0000000000349221

AUTHOR

Jean-marcel Brun

showing 2 related works from this author

No change in apolipoprotein AI metabolism when subcutaneous insulin infusion is replaced by intraperitoneal insulin infusion in type 1 diabetic patie…

2006

In type 1 diabetic patients, the replacement of subcutaneous insulin infusion by intraperitoneal insulin infusion restores the normal physiological gradient between the portal vein and the peripheral circulation, which is likely to modify HDL metabolism. This stable isotope kinetic study was designed to compare HDL apolipoprotein (apo) AI metabolism in seven type 1 diabetic patients first treated by continuous subcutaneous insulin infusion by an external pump and then 3 months after the beginning of intraperitoneal insulin infusion by an implantable pump. Glycaemic control was comparable under subcutaneous and intraperitoneal insulin infusion (HbA1c=7.34+/-0.94% versus 7.24+/-1.00%, NS). HD…

AdultMalemedicine.medical_specialtyApolipoprotein Bmedicine.medical_treatmentCarbon Compounds InorganicSulfidesAdministration Cutaneouschemistry.chemical_compoundInsulin Infusion SystemsDiabetes mellitusInternal medicinemedicineHumansInsulinInfusions ParenteralPancreatic hormoneType 1 diabetesTriglyceridebiologyApolipoprotein A-Ibusiness.industryCholesterolInsulinMetabolismMiddle Agedmedicine.diseaseKineticsEndocrinologyDiabetes Mellitus Type 1chemistrybiology.proteinFemaleCardiology and Cardiovascular MedicinebusinessLipoproteins HDLAtherosclerosis
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Assessment of induced corneal hypoxia in diabetic patients

2002

Comparative Study Address correspondence and reprint requests to Dr. C. Creuzot-Garcher, Service d'Ophtalmologie, CHU, Hopital Général, 3 Rue du Faubourg Raines, BP 1519, 21033 Dijon, France. E-mail: Catherine.creuzot-garcher@chu-dijon.fr; To assess the control of corneal hydration in patients with diabetes during a contact lens-induced hypoxia. Corneal stress was induced in 15 patients with diabetes and 23 healthy patients by having them wear contact lenses for 2 hours. Pachymetries were measured and corneal parameters (percentage recovery per hour [PRPH], time for deswelling [T99%] and induced swelling [IS]) were calculated. In the mean time, tears were collected to assess the activity of…

AdultMalemedicine.medical_specialtyPathologyCell CountCorneachemistry.chemical_compoundStress PhysiologicalOphthalmologyLactate dehydrogenaseDiabetes mellitusHumansMedicineIn patient[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrgansHypoxiaAged[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyL-Lactate Dehydrogenasebusiness.industryCorneal EdemaEndothelium CornealMiddle AgedHypoxia (medical)Contact Lenses Hydrophilicmedicine.diseaseeye diseasesOphthalmologyDiabetes Mellitus Type 1Diabetes Mellitus Type 2chemistry[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory OrgansTearsTearsFemaleCorneal hypoxiasense organsmedicine.symptomSwellingbusinessAnaerobic exercise[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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