0000000000309021

AUTHOR

Jan ŠVancara

showing 4 related works from this author

LATE-BREAKING ABSTRACT: Phenotypes of COPD in central and Eastern Europe - The POPE study

2015

Introduction: Chronic obstructive pulmonary disease (COPD) represents a major health problem in Central and Eastern European (CEE) countries. However, data regarding symptom load and clinical phenotypes of patients with COPD in CEE remain largely unknown. Methods: Participation in the POPE Study (a multicentre, observational cross-sectional survey) was offered to consecutive outpatients with stable COPD in 11 CEE countries if they fulfilled the following criteria: age ≥ 40 years, smoking history ≥ 10 pack-years, post-bronchodilator (BD) FEV 1 /FVC Results: 3504 patients (66 ± 8.7 yrs, 69% male, post-BD FEV 1 53.0 ± 17.5% predicted, Charlson comorbidity index 2.0 ± 1.4, and 1.2 ± 1.6 exacerb…

Pediatricsmedicine.medical_specialtyCOPDeducation.field_of_studyChronic bronchitisbusiness.industryPopulationOverlap syndromemedicine.diseaserespiratory tract diseases3. Good healthEastern europeanFEV1/FVC ratioCharlson comorbidity indexmedicineObservational studybusinesseducation1.1 Clinical Problems
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CAT in COPD phenotypes (POPE study)

2016

Background: The COPD assessment test (CAT) is widely used for basic symptom evaluation in patients with COPD. The impact of COPD phenotypes on symptom scores using the CAT, however, remains largely unknown. Methods: The POPE-Study (NCT02119494) is an international, multicentre, observational cross-sectional survey of consecutive patients with COPD in Central and Eastern Europe (CEE). Respiratory symptoms using the modified Medical Research Council (mMRC) dyspnoea scale, and the CAT were recorded. Inclusion criteria: age ≥ 40 years, smoking history ≥ 10 pack-years, post-bronchodilator (BD) FEV1/FVC Results: 3366 COPD subjects (66 ± 8.8 yrs, post-BD FEV1 52.8 ± 18.5 % predicted, CAT 17.4 ± 7.…

Pediatricsmedicine.medical_specialtyCOPDChronic bronchitisbusiness.industryOverlap syndromemedicine.diseaseSmoking historyrespiratory tract diseases3. Good healthFEV1/FVC ratioInternal medicinemedicineCopd assessment testIn patient10. No inequalitybusiness5.2 Monitoring Airway Disease
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Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study.

2017

Chronic obstructive pulmonary disease (COPD) represents a major health problem in Central and Eastern European (CEE) countries; however, there are no data regarding clinical phenotypes of these patients in this region.Participation in the Phenotypes of COPD in Central and Eastern Europe (POPE) study was offered to stable patients with COPD in a real-life setting. The primary aim of this study was to assess the prevalence of phenotypes according to predefined criteria. Secondary aims included analysis of differences in symptom load, comorbidities and pharmacological treatment.3362 patients with COPD were recruited in 10 CEE countries. 63% of the population were nonexacerbators, 20.4% frequen…

Pulmonary and Respiratory MedicineMalePediatricsmedicine.medical_specialtyChronic bronchitisCross-sectional studyInternational CooperationPopulationVital CapacityComorbidity03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineForced Expiratory VolumemedicinePrevalenceHumans030212 general & internal medicineeducationBronchitisAgededucation.field_of_studyCOPDbusiness.industryData CollectionSmokingTobacco Use DisorderMiddle Agedmedicine.diseaseComorbidityrespiratory tract diseases3. Good healthEastern europeanBronchitis ChronicEuropeCross-Sectional StudiesPhenotypeTreatment Outcome030228 respiratory systemCohortBronchitisFemalebusinessThe European respiratory journal
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Pharmacotherapy of COPD in Central and Eastern Europe - The POPE study

2016

Introduction: In Central and Eastern Europe (CEE) the burden of chronic obstructive pulmonary disease (COPD) is high. It remains unknown whether patients are treated in line with GOLD recommendations or according to their phenotypes. Our aim was to analyze the treatment patterns of COPD in CEE. Methods: In the frame of the POPE study (ClinicalTrials.gov - NCT02119494) data including pharmacotherapy were collected in patients with stable COPD across 11 CEE countries. Results: 3366 patients (66±9 yrs, 70% male, FEV 1 53±18%) participated in the study. In all GOLD categories, the most widely used medications were long-acting beta-2 agonists (LABA), followed by long-acting antimuscarinic agents…

medicine.medical_specialtyCOPDbiologyExacerbationbusiness.industryPulmonary diseaseInhaled corticosteroidsOverlap syndromeLamabiology.organism_classificationmedicine.disease3. Good health03 medical and health sciences0302 clinical medicinePharmacotherapy030228 respiratory systemInternal medicinePhysical therapyMedicineIn patient030212 general & internal medicinebusinesshormones hormone substitutes and hormone antagonists1.12 Clinical Problems - COPD
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