0000000000356875

AUTHOR

Philipp W. Stockhammer

showing 7 related works from this author

Ten millennia of hepatitis B virus evolution

2021

Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd…

Phylogeographic historyHepatitis B/history01 natural sciencesThe RepublicCommunicable Diseases EmergingGermanCommunicable Diseases Emerging/historyAgency (sociology)Science and technologyComputingMilieux_MISCELLANEOUSHistory AncientPhylogenymedia_common0303 health sciencesMultidisciplinaryAncient DNAEuropean researchvirus diseasesGenomicsHepatitis B3. Good healthEuropelanguageComputingMethodologies_DOCUMENTANDTEXTPROCESSINGChristian ministryPaleogenomic analysesAsian Continental Ancestry Group010506 paleontologyHepatitis B virusAsiaHepatitis B virus/classificationEuropean Continental Ancestry GroupLibrary scienceBiología CelularWhite PeopleMarie curieEvolution Molecular03 medical and health sciencesAmerican NativesAsian PeoplePolitical scienceGenomic datamedia_common.cataloged_instanceHumansSlovakEuropean unionAmerican Indian or Alaska Native030304 developmental biology0105 earth and related environmental sciencesGenetic VariationPaleontologyPrehistoriaA300language.human_languagedigestive system diseasesAmerican natives; Americas; Asia; Asian continental ancestry group; Communicable diseases Emerging; Europe; European continental ancestry group; Evolution molecular; Genetic variation; Genomics; Hepatitis B; Hepatitis B virus; History Ancient; Humans; Paleontology; PhylogenyAmericas
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Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-path Neolithic expansion to Western Europe

2021

Uniparentally-inherited markers on mitochondrial DNA (mtDNA) and the non-recombining regions of the Y chromosome (NRY), have been used for the past 30 years to investigate the history of humans from a maternal and paternal perspective. Researchers have preferred mtDNA due to its abundance in the cells, and comparatively high substitution rate. Conversely, the NRY is less susceptible to back mutations and saturation, and is potentially more informative than mtDNA owing to its longer sequence length. However, due to comparatively poor NRY coverage via shotgun sequencing, and the relatively low and biased representation of Y-chromosome variants on capture assays such as the 1240 k, ancient DNA…

CzechSELECTIONPopulation geneticsMITOCHONDRIAL-DNAearly farmersDIVERSITYmitochondrial DNAshotgun sequencingPrehistòriaHaplogroupGerman0302 clinical medicineMedicine and Health SciencesDNA sequencingScience and technologymedia_common0303 health sciencesMultidisciplinaryHorizon (archaeology)Critical eventShotgun sequencingchromosomal haplogroupsEuropean researchQRSTEPPEWestern europelanguageMedicineGenetic MarkersMitochondrial DNA[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistoryuniparentally-inherited markersScienceLibrary scienceBiologyY chromosomeDNA MitochondrialPolymorphism Single NucleotideTarget enrichmentArticle03 medical and health sciencesPolitical scienceHumansmedia_common.cataloged_instanceANCIENT DNAGenetic TestingEuropean unionAlleles030304 developmental biologyMUTATION-RATEChromosomes Human YY chromosomeSaturation (genetic)History and ArchaeologyY-mappable capture assayAncient DNA; Neanderthals; Anatomically modern humanslanguage.human_languageNeolithic transitionGenetics PopulationAncient DNAHaplotypesEvolutionary biologyGENOMIC HISTORY030217 neurology & neurosurgery
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The beaker phenomenon and the Genomic transformations of Northwest Europe

2018

Bell Beaker pottery spread across western and central Europe beginning around 2750 BCE before disappearing between 2200–1800 BCE. The mechanism of its expansion is a topic of long-standing debate, with support for both cultural diffusion and human migration. We present new genome-wide ancient DNA data from 170 Neolithic, Copper Age and Bronze Age Europeans, including 100 Beaker-associated individuals. In contrast to the Corded Ware Complex, which has previously been identified as arriving in central Europe following migration from the east, we observe limited genetic affinity between Iberian and central European Beaker Complex-associated individuals, and thus exclude migration as a signific…

Male0301 basic medicineSteppeADNNéolithiqueBell BeakerArqueologiaBell Beaker culturegenome wide ancient DNA0302 clinical medicineArchéologiePhenomenonddc:5500601 history and archaeologySuisseHistory Ancient0303 health scienceseducation.field_of_studygeography.geographical_feature_categoryMultidisciplinary060102 archaeology[SDE.IE]Environmental Sciences/Environmental EngineeringHuman migrationPréhistoireNeolithic periodGene PoolGenomics[SHS.GEO]Humanities and Social Sciences/Geography06 humanities and the artsbell BeakerEuropeGeographyArchaeologyCeràmicaEthnologyMégalithisme1000ArchaeogeneticsCampaniformePotteryHuman Migration[SDE.MCG]Environmental Sciences/Global ChangesPopulationAncient historyArticle03 medical and health sciencesSpatio-Temporal Analysispopular geneticsBronze AgeBeakerCultural EvolutionNeolíticgenomicsHumansDNA Ancienteducation030304 developmental biologyChromosomes Human YGenome Humanbusiness.industryNorthwest Europebell Beaker; genome wide ancient DNA; EuropeChalcolithic[SDE.ES]Environmental Sciences/Environmental and SocietyAncient DNAGenetics Population030104 developmental biologyHaplotypesPeriod (geology)GenomicPottery[SDE.BE]Environmental Sciences/Biodiversity and Ecologybusiness030217 neurology & neurosurgery
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Exotic foods reveal contact between South Asia and the Near East during the second millennium BCE

2020

Aunque el papel clave del comercio a larga distancia en la transformación de las cocinas en todo el mundo está bien documentado desde al menos la época romana, la prehistoria del comercio de alimentos euroasiático es menos visible. Con el fin de arrojar luz sobre la transformación de las cocinas del Mediterráneo oriental durante la Edad del Bronce y la Edad del Hierro Temprana, analizamos los microrestos y las proteínas conservadas en el cálculo dental de individuos que vivieron durante el segundo milenio a. Nuestros resultados proporcionan evidencia clara del consumo de alimentos básicos esperados, como cereales (Triticeae), sésamo ( Sesamum ) y dátiles ( Phoenix ). Además, informamos evid…

Mediterranean climateAsiaSouthern LevantDried fruitHuman MigrationSocial Sciences930Ancient historyDNA MitochondrialPrehistoryAlte Geschichte Vor- und Frühgeschichte ArchäologieMiddle EastAsian PeopleBronze AgeOther parts of ancient world (Antiquity) [R939]HumansDental CalculusHistory AncientMultidisciplinaryMiddle EastFossilsGenome HumanHistory of the ancient world to ca. 499 [T930]Restes de plantes (Arqueologia)CommercePrehistoric Archaeology [FVFG]Spice tradeGeographyArchaeologyFoodIron AgeGreece (Antiquity) [R938]Food Analysis
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Female exogamy and gene pool diversification at the transition from the final neolithic to the early Bronze Age in central Europe

2017

Human mobility has been vigorously debated as a key factor for the spread of bronze technology and profound changes in burial practices as well as material culture in central Europe at the transition from the Neolithic to the Bronze Age. However, the relevance of individual residential changes and their importance among specific age and sex groups are still poorly understood. Here, we present ancient DNA analysis, stable isotope data of oxygen, and radiogenic isotope ratios of strontium for 84 radiocarbon-dated skeletons from seven archaeological sites of the Late Neolithic Bell Beaker Complex and the Early Bronze Age from the Lech River valley in southern Bavaria, Germany. Complete mitocho…

Male0301 basic medicineengineering.materialDiversification (marketing strategy)03 medical and health sciencesBronze AgeBeakerKinshipHumans0601 history and archaeologyBronzeAnthropology CulturalHistory AncientMultidisciplinary060102 archaeologyExogamyGene Pool06 humanities and the artsBiological SciencesArchaeologyEurope030104 developmental biologyAncient DNAGeographyGenome MitochondrialengineeringFemaleGene pool
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New insights into Early Celtic consumption practices: Organic residue analyses of local and imported pottery from Vix-Mont Lassois

2019

The rich Mediterranean imports found in Early Celtic princely sites (7th-5th cent. BC) in Southwestern Germany, Switzerland and Eastern France have long been the focus of archaeological and public interest. Consumption practices, particularly in the context of feasting, played a major role in Early Celtic life and imported ceramic vessels have consequently been interpreted as an attempt by the elite to imitate Mediterranean wine feasting. Here we present the first scientific study carried out to elucidate the use of Mediterranean imports in Early Celtic Central Europe and their local ceramic counterparts through organic residue analyses of 99 vessels from Vix-Mont Lassois, a key Early Celti…

Mediterranean climate10108 Institute of ArchaeologyCeramicsWineBiochemistryAgricultural economicsFatsAnimal ProductsGermanyMedicine and Health SciencesBeeswaxVitis0601 history and archaeologyMaterials0303 health sciencesMultidisciplinaryGreece060102 archaeologyAlcoholic BeveragesQREukaryotafood and beveragesAgriculture06 humanities and the artsPlantsLipidsEuropeGeographyArchaeologyPhysical SciencesMedicineFranceOrganic Materials900 HistorySwitzerlandResearch ArticleMilletCeltic languagesScienceMaterials Science1100 General Agricultural and Biological SciencesBeverages03 medical and health sciences1300 General Biochemistry Genetics and Molecular BiologyAnimalsHumansPlant OilsGrassesMilletsNutrition030304 developmental biologyWineBeehive1000 Multidisciplinary[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and PrehistoryConsumption practicesOrganismsBiology and Life SciencesFeeding BehaviorDietWaxesGrape winePotteryEdible GrainOilsScientific studyPLOS ONE
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The genomic history of Southern Europe

2018

Farming was first introduced to southeastern Europe in the mid-7th millennium BCE - brought by migrants from Anatolia who settled in the region before spreading throughout Europe. However, the dynamics of the interaction between the first farmers and the indigenous hunter-gatherers remain poorly understood because of the near absence of ancient DNA from the region. We report new genome-wide ancient DNA data from 204 individuals-65 Paleolithic and Mesolithic, 93 Neolithic, and 46 Copper, Bronze and Iron Age-who lived in southeastern Europe and surrounding regions between about 12,000 and 500 BCE. We document that the hunter-gatherer populations of southeastern Europe, the Baltic, and the Nor…

0301 basic medicineMaleHistorySteppe01 natural sciencesgenome wide ancient DNA0302 clinical medicinepopulation dynamicsComputingMilieux_MISCELLANEOUSHistory Ancient2. Zero hunger0303 health scienceseducation.field_of_studyMultidisciplinarygeography.geographical_feature_categoryFarmersGenomeAgricultureCline (biology)GenomicsGrasslandEuropeGeographyWestern europeEthnologyFemalesoutheastern EuropeHumanArchaeogenetics010506 paleontologyAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryHuman MigrationPopulationPopulationSettore BIO/08 - AntropologiaIndigenousArticleAncient03 medical and health sciencesgenetic variation ; genomics ; prehistoric Europe ; prehistoric archeology ; bioarchaeologyBioarchaeologygenomicsGeneticsHumansHUMANISTIC SCIENCES. Archeology.FarmerDNA AncientSex DistributioneducationMesolithic030304 developmental biology0105 earth and related environmental sciencesHUMANISTIČKE ZNANOSTI. Arheologija.Extramuralbusiness.industryGenome HumanAmbientaleDNAArchaeologyPRIRODNE ZNANOSTI. Biologija. Genetika evolucija i filogenija.genome wide ancient DNA; southeastern Europe; population dynamics030104 developmental biologyAncient DNAGenetics PopulationAgriculturegenetic variationAgriculture; Asia; DNA Ancient; Europe; Farmers; Female; Genetics Population; Genome Human; Grassland; History Ancient; Human Migration; Humans; Male; Sex Distribution; GenomicsAncient DNA Genomics Southeastern Europe Genetic VariationbusinessNATURAL SCIENCES. Biology. Genetics Evolution and Phylogenetics.030217 neurology & neurosurgery
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