0000000000373021

AUTHOR

Flavio Fusco

showing 7 related works from this author

Palliative sedation in advanced cancer patients followed at home: A retrospective analysis

2012

Abstract CONTEXT: Data regarding palliative sedation at home in dying patients are lacking. OBJECTIVES: To describe the frequency, indication, and modality of palliative sedation (PS) in patients followed at home. METHODS: A retrospective analysis of home care cancer patients was performed. Patients who received PS before dying were selected and information about epidemiologic characteristics, indications, duration, drugs, and outcomes was collected. RESULTS: Of 370 medical charts of patients who died at home, 49 patients received PS before dying. PS was proposed by the team, relatives, or both in 63.3%, 4.1%, and 32.6% of cases, respectively. Delirium alone or in combination with other sym…

end of lifeMalePediatricsmedicine.medical_specialtyPalliative carePainComorbiditySettore MED/42 - Igiene Generale E ApplicataPalliative sedationadvanced cancer patientPalliative sedationRisk FactorsNeoplasmsRETROSPECTIVE STUDYPrevalenceMedicineHumansHypnotics and SedativesPALLIATIVE SEDATION; advanced cancer patients; RETROSPECTIVE STUDYIntensive care medicineSurvival rateGeneral NursingSurvival analysisNursing (all)2901 Nursing (miscellaneous)Retrospective StudiesTerminal Carepalliative carebusiness.industryDeliriumRetrospective cohort studymedicine.diseaseComorbidityHome Care ServicesSurvival AnalysisSurvival RateTreatment OutcomeAnesthesiology and Pain MedicineItalyend of life; home care; palliative care; Palliative sedation; Comorbidity; Delirium; Female; Home Care Services; Humans; Hypnotics and Sedatives; Italy; Male; Neoplasms; Pain; Palliative Care; Prevalence; Retrospective Studies; Risk Factors; Survival Analysis; Survival Rate; Terminal Care; Treatment Outcome; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)MidazolamDeliriumFemaleNeurology (clinical)medicine.symptombusinesshome caremedicine.drug
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Breakthrough Pain in Advanced Cancer Patients Followed at Home: A Longitudinal Study

2009

The aim of this study was to longitudinally assess breakthrough pain (BP) in advanced cancer patients who were admitted to home palliative care. One hundred and one consecutive patients who were admitted to one of the two home care programs and were representative of the cancer population followed at home in Italy were included. Patients were excluded only if at admission they were cognitively impaired or too unwell to provide reliable answers to questions regarding data collection. At admission (T(0)), and one month later (T(1)), data were recorded about the pharmacological treatment of background pain and its effectiveness; the presence of BP and its intensity, duration, and number of epi…

Malemedicine.medical_specialtyPalliative careAnalgesicPopulationPainComorbidityRisk AssessmentMedication prescriptionadvanced cancer patientRisk FactorsNeoplasmsInternal medicineBreakthrough painmedicineHumansLongitudinal StudieseducationSurvival rateGeneral NursingAgededucation.field_of_studybusiness.industryIncidenceIncidence (epidemiology)longitudinal studymedicine.diseaseHome Care ServicesSurvival AnalysisComorbiditySurvival RateAnesthesiology and Pain MedicineItalyPhysical therapyFemaleNeurology (clinical)businessCancer painJournal of Pain and Symptom Management
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Opioid switching in patients with advanced cancer followed at home. A retrospective analysis.

2013

Abstract CONTEXT: Opioid switching has been found to improve opioid responsiveness in different conditions. However, data on opioid switching performed at home are almost nonexistent, despite the fact that most patients are followed at home. OBJECTIVES: The aim of this retrospective survey was to determine frequency, indications, usefulness, and safety of opioid switching when treating advanced cancer-related pain in patients followed at home. METHODS: A retrospective review of data from patients with advanced cancer followed at home by three home care teams for a period of two years was performed. Patients who had their opioids switched were selected. Reasons for switching opioid doses and…

Maleretrospective studyComorbiditySettore MED/42 - Igiene Generale E Applicataadvanced cancer patientNeoplasmsRetrospective analysisPrevalenceOpioid switching; advanced cancer patients; retrospective studyCancer painProspective cohort studyNursing (all)2901 Nursing (miscellaneous)General NursingAnalgesicsDrug SubstitutionHome Care ServicesAnalgesics OpioidCausalitySurvival RateTreatment OutcomeItalyFemaleDrugmedicine.drugmedicine.medical_specialtyAnalgesicPainContext (language use)OpioidDose-Response RelationshipmedicineHumansIn patientIntensive care medicineAgedRetrospective StudiesDose-Response Relationship Drugbusiness.industryAdvanced cancerSurvival AnalysisCancer pain; home care; opioid switching; Aged; Analgesics Opioid; Causality; Comorbidity; Dose-Response Relationship Drug; Drug Substitution; Female; Home Care Services; Humans; Italy; Male; Neoplasms; Pain; Prevalence; Quality of Life; Retrospective Studies; Survival Analysis; Survival Rate; Treatment Outcome; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)Anesthesiology and Pain MedicineOpioidEmergency medicineMorphineOpioid switchingQuality of LifeNeurology (clinical)home carebusinessJournal of pain and symptom management
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Factors involved in gastrointestinal bleeding in advanced cancer patients followed at home

2003

Abstract There is a lack of information on the frequency of symptomatic gastrointestinal bleeding in patients with advanced cancer. This group of patients presents several risk factors for developing gastrointestinal bleeding. The aim of this multicenter longitudinal survey was to assess the frequency of gastrointestinal bleeding and possible factors implicated in advanced cancer patients followed at home. A consecutive sample of 439 patients who referred to home palliative care program entered the study. Age, gender, primary cancer and known metastases, possible associated pathologies, history of peptic disease, use of previous or actual nonsteroidal anti-inflammatory drugs (NSAIDs) and st…

Malemedicine.medical_specialtyGastrointestinal bleedingPalliative careBlood transfusionAnemiamedicine.medical_treatmentgastrointestinal bleedingSettore MED/42 - Igiene Generale E ApplicataGastroenterologyadvanced cancer patientGastrointestinal AgentsRisk FactorsMelenaNeoplasmsInternal medicinemedicineHumansLongitudinal StudiesProspective StudiesProspective cohort studybusiness.industryAnti-Inflammatory Agents Non-SteroidalPalliative CareCancermedicine.diseaseHome Care ServicesAdvanced cancerhome palliative careOncologyFemaleSteroidsmedicine.symptomGastrointestinal HemorrhagebusinessFollow-Up StudiesSupportive Care in Cancer
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Palliative sedation in patients with advanced cancer followed at home: A systematic review

2011

Abstract Context Patients with advanced cancer who are near the end of life may experience intolerable suffering refractory to targeted palliative therapies. Palliative sedation (PS) is considered to be an effective treatment modality for these refractory symptoms when aggressive efforts fail to provide relief. Objectives The aim of this study was to systematically review articles regarding PS performed at home in patients with intractable symptoms. Methods Literature databases searched included MedLine, PubMed, and EMBASE. The text words and MeSH/EMTREE terms "home care" and "sedation" were used for electronic database searches. Results Six articles met the inclusion criteria for research …

end of lifemedicine.medical_specialtyPalliative careSedationMEDLINEPainContext (language use)Palliative sedationend of life; home care; Palliative sedation; Clinical Trials as Topic; Delirium; Dyspnea; Home Care Services; Humans; Hypnotics and Sedatives; Neoplasms; Pain; Retrospective Studies; Treatment Outcome; Palliative Care; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)NeoplasmsmedicineHumansHypnotics and SedativesIntensive care medicineProspective cohort studyGeneral NursingNursing (all)2901 Nursing (miscellaneous)Retrospective StudiesClinical Trials as Topicbusiness.industryPalliative CareDeliriumRetrospective cohort studyHome Care ServicesDyspneaTreatment OutcomeAnesthesiology and Pain MedicineMeta-analysisMidazolamNeurology (clinical)medicine.symptombusinesshome caremedicine.drug
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Orphan symptoms in advanced cancer patients followed at home

2013

Abstract Orphan symptoms are rarely assessed, particularly at home. The aim of this multicenter prospective study was to assess the prevalence of these symptoms and eventual factors possibly associated in advanced cancer patients at admission of a home care program. A prospective study was performed at three home care programs in Italy. Patients' data were collected, including age, sex, diagnosis, and Karnofsky status. Possible contributing factors were analyzed; preexisting neurological diseases, cerebral metastases, hyperthermia, diabetes, a state of dehydration clinically evident and/or oliguria, possible biochemical parameters when available, data regarding recent chemotherapy, opioids …

MyoclonusMalemedicine.medical_specialtyPalliative careHiccup; Home care; Myoclonus; Palliative care; Pruritus; Sweating; Tenesmus; Aged; Analgesics Opioid; Female; Fentanyl; Hiccup; Home Care Services; Hospitalization; Humans; Italy; Karnofsky Performance Status; Male; Myoclonus; Neoplasms; Prospective Studies; Pruritus; Sweating; Oncology; Medicine (all)Hiccup; Home care; Myoclonus; Palliative care; Pruritus; Sweating; TenesmusSweatingOpioidSettore MED/42 - Igiene Generale E ApplicataHome careFentanylHiccupPrurituOliguriaInternal medicineDiabetes mellitusNeoplasmsMedicineHumansVesical tenesmusProspective StudiesKarnofsky Performance StatusProspective cohort studyAgedAnalgesicsbusiness.industryPruritusMedicine (all)Tenesmusmedicine.diseaseHome Care ServicesAnalgesics OpioidFentanylHospitalizationDistressItalyOncologyAnesthesiaPalliative careFemalemedicine.symptombusinessMyoclonusMyoclonumedicine.drug
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Epidemiology and Characteristics of Episodic Breathlessness in Advanced Cancer Patients. An Observational Study

2016

Abstract Context Episodic breathlessness is a relevant aspect in patients with advanced cancer. Objectives The aim of this study was to assess the different aspects of this clinical phenomenon. Methods A consecutive sample of patients with advanced cancer admitted to different settings for a period of six months was surveyed. The presence of background breathlessness and episodic breathlessness, their intensity (numerical scale 0–10), and drugs used for treatment were collected. Factors inducing episodic breathlessness and its influence on daily activities were investigated. Results Of 921 patients, 29.3% ( n  = 269) had breathlessness and 134 patients (49.8%) were receiving drugs for backg…

MalePediatricsmedicine.medical_specialtyPalliative careActivities of daily livingTime FactorsEpisodic breathlessneSettore MED/41 - AnestesiologiaContext (language use)advanced cancer; dyspnea; Episodic breathlessness; opioids; palliative care; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)DiseaseComorbidityepisodic breathlessness; advanced cancer; dyspnea; opioids; palliative care03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineNeoplasmsEpidemiologyActivities of Daily LivingmedicinePrevalenceHumansadvanced cancer030212 general & internal medicineKarnofsky Performance StatusGeneral NursingNursing (all)2901 Nursing (miscellaneous)Agedpalliative careEpisodic breathlessnessbusiness.industryEpisodic breathlessness; advanced cancer; dyspnea; opioids; palliative careopioidsCardiovascular Agentsrespiratory systemMiddle Ageddyspneamedicine.diseaseComorbidityAnesthesiology and Pain Medicine030220 oncology & carcinogenesisCardiovascular agentMultivariate AnalysisopioidObservational studyFemaleNeurology (clinical)business
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