showing 7 related works from this author
Occupational factors and risk of adult bone sarcomas:a multicentric case-control study in Europe
2006
International audience; We investigated the association between occupational factors and risk of bone sarcoma, a rare tumor with a largely unknown aetiology. A multicentric case-control study was conducted in 7 European countries in 1995-97. Ninety-six cases aged 35-69 years with a centrally reviewed diagnosis of bone sarcoma (68 chondrosarcomas and 28 osteosarcomas) were compared to 2,632 population (68%) or colon cancer (32%) controls. Subjects were interviewed to obtain information on occupational, medical and reproductive history, smoking and alcohol consumption and selected exposures including use of pesticides. Response proportions were 90% among cases and 66% among controls. Odds rat…
Validación de un cuestionario para medir retrospectivamente la exposición laboral a plaguicidas
1997
ResumenObjetivosValidar un cuestionario diseñado para medir retrospectivamente la exposición laboral a plaguicidas en un estudio de casos y controles sobre trabajadores expuestos a plaguicidas y malformaciones congénitas.MétodosSe compara la información obtenida mediante una entrevista personal con 56 agricultores con: 1) una entrevista con los empleadores de los agricultores, 2) la observación directa de los lugares de trabajo y 3) un cuestionario que cumplimentaron los agncultores durante la realización del Programa de Capacitación para Manipuladores de Plaguicidas.ResultadosLos índices de exactitud y fiabilidad fueron altos para las variables «cultivos trabajados», «períodos de tratamien…
Review: Evolution of evidence on PFOA and health following the assessments of the C8 Science Panel.
2020
Abstract Background The C8 Science Panel was composed of three epidemiologists charged with studying the possible health effects of PFOA in a highly exposed population in the mid-Ohio Valley. The Panel determined in 2012 there was a ‘probable link’ (i.e., more probable than not based on the weight of the available scientific evidence) between PFOA and high cholesterol, thyroid disease, kidney and testicular cancer, pregnancy-induced hypertension, and ulcerative colitis. Objective Here, former C8 Science Panel members and collaborators comment on the PFOA literature regarding thyroid disorders, cancer, immune and auto-immune disorders, liver disease, hypercholesterolemia, reproductive outcom…
Perfluoroalkyl substances and immune cell counts in adults from the Mid-Ohio Valley (USA)
2021
Highlights • The literature on PFASs and circulating levels of immune cells is scarce. • Study of the association between PFASs and white blood cells at two different time points. • Cross-sectional study on the association between PFASs and lymphocyte subsets. • Positive association between PFHxS and total lymphocytes, especially for cell count. • Positive, but less consistent, association between PFOA and PFOS and total lymphocytes.
Maternal occupation in the leather industry and selected congenital malformations.
1998
OBJECTIVES: Data from a hospital based case-control study were analysed to assess the relation between maternal occupation in the leather industry and several groups of congenital defects (nervous system, cardiac defects of closure, oral cleft, epispadia or hypospadia, and multiple anomalies). METHODS: Cases and controls were selected from eight public hospitals in Comunidad Valenciana, Spain, in 1993 and 1994. Cases were located from the hospital discharge records, including children born and diagnosed in some of the selected hospitals during their first year of life. Controls were selected from births without congenital defects in the same hospitals and dates of the cases (ratio 1:1). Bot…
Exposure to perfluoroalkyl substances and thyroid function in pregnant women and children: A systematic review of epidemiologic studies
2017
Introduction: Thyroid hormones (THs) are especially important for brain maturation and development during the fetal period and childhood. Several epidemiological studies have assessed the possible association between exposure to perfluoroalkyl substances (PFAS) and thyroid outcomes during the early stages of life. We aimed to review this evidence. Methods: We conducted a systematic review in compliance with the PRISMA Statement (search conducted in PubMed and Embase, as well as in the citations of the selected articles). We chose studies if they dealt with thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxin (T4), or thyroid dysfunctions, and perfluorohexane sulfonate (PFHxS),…
Risk factors for extrahepatic biliary tract carcinoma in men: medical conditions and lifestyle: results from a European multicentre case-control stud…
2007
OBJECTIVES: To identify risk factors of carcinoma of the extrahepatic biliary tract in men. METHODS: Newly diagnosed and histologically confirmed patients, 35-70 years old, were interviewed between 1995 and 1997 in Denmark, Sweden, France, Germany and Italy. Population controls were frequency-matched by age and region. Adjusted odds ratios and 95%-confidence intervals were estimated by logistic regression. RESULTS: The analysis included 153 patients and 1421 controls. The participation proportion was 71% for patients and 61% for controls. Gallstone disease was corroborated as a risk factor for extrahepatic biliary tract carcinoma in men (odds ratio 2.49; 95% confidence interval 1.32-4.70), …