Evaluation of Hemodynamic Parameters for Adaptive Control of the Artificial Heart by Simulation of the Vascular System

Abstract A nonlinear dynamic mathematical model of the cardiovascular system is outlined, which is employable to analyse the hemodynamic system behaviour under normal as well as under pathological conditions. By modifying this model, assuming that cardiac output is constant at a preset level (which is in accordance with most of the total artificial heart systems, since their pumps output is preselected with fixed driving parameters), the hemodynamic behaviour of a circulation system with an artificial heart was simulated. Comparing the simulation results with those obtained from total artificial heart experiments, a good agreement in right atrial and aortic pressure under exercise condition…