0000000000306953

AUTHOR

Laura López-mascaraque

showing 3 related works from this author

Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming

2021

Region-specific gene expression shared with neurons imparts to astrocytes competence for region-specific neuronal reprogramming.

EpigenomicsCellThalamusNeocortexBiology03 medical and health sciences0302 clinical medicineThalamusGene expressionmedicineEpigeneticsProgenitor cellNeural cellResearch Articles030304 developmental biologyNeurons0303 health sciencesMultidisciplinaryNeocortexSciAdv r-articlesmedicine.anatomical_structurenervous systemAstrocytesNeuroscienceReprogramming030217 neurology & neurosurgeryResearch ArticleNeuroscience
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Hypothalamus-olfactory system crosstalk: orexin a immunostaining in mice

2012

It is well known that olfaction influences food intake, and conversely, that an individual’s nutritional status modulates olfactory sensitivity. However, what is still poorly understood is the neuronal correlate of this relationship, as well as the connections between the olfactory bulb and the hypothalamus. The goal of this report is to analyze the relationship between the olfactory bulb and hypothalamus, focusing on orexin A immunostaining, a hypothalamic neuropeptide that is thought to play a role in states of sleep/wakefulness. Interestingly, orexin A has also been described as a food intake stimulator. Such an effect may be due in part to the stimulation of the olfactory bulbar pathway…

Olfactory systemmedicine.medical_specialtyLateral hypothalamus[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionNeuroscience (miscellaneous)Olfactionolfactory systemBiology03 medical and health sciencesCellular and Molecular NeuroscienceOrexin-A0302 clinical medicineInternal medicinemental disordersmedicineFood and Nutritionhypothalamus030304 developmental biologyOriginal Research0303 health sciencesimmunocytologyOlfactory tubercledigestive oral and skin physiologyimmunohistologyaobfood intake behaviourOrexinOlfactory bulbaob;food intake behaviour;hypothalamus;immunohistology;mob;olfactory system;orexin aEndocrinologymobnervous systemAlimentation et NutritionWakefulnessorexin aAnatomyfood intake behaviorNeuroscience[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgerypsychological phenomena and processeshormones hormone substitutes and hormone antagonistsNeuroscience
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Synaptogenesis in the mouse olfactory bulb during glomerulus development

2008

Synaptogenesis is essential for the development of neuronal networks in the brain. In the olfactory bulb (OB) glomeruli, numerous synapses must form between sensory olfactory neurons and the dendrites of mitral/tufted and periglomerular cells. Glomeruli develop from E13 to E16 in the mouse, coincident with an increment of the neuropil in the border between the external plexiform (EPL) and olfactory nerve layers (ONL), coupled to an extensive labelling of phalloidin and GAP-43 from the ONL to EPL. We have tracked synaptogenesis in the OB during this period by electron microscopy (EM) and immunolabelling of the transmembrane synaptic vesicle glycoprotein SV-2. No SV-2 labelling or synapses we…

Olfactory systemNeuropilTime FactorsPhalloidineSynaptic MembranesSynaptogenesisGAP-43Nerve Tissue ProteinsBiologymitral cellsSynaptic TransmissionOlfactory Receptor NeuronsMiceGAP-43 ProteinOlfactory MucosaOlfactory nerveolfactory sensory neuronsNeuropilmedicineAnimalsGlomerulus (olfaction)Membrane GlycoproteinsGeneral NeuroscienceSV-2Cell DifferentiationDendritesOlfactory BulbOlfactory bulbmedicine.anatomical_structureSynapsesembryonic structuresSynaptic VesiclesOlfactory ensheathing gliaolfactory epitheliumsense organsNeuroscienceOlfactory epitheliumBiomarkers
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