0000000000371389

AUTHOR

Jesus M. Santiago

showing 2 related works from this author

HLA-DQ: Celiac diseasevsinflammatory bowel disease

2018

Aim To determine the genetic predisposition to celiac disease (CeD) in inflammatory bowel disease (IBD) patients by quantifying the frequency of CeD-related human leucocyte antigen (HLA) (HLA-CeD: HLA-DQ2 and -DQ8) in IBD patients globally, by type of IBD and gender, and by calculating the protective/risk contribution of these haplotypes in the development of the IBD disease. Methods We conducted a prospective study with IBD patients from our Unit. Clinical information was gathered and blood was tested for HLA-CeD. The control group was made up of unrelated Valencian organ donors. Results 1034 subjects were analyzed: 457 IBD [207 ulcerative coliti (UC) and 250 Crohn's disease (CD)] patients…

medicine.medical_specialtyCrohn's diseaseHLA-DQB1business.industryGastroenterologynutritional and metabolic diseasesGeneral MedicineHuman leukocyte antigenmedicine.diseaseGastroenterologyInflammatory bowel diseaseUlcerative colitis03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisInternal medicineHLA-DQGenetic predispositionMedicine030211 gastroenterology & hepatologybusinessProspective cohort studyWorld Journal of Gastroenterology
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DATOS CLÍNICOS NO INVASIVOS RELACIONADOS CON LA MORTALIDAD DE PACIENTES CON INGESTA DE CÁUSTICOS

2009

Introduccion La mortalidad inmediata en la ingesta causticos se relaciona con la intensidad de las lesiones esofagogastricas; ocasionalmente no es factible realizar endoscopia por malas condiciones clinicas del paciente/negativa de este/no disponibilidad de la tecnica; en esta situacion la valoracion de la gravedad del paciente y posible evolucion fatal se debe realizar mediante datos clinicos y analiticos. Objetivos Identificar los datos clinicos relacionados con la mortalidad de pacientes con ingesta de causticos. Material y metodos Estudio prospectivo protocolizado (1995–2008) incluyendo datos demograficos, clinicos, analiticos, endoscopicos y evolutivos sobre 242 pacientes (107 hombres …

Gynecologymedicine.medical_specialtyHepatologybusiness.industryGastroenterologymedicinebusinessGastroenterología y Hepatología
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