6533b82bfe1ef96bd128d747

RESEARCH PRODUCT

Perfluoroalkyl substances and immune cell counts in adults from the Mid-Ohio Valley (USA)

Joseph B. MargolickGiovanni LeonardiMichael I. LusterOlga CostaChristian CarrizosaTony FletcherMaria-josé Lopez-espinosa

subject

AdultSerum010504 meteorology & atmospheric sciencesWater contaminationCellPhysiologyCell Count010501 environmental sciencesBiology01 natural sciencesArticlePerfluorononanoic acidchemistry.chemical_compoundImmune systemPFASsInterquartile rangeWhite blood cellmedicineHumansGE1-350LymphocytesOhio0105 earth and related environmental sciencesGeneral Environmental ScienceFluorocarbonsEnvironmental sciencesPerfluorooctaneImmune systemmedicine.anatomical_structureAlkanesulfonic AcidschemistryWhite blood cellsPerfluorooctanoic acidEnvironmental PollutantsCaprylates

description

Highlights • The literature on PFASs and circulating levels of immune cells is scarce. • Study of the association between PFASs and white blood cells at two different time points. • Cross-sectional study on the association between PFASs and lymphocyte subsets. • Positive association between PFHxS and total lymphocytes, especially for cell count. • Positive, but less consistent, association between PFOA and PFOS and total lymphocytes.

https://doi.org/10.1016/j.envint.2021.106599