6533b7d9fe1ef96bd126c419
RESEARCH PRODUCT
Development and characterization of xyloglucan-poly(vinyl alcohol) hydrogel membrane for Wireless Smart wound dressings
Clelia DispenzaM. C. CaccamiMassimiliano ZingalesGaetano MarroccoDaniela GiacomazzaMaria Antonietta SabatinoSara AmendolaGioacchino AlottaCecilia OcchiuzziAlessia Ajovalasitsubject
PermittivityVinyl alcoholMaterials sciencePolymers and PlasticsGeneral Physics and Astronomy02 engineering and technologyDielectricPhysics and Astronomy (all)030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compound0302 clinical medicineHydrogels; Wound dressings; Dielectric properties; Swelling; RFID sensors; Epidermal electronicsMaterials ChemistrymedicineHydrogel membraneEpidermal electronicSwellingRFID sensorsPolymers and PlasticRFID sensorOrganic Chemistrytechnology industry and agricultureHydrogelsSettore ING-INF/02 - Campi Elettromagnetici021001 nanoscience & nanotechnologySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Characterization (materials science)Dielectric propertieXyloglucanHydrogelSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiWound dressingschemistryWound dressingDielectric propertiesSelf-healing hydrogelsSettore CHIM/07 - Fondamenti Chimici Delle TecnologieSwellingmedicine.symptomSettore ICAR/08 - Scienza Delle Costruzioni0210 nano-technologyBiomedical engineeringEpidermal electronicsdescription
Abstract Hydrogel-based smart wound dressings that combine the traditional favourable properties of hydrogels as skin care materials with sensing functions of relevant biological parameters for the remote monitoring of wound healing are under development. In particular, lightweight, ultra-high frequency radiofrequency identification (UHF RFID) sensor are adjoined to xyloglucan-poly(vinyl alcohol) hydrogel films to battery-less monitor moisture level of the bandage in contact with the skin, as well as wireless transmit the measured data to an off-body reader. This study investigates the swelling behavior of the hydrogels in contact with simulated biological fluids, and the modification of their morphology, mechanical properties, and dielectric properties in a wide range of frequencies (100–106 Hz and 108–1011 Hz). The films absorb simulated body fluids up to approximately four times their initial weight, without losing their integrity but undergoing significant microstructural changes. We observed relevant linear increases of electric conductivity and permittivity with the swelling degree, with an abrupt change of slope that is related to the network rearrangements occurring upon swelling.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-09-01 |