0000000000356750

AUTHOR

Oleg Balanovsky

showing 5 related works from this author

Ten millennia of hepatitis B virus evolution

2021

Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd…

Phylogeographic historyHepatitis B/history01 natural sciencesThe RepublicCommunicable Diseases EmergingGermanCommunicable Diseases Emerging/historyAgency (sociology)Science and technologyComputingMilieux_MISCELLANEOUSHistory AncientPhylogenymedia_common0303 health sciencesMultidisciplinaryAncient DNAEuropean researchvirus diseasesGenomicsHepatitis B3. Good healthEuropelanguageComputingMethodologies_DOCUMENTANDTEXTPROCESSINGChristian ministryPaleogenomic analysesAsian Continental Ancestry Group010506 paleontologyHepatitis B virusAsiaHepatitis B virus/classificationEuropean Continental Ancestry GroupLibrary scienceBiología CelularWhite PeopleMarie curieEvolution Molecular03 medical and health sciencesAmerican NativesAsian PeoplePolitical scienceGenomic datamedia_common.cataloged_instanceHumansSlovakEuropean unionAmerican Indian or Alaska Native030304 developmental biology0105 earth and related environmental sciencesGenetic VariationPaleontologyPrehistoriaA300language.human_languagedigestive system diseasesAmerican natives; Americas; Asia; Asian continental ancestry group; Communicable diseases Emerging; Europe; European continental ancestry group; Evolution molecular; Genetic variation; Genomics; Hepatitis B; Hepatitis B virus; History Ancient; Humans; Paleontology; PhylogenyAmericas
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Ancient DNA from European early neolithic farmers reveals their near eastern affinities.

2010

The first farmers from Central Europe reveal a genetic affinity to modern-day populations from the Near East and Anatolia, which suggests a significant demographic input from this area during the early Neolithic.

010506 paleontologyArchaeogeneticsQH301-705.5PopulationPopulation geneticsBiologyDNA Mitochondrial01 natural sciencesGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesDemic diffusionGenetics and Genomics/Population GeneticsHuman population geneticsHumansBiology (General)education030304 developmental biology0105 earth and related environmental sciences2. Zero hungerGeneticsEvolutionary Biology0303 health scienceseducation.field_of_studyGeneral Immunology and MicrobiologyFossilsGeneral NeurosciencePaleogeneticsAgricultureEmigration and ImmigrationEvolutionary Biology/Human EvolutionEuropeAncient DNAEvolutionary biologySynopsisGeneral Agricultural and Biological SciencesResearch ArticleHuman mitochondrial DNA haplogroupPLoS Biology
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The Genetic History of Northern Europe

2017

Recent ancient DNA studies have revealed that the genetic history of modern Europeans was shaped by a series of migration and admixture events between deeply diverged groups. While these events are well described in Central and Southern Europe, genetic evidence from Northern Europe surrounding the Baltic Sea is still sparse. Here we report genome-wide DNA data from 24 ancient North Europeans ranging from ~7,500 to 200 calBCE spanning the transition from a hunter-gatherer to an agricultural lifestyle, as well as the adoption of bronze metallurgy. We show that Scandinavia was settled after the retreat of the glacial ice sheets from a southern and a northern route, and that the first Scandinav…

0303 health sciencesgeographygeography.geographical_feature_category060102 archaeologyRange (biology)SteppePastoralismGlacier06 humanities and the artsengineering.materialArchaeology03 medical and health sciencesAncient DNABaltic seaengineering0601 history and archaeologyBronzeMesolithic030304 developmental biology
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Ancient DNA reveals prehistoric gene-flow from Siberia in the complex human population history of North East Europe.

2013

North East Europe harbors a high diversity of cultures and languages, suggesting a complex genetic history. Archaeological, anthropological, and genetic research has revealed a series of influences from Western and Eastern Eurasia in the past. While genetic data from modern-day populations is commonly used to make inferences about their origins and past migrations, ancient DNA provides a powerful test of such hypotheses by giving a snapshot of the past genetic diversity. In order to better understand the dynamics that have shaped the gene pool of North East Europeans, we generated and analyzed 34 mitochondrial genotypes from the skeletal remains of three archaeological sites in northwest Ru…

Gene Flow0106 biological sciencesCancer Researchlcsh:QH426-470GenotypePopulation DynamicsPopulationPopulation ModelingScandinavian and Nordic CountriesBiologySocial and Behavioral SciencesDNA Mitochondrial010603 evolutionary biology01 natural sciencesWhite PeopleHaplogroupRussiaCoalescent theory03 medical and health sciencesGeneticsHumanseducationBiologyMolecular BiologyGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyEvolutionary Biology0303 health scienceseducation.field_of_studyGenetic diversityPopulation BiologyGenetic VariationPaleogeneticsEuropeSiberialcsh:GeneticsBiological AnthropologyGenetics PopulationAncient DNAArchaeologyHaplotypesEvolutionary biologyAnthropologyGenome MitochondrialGene poolPopulation GeneticsResearch ArticleHuman mitochondrial DNA haplogroup
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Ancient human genomes suggest three ancestral populations for present-day Europeans

2014

We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes1,2,3,4 with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians3, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these popula…

HistoryNeanderthalBiologíaPopulation DynamicsPresent dayGenoma humàGenome//purl.org/becyt/ford/1 [https]Basal (phylogenetics)Settore BIO/13 - Biologia ApplicataHistory AncientGeneticsPrincipal Component Analysiseducation.field_of_study0303 health sciencesGenomeMultidisciplinaryAncient DNA030305 genetics & heredityfood and beveragesAgricultureGenomics3. Good healthEuropeWorkforceCIENCIAS NATURALES Y EXACTASHumanArchaeogeneticsAsiaLineage (genetic)EUROPEOtras Ciencias BiológicasEuropean Continental Ancestry GroupPopulationSettore BIO/08 - ANTROPOLOGIAevolution; EuropeansGenomicsBiologyArticleWhite PeopleAncientGenètica de poblacions humanesHuman originsCiencias Biológicas03 medical and health sciencesHUMAN ORIGINSbiology.animalHumansANCIENT DNA//purl.org/becyt/ford/1.6 [https]educationQuantitative Biology - Populations and EvolutionDenisovan030304 developmental biologyGenetic diversityancient DNA modern DNA Europeans prehistoryGenome HumanPopulations and Evolution (q-bio.PE)biology.organism_classificationAncient DNAEvolutionary biologyFOS: Biological sciencesUpper PaleolithicHuman genomeGENOMICS
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