Liquorunterdrucksyndrom (SLUDS). Ubelkeit und Abduzensparesen (bei 3 bzw. 2 Patienten) waren die haufigsten zusatzlichen Symptome. Zehn Patienten hatten eine Pleozytose (6 bis 43 Zellen/μl) und/oder Eiweiserhohung (581 bis 1668 mg/l) im Liquor. Die CT und/oder MRT zeigte bei 5 Patienten bifrontal betonte subdurale Hamatome oder Hygrome, die MRT bei allen 4 untersuchten Patienten eine diffuse Gadolinium-Aufnahme der Meningen, bei einem mit Kaudalverlagerung des Hirntammes. Liquorszintigraphisch (9 untersuchte Patienten) war immer ein fruher Tracer-Nachweis in der Blase und eine verminderte oder fehlende Aktivitat uber d…

GynecologyPsychiatry and Mental healthmedicine.medical_specialtyNeurologybusiness.industryMedicineNeurology (clinical)General MedicinebusinessDer Nervenarzt
researchProduct

The risk of abducens palsy after diagnostic lumbar puncture.

2000

Abducens palsy occasionally has been observed after diagnostic lumbar puncture (DLP).1-3 Its risk is not exactly known. We are aware of only one report, which mentions not a single case among 1,341 DLPs when using 22-gauge needles.4 At our clinic, an average of 800 inpatients a year undergo DLP. We usually use 22-gauge needles, and occasionally (in less than 5%), 20-gauge needles. Over a 14.5-year period, we saw two patients with abducens palsy—one unilateral, one bilateral—after DLP. This translates to a risk of less than 1 out of 5,800 DLPs. ### Patient 1. A 61-year-old man with type 2 diabetes noticed progressive weakness of the legs. Neurologic examination revealed proximal paraparesis,…

AdultMalemedicine.medical_specialtyWeaknessEye diseaseSpinal PunctureLumbarRisk FactorsParalysisMedicineCranial nerve diseaseHumansParalysisAbducens nervebusiness.industryBrainAbducens palsyMiddle Agedmedicine.diseaseMagnetic Resonance ImagingSurgeryNeurology (clinical)medicine.symptombusinessComplicationAbducens Nerve DiseasesNeurology
researchProduct