0000000000338901
AUTHOR
M. C. Caccami
Development and characterization of xyloglucan-poly(vinyl alcohol) hydrogel membrane for Wireless Smart wound dressings
Abstract Hydrogel-based smart wound dressings that combine the traditional favourable properties of hydrogels as skin care materials with sensing functions of relevant biological parameters for the remote monitoring of wound healing are under development. In particular, lightweight, ultra-high frequency radiofrequency identification (UHF RFID) sensor are adjoined to xyloglucan-poly(vinyl alcohol) hydrogel films to battery-less monitor moisture level of the bandage in contact with the skin, as well as wireless transmit the measured data to an off-body reader. This study investigates the swelling behavior of the hydrogels in contact with simulated biological fluids, and the modification of th…
Idrogeli a base di xyloglucano per la produzione di medicazioni avanzate nel trattamento delle ferite
In questo lavoro sono stati preparati film sottili di idrogelo (reticolati fisicamente o chimicamente) a base di xyloglucano (XG) e XG/polivinilalcol (PVA), a cui si è aggiunto glicerolo come plasticizzante. Lo xyloglucano è un polisaccaride di origine vegetale, caratterizzato da una catena principale di (1,4)--Dglucosio con ramificazioni laterali di (1-6)-α-xilosio, parzialmente sostituite con (1-2)–β galattosio. E’ stata indagata la possibilità di modulare la densità di reticolazione dell’idrogelo per ottenere il miglior compromesso tra resistenza meccanica e flessibilità, l’integrità strutturale nel tempo e la capacità di assorbire fluidi biologici o trattenere l’umidità. Inoltre, ne è …
Development and characterization of xyloglucan-poly(vinyl alcohol) hydrogel membrane for wireless smart wound dressings
Research which addresses advanced wound management can contribute to the needs of modern healthcare, especially in situations that require continuous monitoring, analysis, responsive therapeutic treatments and data recording. The development of “smart” bandages and dressings that can remotely monitor relevant parameters for the wound healing process without a hospital intervention can be very useful tools for patients and physicians and for advancing the understanding of the healing process. In the present work, biocompatible xyloglucan/poly(vinyl alcohol) hydrogels are being developed as smart wound dressings that, in addition to the traditional favorable properties of hydrogels as skin ca…