0000000000303419
AUTHOR
Rainer Rupprecht
Drumming signals within the family Taeniopterygidae (Plecoptera)
Drumming signals of the 11 species of Palaearctic Taeniopterygidae are described for the first time based on the study of populations from nine different European countries from Spain to Russia. In this way, a contribution is made to our knowledge of the constancy respectively the divergence of signals typical for the species distributed over a very wide area. Communication patterns of the family under varying temperatures were analysed. The dependence on temperature indicates that the adults of this family are cold stenothermic insects. Within the genus Brachyptera (Newport, 1851), the call signal of males is significantly different from their response signal (duration and drumming frequen…
Zu den Ursachen der unterschiedlichen pH-Empfindlichkeit vonGammarus pulex L., G.fossarum KOCH (Amphipoda) undAselus aquaticus L. (Isopoda)
By means of ion chromatography the extensive and significantly higher loss of ions of G. pulex and G. fossarum in acid water (pH 3.0) as compared to neutral water is proved. While cations are being accumulated in the water, some ions (Na+, Cl−) leave the hemolymph in important percentage, others increase highly after being set free from the cells (K+ and Ca2+). The loss of cations with Asellus aquaticus in acid water (pH 3) is clearly lower than with Gammarus, and it is not significantly higher than when the animals are put into neutral water.
Antidepressants and Antipsychotic Drugs Colocalize with 5-HT(3) Receptors in Raft-Like Domains
Despite different chemical structure and pharmacodynamic signaling pathways, a variety of antidepressants and antipsychotics inhibit ion fluxes through 5-HT3receptors in a noncompetitive manner with the exception of the known competitive antagonists mirtazapine and clozapine. To further investigate the mechanisms underlying the noncompetitive inhibition of the serotonin-evoked cation current, we quantified the concentrations of different types of antidepressants and antipsychotics in fractions of sucrose flotation gradients isolated from HEK293 (human embryonic kidney 293) cells stably transfected with the 5-HT3Areceptor and of N1E-115 neuroblastoma cells in relation to the localization of …
Die bauchblase von Nemurella picteti klapalek (Insecta, Plecoptera)
1. Die Bauchblase von Nemurella ist eine mediane Ausbuchtung des 9. Abdominalsternums. Sie kommt nur bei den ♂♂ vor. 2. Ventral und lateral sitzen nach den elektronenmikroskopischen Untersuchungen mechanorezeptorische Sinneshaare. 3. Zu jedem Haar gehoren eine bipolare Sinneszelle und jeweils drei Hullzellen. Unterhalb der Basis des Tubularkorpers ragt eine Verstarkungsrippe der cuticularen Scheide nach innen. Diese durfte dazu dienen, bei Reizung ein Ausweichen des Tubularkorpers nach unten zu verhindern. 4. Die Morphologie der Haare und ihre einheitliche Anordnung auf der Ventralseite in Langsrichtung der Bauchblase stimmen uberein mit der Beobachtung, das die Bauchblase zum Trommeln verw…
Attempts to re-colonise water insects in German brooks
Attempts were made to reintroduce water insects (five stonefly species and one mayfly species) into several third order streams in Rhineland-Palatine and Hessen, Germany. All these streams had been strongly affected by waste water and rubbish and had lost most of their macroinvertebrates. As a consequence of the installation of several purification plants in the past three decades, water quality has improved. Since no stoneflies returned, 700–1300 eggs of three different species (Isoperla goertzi, I. oxylepis, and I. grammatica) were exposed in the Selz brook (1997). In February 1998 a few larvae and in 1999 about 10,000 eggs of Perla marginata were added in the Walluf brook, and in 1998, 5…
The drumming of the Plecoptera (Insecta)
1. Bei den trommelnden Perliden trommeln nicht nur die Mannchen, sondern auch die Weibchen. 2. Das Trommeln der Mannchen dient der Erkennung und Auffindung der Weibchen, die nur im unbegatteten Zustand das Trommeln erwidern. 3. Das Mannchen trommelt immer zuerst, das Weibchen antwortet sofort danach. Bei Capnia, Perla und Dinocras sucht nur das Mannchen, das Weibchen bleibt auf seinem Platz sitzen, wahrend bei Isoperla sich beide Geschlechter gegenseitig suchen und beim Zusammentreffen trommeln. 4. Nach der ersten Kopulation trommeln die Weibchen nicht mehr und beginnen mit dem Legen von Eiern, die sie sonst uber Tage und Wochen zuruckhalten. 5. Werden die begatteten Weibehen zufallig von e…
Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptor
Antidepressants are commonly supposed to enhance serotonergic and/or noradrenergic neurotransmission by inhibition of neurotransmitter reuptake through binding to the respective neurotransmitter transporters or through inhibition of the monoamine oxidase. Using the concentration-clamp technique and measurements of intracellular Ca2+, we demonstrate that different classes of antidepressants act as functional antagonists at the human 5-HT3A receptor stably expressed in HEK 293 cells and at endogenous 5-HT3 receptors of rat hippocampal neurons and N1E-115 neuroblastoma cells. The tricyclic antidepressants desipramine, imipramine, and trimipramine, the serotonin reuptake inhibitor fluoxetine, t…
A respiratory hemocyanin from an insect.
Insects possess an elaborate tracheal system that enables transport of gaseous oxygen from the atmosphere directly to the inner organs. Therefore, the presence of specialized oxygen-transport proteins in the circulatory system of insects has been considered generally unnecessary. Here, we show for the first time, to our knowledge, the presence of an ancestral and functional hemocyanin (Hc) in an insect. In the hemolymph of nymphs and adults of the stonefly Perla marginata , a hexameric Hc was identified, which consists of two distinct subunit types of 659 and 655 amino acids. P. marginata Hc displays cooperative oxygen binding with a moderately high oxygen affinity [(half-saturation pressu…
„Trommeln” als Verständigungsmittel bei Steinfliegen (Plecoptera)
Männchen und unbefruchtete Weibchen verschiedener Perlidenarten verständigen sich durch Trommeln. Die Frequenz der Trommelstöße wird bei Capnia bifrons und Perla marginata bestimmt. Die Übertragung des Trommelstoßes erfolgt nicht durch Schall (auf dem Luftwege), sondern durch die Erschütterung der Unterlage. Nicht nur diese drei Arten, deren Trommeln bei den Männchen schon früher beschrieben wurde, sondern auch Perla marginata und Isoperla grammatica erzeugen in gleicher Weise Geräusche.
Methodological aspects of clinical trials in tinnitus: a proposal for an international standard
Abstract: Chronic tinnitus is a common condition with a high burden of disease. While many different treatments are used in clinical practice, the evidence for the efficacy of these treatments is low and the variance of treatment response between individuals is high. This is most likely due to the great heterogeneity of tinnitus with respect to clinical features as well as underlying pathophysiological mechanisms. There is a clear need to find effective treatment options in tinnitus, however, clinical trials differ substantially with respect to methodological quality and design. Consequently, the conclusions that can be derived from these studies are limited and jeopardize comparison betwee…
Antipsychotic drugs antagonize human serotonin type 3 receptor currents in a noncompetitive manner
The serotonin type 3 (5-HT(3)) receptor is the only ligand-gated ion channel receptor for serotonin (5-HT). 5-HT(3) receptors play an important role in modulating the inhibitory action of dopamine in mesocorticolimbic brain regions. Neuroleptic drugs are commonly thought to exert their psychopharmacological action mainly through dopamine and serotonin type 2 (5-HT(2)) receptors. Except for clozapine, a direct pharmacological interaction of neuroleptics with 5-HT(3) receptors has not yet been described. Using the concentration-clamp technique, we investigated the effects of flupentixol, various phenothiazines, haloperidol, clozapine and risperidone on Na(+)-inward currents through 5-HT(3) re…