Diagnosis and therapy of cutaneous and mucocutaneous Leishmaniasis in Germany

The incidence of cutaneous and mucocutaneous Leishmaniasis (CL/MCL) is increasing globally, also in Germany, although the cases are imported and still low in number. The current evidence for the different therapies has many limitations due to lack of sufficient studies on the different Leishmania species with differing virulence. So far there is no international gold standard for the optimal management. The aim of the German joint working group on Leishmaniasis, formed by the societies of Tropical Medicine (DTG), Chemotherapy (PEG) and Dermatology (DDG), was to establish a guideline for the diagnosis and treatment of CL and MCL in Germany, based on evidence (Medline search yielded 400 artic…

Saccharomyces boulardii to Prevent Antibiotic-Associated Diarrhea: A Randomized, Double-Masked, Placebo-Controlled Trial.

Antibiotic-associated diarrhea is an important clinical problem, associated with morbidity, mortality and healthcare costs. Our randomized, placebo controlled multicenter trial do not support the efficacy of Saccharomyces boulardii in the prevention of antibiotic-associated diarrhea.

S1-Leitlinie Diagnostik und Therapie der kutanen und mukokutanen Leishmaniasis in Deutschland

DD ″Creeping eruption″

Unter dem Begriff ″creeping eruption″ werden verschiedene Infektionen oder Infestationen gefuhrt. Hierunter fallen zum Beispiel wandernde subkutane Schwellungen mit Rotung und Urtikaria bei Gnathostomiasis, kutaner Paragonimiasis (Lungenegelinfektion) oder Fasziolose (Leberegelinfektion). Ahnliche wandernde Symptome sind auch bei Befall mit Fliegenmaden (″migratory myiasis″) moglich. Nicht alle derart bezeichneten Erkrankungen haben einen unmittelbaren Bezug zu Hauterscheinungen.