0000000000338048

AUTHOR

Sarah Fleming

0000-0002-7655-4806

showing 4 related works from this author

The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones: Analyses From the INTERPHONE Study

2016

When investigating the association between brain tumors and use of mobile telephones, accurate data on tumor position are essential, due to the highly localized absorption of energy in the human brain from the radio-frequency fields emitted. We used a point process model to investigate this association using information that included tumor localization data from the INTERPHONE Study (Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the United Kingdom). Our main analysis included 792 regular mobile phone users diagnosed with a glioma between 2000 and 2004. Similar to earlier results, we found a statistically significant association …

AdultMalemedicine.medical_specialtyTELEPHONENeoplasms Radiation-InducedTime FactorsEpidemiologyOriginal ContributionsTumor burdenBrain tumorAudiologyMOBILE TELEPHONES03 medical and health sciences0302 clinical medicinePhoneRisk FactorsRecall biasEXPOSITION AU RISQUECERVEAUMedicineHumans030212 general & internal medicineEpidemiologic researchSelf reportONDERADIO-FREQUENCY ELECTROMAGNETIC FIELDSbusiness.industryBrain NeoplasmsINTERPHONE STUDYMiddle Agedmedicine.diseaseTumor BurdenMobile phone030220 oncology & carcinogenesisEpidemiologic Research DesignGLIOMAFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieSPATIAL POINT PATTERNNeoplasm GradingbusinessINTRACRANIAL DISTRIBUTIONCell PhoneTUMEUR
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Diagnostic radiological examinations and risk of intracranial tumours in adults—findings from the Interphone Study

2021

Abstract Background Exposure to high doses of ionizing radiation is among the few well-established brain tumour risk factors. We used data from the Interphone study to evaluate the effects of exposure to low-dose radiation from diagnostic radiological examinations on glioma, meningioma and acoustic neuroma risk. Methods Brain tumour cases (2644 gliomas, 2236 meningiomas, 1083 neuromas) diagnosed in 2000–02 were identified through hospitals in 13 countries, and 6068 controls (population-based controls in most centres) were included in the analysis. Participation across all centres was 64% for glioma cases, 78% for meningioma cases, 82% for acoustic neuroma cases and 53% for controls. Informa…

Adultmedicine.medical_specialtyionizingEpidemiologyPopulationAcoustic neuromameningiomaacousticMeningioma03 medical and health sciences0302 clinical medicineIsotopesRisk FactorsgliomaGliomaMeningeal Neoplasmsotorhinolaryngologic diseasesHumansMedicineeducationeducation.field_of_studyRadiationmedicine.diagnostic_testBrain Neoplasmsbusiness.industryNeuroma AcousticGeneral MedicineOdds ratiomedicine.diseaseNeuromastudies3. Good health3141 Health care scienceCase-Control Studies030220 oncology & carcinogenesisneuromaRadiologybusinessCell Phonecase-control030217 neurology & neurosurgeryCerebral angiographyComputed tomography of the headInternational Journal of Epidemiology
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0329 Occupational exposure to metals and welding fumes, and risk of glioma in the interocc study

2017

Background Brain tumouraetiology is poorly understood. Based on their ability to pass through the blood-brain barrier, it has been hypothesised that exposure to metals may increase the risk of brain cancer. Results from the few epidemiological studies on this issue are inconsistent. Methods We investigated the relationship between glioma risk and occupational exposure to five metals - lead, cadmium, nickel, chromium and iron- as well as to welding fumes, using data from the seven-country INTEROCC study. A total of 1800 incident glioma cases and 5160 controls aged 30–69 years were included in the analysis. Lifetime occupational exposure to the agents was assessed using the INTEROCC JEM, a mo…

medicine.medical_specialtyCadmiumbusiness.industryJob-exposure matrixchemistry.chemical_elementCumulative ExposureOdds ratioLogistic regressionmedicine.diseaseConfidence intervalchemistryEnvironmental healthGliomaEpidemiologymedicinebusinessOral Presentation
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Occupational solvent exposure and risk of glioma in the INTEROCC study

2017

BACKGROUND: The aetiology of glioma remains largely unknown. Occupational solvent exposure has been suggested as a putative cause of glioma, but past studies have been inconsistent. We examined the association between a range of solvents and glioma risk within the INTEROCC project, a study of brain tumours and occupational exposures based on data from seven national case-control studies conducted in the framework of the INTERPHONE study. We also investigated associations according to tumour grade.METHODS: Data from the seven countries were standardised and then combined into one aggregate data set. Pooled odds ratios (ORs) were estimated for adjusted models that included sex, age, country-r…

MaleOncologyMESH: United KingdomCancer ResearchEpidemiology[SDV]Life Sciences [q-bio]MESH: Neoplasm GradingMESH: SolventsMESH: Occupational ExposureMESH: GliomaTumor gradechemistry.chemical_compound0302 clinical medicineRisk FactorsMESH: New ZealandMESH: Risk FactorsGermanyOdds RatioIsraelYoung adultMESH: AgedOccupationMESH: Middle AgedBrain NeoplasmsAge FactorsMESH: IsraelGliomaMiddle Aged030210 environmental & occupational healthMESH: Case-Control Studies3. Good healthOncologyMESH: Young Adult030220 oncology & carcinogenesisSolventMESH: Brain NeoplasmsFemaleFranceAdultCanadamedicine.medical_specialtyAdolescentCase–control studyJob-exposure matrixMESH: AustraliaYoung Adult03 medical and health sciencesSex FactorsMESH: Sex FactorsMESH: CanadaOccupational ExposureInternal medicineGliomamedicineJournal ArticleHumansMESH: GermanyAgedMESH: AdolescentMESH: Age FactorsMESH: Humansbusiness.industryAustraliaCase-control studyMESH: AdultOdds ratiomedicine.diseaseUnited KingdomConfidence intervalMESH: MaleMESH: Odds RatioMESH: FrancechemistryCase-Control StudiesSolventsNeoplasm GradingSolvent exposurebusinessMESH: FemaleNew Zealand
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