0000000000331195

AUTHOR

Clàudia Coll

showing 3 related works from this author

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metab…

2021

Gut: first published.

Male0301 basic medicine2312MicrobiologiaGut floraTranscriptomeMice0302 clinical medicineOverweight persons1506Gut MicrobiotaPrefrontal cortexhealth care economics and organizationsdigestive oral and skin physiologyGastroenterologyIntestins -- MalaltiesFecal Microbiota TransplantationMiddle AgedPersones obesesserotonin3. Good healthInhibition PsychologicalIntestins -- MicrobiologiaPhenotypemedicine.anatomical_structureintestinal microbiology ; microbiota ; obesity.ObesitatFemaleIntestines -- DiseasesdopamineperformanceAdultmedicine.medical_specialtytryptophan depletionPhysical exerciseBiologyIntestines -- Microbiologydigestive systemMicrobiologyAmino Acids Aromatic03 medical and health sciencesMetabolomicsInternal medicinemedicineAnimalsHumansObesityAnterior cingulate cortexAgedIntestinal microbiologyMetabolismbiology.organism_classificationCarbonGastrointestinal MicrobiomeFatty LiverCross-Sectional Studies030104 developmental biologyEndocrinologyTranscriptome030217 neurology & neurosurgeryStroop effect
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Presence of Blastocystis in gut microbiota is associated with cognitive traits and decreased executive function.

2022

Growing evidence implicates the gut microbiome in cognition. Blastocystis is a common gut single-cell eukaryote parasite frequently detected in humans but its potential involvement in human pathophysiology has been poorly characterized. Here we describe how the presence of Blastocystis in the gut microbiome was associated with deficits in executive function and altered gut bacterial composition in a discovery (n = 114) and replication cohorts (n = 942). We also found that Blastocystis was linked to bacterial functions related to aromatic amino acids metabolism and folate-mediated pyrimidine and one-carbon metabolism. Blastocystis-associated shifts in bacterial functionality translated into …

Intestins--MicrobiologiaMicrobiologiaPathogenesisBlastocystis InfectionsMicrobiologyMETAGENOMICSMEMBERExecutive FunctionMicegut microbiota ; Blastocystis ; executive function ; gut microbiome-brain axis.CognitionAparell digestiuDiagnosisAnimalsHumansEcology Evolution Behavior and SystematicsBlastocistMEMORYDNAGastrointestinal MicrobiomeCognicióBlastocystisBlastocist -- InfeccióMicrobiomaBiomarkersThe ISME journal
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Obesity status and obesity-associated gut dysbiosis effects on hypothalamic structural covariance

2021

[Background]: Functional connectivity alterations in the lateral and medial hypothalamic networks have been associated with the development and maintenance of obesity, but the possible impact on the structural properties of these networks remains largely unexplored. Also, obesity-related gut dysbiosis may delineate specific hypothalamic alterations within obese conditions. We aim to assess the effects of obesity, and obesity and gut-dysbiosis on the structural covariance differences in hypothalamic networks, executive functioning, and depressive symptoms.

AdultMalemedicine.medical_specialtyDisbiosisEndocrinology Diabetes and MetabolismHypothalamusMedicine (miscellaneous)StriatumIntestines -- MicrobiologyArticleBody Mass IndexGlàndules endocrinesInternal medicineNeural PathwaysmedicineHumansObesityEndocrine glandsNutrition and DieteticsHipotàlembusiness.industryFunctional connectivityMiddle Agedmedicine.diseaseObesityIntestins -- MicrobiologiaCross-Sectional StudiesEndocrinologyHypothalamusStructural covarianceObesitatDysbiosisFemaleGut dysbiosisbusinessInsulaHypothalamic DiseasesExecutive dysfunction
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