6533b7dbfe1ef96bd126fde3
RESEARCH PRODUCT
CAT in COPD phenotypes (POPE study)
Ruzena TkacovaAlvis KramsAttila SomfayJurij SorliVladimir KoblizekKosta KostovKirill ZykovJan ŠVancaraAdam BarczykArschang ValipourMarc MiravitllesZuzana ZbozinkovaNeven TudorićBranislava Milenkovicsubject
Pediatricsmedicine.medical_specialtyCOPDChronic bronchitisbusiness.industryOverlap syndromemedicine.diseaseSmoking historyrespiratory tract diseases3. Good healthFEV1/FVC ratioInternal medicinemedicineCopd assessment testIn patient10. No inequalitybusinessdescription
Background: The COPD assessment test (CAT) is widely used for basic symptom evaluation in patients with COPD. The impact of COPD phenotypes on symptom scores using the CAT, however, remains largely unknown. Methods: The POPE-Study (NCT02119494) is an international, multicentre, observational cross-sectional survey of consecutive patients with COPD in Central and Eastern Europe (CEE). Respiratory symptoms using the modified Medical Research Council (mMRC) dyspnoea scale, and the CAT were recorded. Inclusion criteria: age ≥ 40 years, smoking history ≥ 10 pack-years, post-bronchodilator (BD) FEV1/FVC Results: 3366 COPD subjects (66 ± 8.8 yrs, post-BD FEV1 52.8 ± 18.5 % predicted, CAT 17.4 ± 7.8) were recruited. On the whole 63.3 % were non-exacerbators (NON-AE), 20.4 % frequent exacerbators with chronic bronchitis (AE CB), 9.5 % frequent exacerbators without CB (AE NON-CB), and 6.9 % were patients with asthma-COPD overlap syndrome (ACOS). There were apparent statistically significant differences ( Conclusion: There were noted significant differences in total CAT and individual CAT items between clinical phenotypes of COPD.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-09-01 | 5.2 Monitoring Airway Disease |