6533b7dafe1ef96bd126d9a5

RESEARCH PRODUCT

Saccharomyces boulardii to Prevent Antibiotic-Associated Diarrhea: A Randomized, Double-Masked, Placebo-Controlled Trial.

Tom SchabergMartin KeuchelSandra LiggesNan GuoStefanie SchoppenAndreas De WeerthAnsgar W. LohseStefan SchmiedelJürgen MayMaximilian Philipp SchroederRebecca HinzMarkus ReiserGerd D. BurchardAndreas LangeheineckeEmil C. ReisingerRalf Matthias HagenStephan EhrhardtMarcus SchuchmannMaria Eveslage

subject

0301 basic medicinemedicine.medical_specialty030106 microbiologyPopulationPlacebo-controlled studyPlacebolaw.inventionMajor Articles03 medical and health sciences0302 clinical medicineRandomized controlled triallawInternal medicinemedicineAdverse effecteducationeducation.field_of_studybiologybusiness.industrybiology.organism_classificationClostridium difficile-associated diarrheaDiscontinuationSurgerySaccharomyces boulardiiInfectious DiseasesOncologyantibiotic-associated diarrhearandomized controlled trial030211 gastroenterology & hepatologyAntibiotic-associated diarrheabusinessprobioticSaccharomyces boulardii

description

Antibiotic-associated diarrhea is an important clinical problem, associated with morbidity, mortality and healthcare costs. Our randomized, placebo controlled multicenter trial do not support the efficacy of Saccharomyces boulardii in the prevention of antibiotic-associated diarrhea.

10.1093/ofid/ofw011https://pubmed.ncbi.nlm.nih.gov/26973849