The Nonvolatile and Volatile Metabolites of Prangos ferulacea and Their Biological Properties

6533b82bfe1ef96bd128e157

RESEARCH PRODUCT

The Nonvolatile and Volatile Metabolites of Prangos ferulacea and Their Biological Properties

Filippo Maggi Vincenzo Ilardi Luana Quassinti Alessandro Venditti Massimo Bramucci Giulio Lupidi Maurizio Bruno Dennis Fiorini

subject

Anti-Infective Agent Prangos ferulacea Pharmaceutical Science 01 natural sciences Antioxidants Analytical Chemistry law.invention chemistry.chemical_compound Anti-Infective Agents law Drug Discovery heterocyclic compounds Analgesics biology Traditional medicine Phytochemical prenyl-coumarins Molecular Medicine Antioxidant furano-coumarin Osthol Human Coumarin essential oil Biological property Animals Humans Hypoglycemic Agents Volatile metabolites Essential oil Pharmacology Prangos ferulacea coumarins Apiaceae Hypoglycemic Agent Chemotype Animal Plant Extracts 010405 organic chemistry Organic Chemistry Prangos ferulacea; Apiaceae; coumarins; prenyl-coumarins; furano-coumarins Settore CHIM/06 - Chimica Organica biology.organism_classification 0104 chemical sciences prenyl-coumarin 010404 medicinal & biomolecular chemistry Complementary and alternative medicine chemistry Settore BIO/03 - Botanica Ambientale E Applicata Analgesic Apiaceae furano-coumarins

description

Abstract Prangos ferulacea (L.) Lindl. (Fam. Apiaceae), an orophilous species of eastern Mediterranean and western Asia, possesses a number of biological properties that are worthy of exploitation in different fields. Phytochemical investigations revealed the presence of coumarins, prenyl-coumarins, and furano-coumarins as the main constituents of this species, as well as several flavonoids. Among prenyl-coumarins, osthol is a promising apoptotic agent quite selective toward cancer cells. In addition, the essential oils have been extensively investigated, and several chemotypes have been identified. This work reviews the literature on this species published between 1965 and 2018, describes its volatile and nonvolatile metabolites, and outlines its pharmacological effects.

year	journal	country	edition	language
2019-01-01	Planta Medica

https://doi.org/10.1055/a-0873-8622

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