0000000000330196

AUTHOR

Dennis Fiorini

0000-0001-5055-6099

showing 4 related works from this author

Fixed oil from seeds of narrow-leaved ash (F. angustifolia subsp. angustifolia): Chemical profile, antioxidant and antiproliferative activities.

2019

Fraxinus angustifolia subsp. angustifolia is a plant with an age-old use for the production of manna. However, it is also a valuable source of fixed oil rich-seeds. In the present study we examined the chemical and biological properties of this oil in order to support a possible application in foodstuffs, nutraceuticals and cosmetics. Fatty acid composition, volatile and phenolic substances were evaluated. Oleic and linoleic acid represented 45.5% and 50.0%, respectively, of the total fatty acid composition. Among polar phenolic substances identified (secoiridoids, phenylethanoid glycosides, phenolic acids and alcohols, flavonoids, coumarins) isoverbascoside is for the first time reported i…

PolyphenolAntioxidant030309 nutrition & dieteticsLinoleic acidmedicine.medical_treatmentFixed oilAntiproliferative activityFraxinus angustifoliaAntioxidantsSettore BIO/01 - Botanica Generale03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyNutraceuticalAntioxidant activityGlucosidesPhenolsBiological propertymedicineHydroxybenzoatesOils VolatilePlant OilsSettore BIO/15 - Biologia FarmaceuticaFood scienceFraxinus angustifolia subsp. angustifoliachemistry.chemical_classificationFlavonoids0303 health sciencesABTSbiologyPlant ExtractsSettore BIO/02 - Botanica SistematicaFatty AcidsGlycosideMelanoma AmelanoticSettore CHIM/06 - Chimica Organica04 agricultural and veterinary sciencesPhenylethanoidFatty acidbiology.organism_classification040401 food sciencechemistrySeedsVolatile substancesFood ScienceOleic AcidFood research international (Ottawa, Ont.)
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The Nonvolatile and Volatile Metabolites of Prangos ferulacea and Their Biological Properties

2019

Abstract Prangos ferulacea (L.) Lindl. (Fam. Apiaceae), an orophilous species of eastern Mediterranean and western Asia, possesses a number of biological properties that are worthy of exploitation in different fields. Phytochemical investigations revealed the presence of coumarins, prenyl-coumarins, and furano-coumarins as the main constituents of this species, as well as several flavonoids. Among prenyl-coumarins, osthol is a promising apoptotic agent quite selective toward cancer cells. In addition, the essential oils have been extensively investigated, and several chemotypes have been identified. This work reviews the literature on this species published between 1965 and 2018, describes …

Anti-Infective AgentPrangos ferulaceaPharmaceutical Science01 natural sciencesAntioxidantsAnalytical Chemistrylaw.inventionchemistry.chemical_compoundAnti-Infective AgentslawDrug Discoveryheterocyclic compoundsAnalgesicsbiologyTraditional medicinePhytochemicalprenyl-coumarinsMolecular MedicineAntioxidantfurano-coumarinOstholHumanCoumarinessential oilBiological propertyAnimalsHumansHypoglycemic AgentsVolatile metabolitesEssential oilPharmacologyPrangos ferulaceacoumarinsApiaceaeHypoglycemic AgentChemotypeAnimalPlant Extracts010405 organic chemistryOrganic ChemistryPrangos ferulacea; Apiaceae; coumarins; prenyl-coumarins; furano-coumarinsSettore CHIM/06 - Chimica Organicabiology.organism_classification0104 chemical sciencesprenyl-coumarin010404 medicinal & biomolecular chemistryComplementary and alternative medicinechemistrySettore BIO/03 - Botanica Ambientale E ApplicataAnalgesicApiaceaefurano-coumarinsPlanta Medica
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Composition and biological activities of the essential oil from a Sicilian accession of Prangos ferulacea (L.) Lindl

2019

Prangos ferulacea (L.) Lindl. (Fam. Apiaceae), is an orophilous species of eastern Mediterranean and western Asia which possesses several biological properties, which are worthy of exploitation in different fields. With the aim to provide new insights into the phytochemistry and pharmacology of this species, a local accession growing in Sicily (South Italy) was investigated as well. Notably, the P. ferulacea essential oil chemical composition and the antioxidant, anti-acetylcholinesterase (AChE) and cytotoxic activities have been studied. This analysis allowed to identify a new chemotype and to report good biological results for this oil. © 2019 Informa UK Limited, trading as Taylor & F…

biological activitiePrangos ferulaceaPlant ScienceBiology01 natural sciencesBiochemistryAccessionessential oilAnalytical Chemistrylaw.inventionlawBiological propertyBotanyEssential oilPrangos ferulaceaApiaceae010405 organic chemistryOrganic ChemistryWestern asiabiology.organism_classificationlanguage.human_language0104 chemical sciences010404 medicinal & biomolecular chemistrylanguageComposition (visual arts)SicilianApiaceae
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Kundmannia sicula (L.) DC: a rich source of germacrene D

2017

AbstractObjective: Kundmannia sicula is an herbaceous plant belonging to the family Apiaceae and is distributed in the Mediterranean coastal areas where it occurs in arid places. In this work, we have analysed the essential oil distilled from the aerial parts of K. sicula from Sicily (Italy) and its biological activity. Methods: GC-MS was used to analyze the chemical composition, whereas its antioxidant capacity and cytotoxicity on three human tumour cells (A375, MDA MB-231 and HCT 116) were evaluated by DPPH, ABTS, FRAP and MTT methods, respectively. Result: The essential oil resulted very rich of the sesquiterpene hydrocarbon germacrene D (81.2%). Moreover, the K. sicula oil displayed rel…

AntioxidantantioxidantDPPHmedicine.medical_treatmentBiologySesquiterpene01 natural sciencesessential oillaw.inventionchemistry.chemical_compoundlawKundmannia siculaBotanygermacrene DmedicineKundmannia siculaEssential oilABTS010405 organic chemistryChemistry (all)Biological activityGeneral ChemistryHerbaceous plant0104 chemical sciences010404 medicinal & biomolecular chemistrychemistrycytotoxicity
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