0000000000323207
AUTHOR
H.j. Schmitt
Respiratorisches-Syncytial-Virus
Die Arbeitsgemeinschaft Influenza (AGI) erfasst seit 1992 in den Winterhalbjahren das Auftreten von akuten respiratorischen Erkrankungen (ARE) mit einem Netzwerk aus primarversorgenden Praxen. Zusatzlich werden in einem Teil der Praxen stichprobenartig Abstriche entnommen und in dem Nationalen Referenzzentrum fur Influenza und anderen Labors auf Influenzaviren untersucht. Im Winter 1998/99 wurde in einem Netzwerk aus 550 Arztpraxen bundesweit eine Erhohung der Morbiditat akuter Atemwegserkrankungen beobachtet, die nicht durch Influenza verursacht wurde. Um die Ursache zu ergrunden, wurden weitere verfugbare Daten wie die Beobachtungen des Laborberichtssystems fur respiratorische Erkrankunge…
Serial measurements of transient evoked otoacoustic emissions (TEOAEs) in healthy newborns and in newborns with perinatal infection.
Detection of hearing impairment in early childhood is difficult. We serially recorded transient evoked otoacoustic emissions (TEOAEs) to search for signs of ototoxicity in term, healthy newborns and compared the results to a second group of term babies treated for perinatally acquired bacterial infection with ampicillin plus either cefotaxime or plus aminoglycoside. At initial evaluation, in the group of 45 healthy children born at term, well reproducible emissions were observed in all but two children. In each of these two, initially well reproducible TEOAEs were detected in one ear only. At the time of the second recording (mean at day 8.5) excellent emissions were seen in all ears of all…
Evoked otoacoustic emissions and pure tone threshold audiometry in patients receiving cisplatinum therapy.
Eight children and young adults with cancer were evaluated serially using pure tone audiometry as well as registration of click-evoked otoacoustic emissions (EOAE) 1 day prior to therapy as well as after various numbers of doses of cisplatinum. A reduction of EOAE-amplitudes following cisplatinum therapy was observed in all patients. This reduction tended to recover after the end of cisplatinum administration. Since EOAE are believed to result from cochlear bio-mechanical processes, the reduced emissions are interpreted as signs of cochlear dysfunction. We conclude, that EOAE testing may be a simple, non-invasive method that may detect early, transient functional impairment of hearing due t…