0000000000356806

AUTHOR

Eduardo Carmona Ballestero

Ten millennia of hepatitis B virus evolution

Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd…

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Antiguas noticias, nuevas interpretaciones: la ocupación campaniforme del Cerro del Castillo de Burgos

El trabajo centra su interes en el registro arqueologico prehistorico procedente del Cerro del Castillo de Burgos. La informacion procede de la excavacion llevada cabo a mediados de los anos 80 por el equipo dirigido por Jose Luis Uribarri. En ella se documentaron evidencias campaniformes en el estrato mas antiguo de una secuencia fundamentalmente protohistorica (nivel XII). Su presencia dio pie a interpretar tal estrato como un �nivel de ocupacion� campaniforme. Una revision de los materiales arqueologicos efectuada por el firmante mostraba discrepancias respecto de las consideraciones expresadas por el equipo de excavacion. Puesto que el registro del Cerro del Castillo ha sido utilizado h…

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The maternal genetic make-up of the Iberian Peninsula between the Neolithic and the Early Bronze Age

Agriculture first reached the Iberian Peninsula around 5700 BCE. However, little is known about the genetic structure and changes of prehistoric populations in different geographic areas of Iberia. In our study, we focus on the maternal genetic makeup of the Neolithic (~ 5500–3000 BCE), Chalcolithic (~ 3000–2200 BCE) and Early Bronze Age (~ 2200–1500 BCE). We report ancient mitochondrial DNA results of 213 individuals (151 HVS-I sequences) from the northeast, central, southeast and southwest regions and thus on the largest archaeogenetic dataset from the Peninsula to date. Similar to other parts of Europe, we observe a discontinuity between hunter-gatherers and the first farmers of the Neol…

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