0000000000385185
AUTHOR
Cheerfulman Masharing
Self-assembly of extended Schiff base amino acetate skeletons, 2-{[(2Z)-(3-hydroxy-1-methyl-2-butenylidene)]amino}phenylpropionate and 2-{[(E)-1-(2-hydroxyaryl)alkylidene]amino}phenylpropionate skeletons incorporating organotin(IV) moieties: Synthesis, spectroscopic characterization, crystal structures, and in vitro cytotoxic activity
The organotin(IV) compounds, [Ph 3 SnL 1 H] n · nCCl 4 ( 1 ), [Me 2 SnL 2 (OH 2 )] ( 2 ), [ n Bu 2 SnL 2 ] ( 3 ), [Ph 2 SnL 2 ] n ( 4 ), [Ph 3 SnL 2 H] n ( 5 ) and [Ph 3 SnL 3 H] n ( 7 ) (L 1 = 2-{[(2 Z )-(3-hydroxy-1-methyl-2-butenylidene)]amino}phenylpropionate and L 2−3 = 2-{[( E )-1-(2-hydroxyaryl)alkylidene]amino}phenylpropionate), were synthesized by treating the appropriate organotin(IV) chloride(s) with the potassium salt of the ligand in a suitable solvent, while [ n Bu 2 SnL 3 (OH 2 )] ( 6 ) was obtained by reacting the acid form of L 3 (generated in situ) with n Bu 2 SnO. These complexes have been characterized by 1 H, 13 C, 119 Sn NMR, ESI-MS, IR and 119m Sn Mossbauer spectro…
Synthesis and characterization of trbenzyltin(IV) and dibenzyltin(IV) complexes of 2-((2Z)-3-hydroxy-1-methyl-2-butenylidene)amino)acetic acid: Crystal structure of tribenzyl(2-(2Z)-3-hydroxy-1-methyl-2-butenylidene)amino)acetato)tin(IV).
Reactions of equimolar quantities of potassium 2-{[(2Z)-3-hydroxy-1-methyl-2-butenylidene]amino}acetate, with R n SnX4−n (R: benzyl– and n=2 or 3) in methanol yielded products of compositions LHSn(PhCH2)3 and LSn(PhCH2)2, respectively. The complexes were characterized by microanalysis, IR, NMR (1H, 13C, 119Sn) and 119mSn Mossbauer spectroscopy. A full characterization of the structure of the complex, tribenzyl{2-{[(2Z)-3-hydroxy-1-methyl-2-butenylidene]amino}acetato}tin(IV), was carried out by single crystal X-ray crystallography. The compound exists as centrosymmetric dimers in which two ligand molecules bridge the two tin centres. Each of the tin atoms in the dimeric unit is five coordina…
Synthesis and Structures of Two Triorganotin(IV) Polymers R3Sn{O2CC6H4[N=C(H)}{C(CH3)CH(CH3)-3-OH]-p} n (R = Me and Ph) Containing a 4-[(2Z)-(3-Hydroxy-1-methyl-2-butenylidene)amino] benzoic Acid Framework
Two new polymeric triorganotin(IV) complexes R3Sn{O2CC6H4[N=C(H)}{C(CH3)CH(CH3)-3-OH]-p} n ([Me3Sn(LH)] n : 1) and ([Ph3Sn(LH)] n : 2) containing a 4-[(2Z)-(3-hydroxy-1-methyl-2-butenylidene)amino]benzoate (LH) framework were prepared. Both compounds have been characterized by 1H, 13C, 119Sn NMR, IR and 119Sn Mossbauer spectroscopic techniques in combination with elemental analyses. The crystal structures of complexes 1 and 2 reveal that they exist as polymeric zig-zag chains in which the LH-bridged Sn-atoms adopt a trans-R3SnO2 trigonal bipyramidal configuration with R groups in the equatorial positions and the axial sites occupied by an oxygen atom from the carboxylate ligand and the alco…
Synthesis and characterization of some diorganotin(IV) complexes of Schiff bases derived from a non-protein amino acid. Crystal structures of {HO2CC6H4[NC(H)}{C(CH3)CH(CH3)-3-OH]-p} and its di-n-butyltin(IV) complex (nBu2Sn{O2CC6H4[NC(H)}{C(CH3)CH(CH3)-3-OH]-p}2)
Diorganotin(IV) complexes R2Sn(LH)2 (R = Me, nBu) and {[nBu2Sn(LH)]2O}2 (LH = 4-[(2Z)-(3-hydroxy-1-methyl-2-butenylidene)amino]benzoate and 4-[{(E)-1-(2-hydroxyphenyl)methylidene}mino]benzoate) have been reported. The complexes were characterized by elemental analysis, IR, NMR (1H, 13C, 119Sn) and 119mSn Mossbauer spectroscopy. Crystal structures of a ligand {HO2CC6H4[NC(H)}{C(CH3)CH(CH3)-3-OH]-p} and one of its di-n-butyltin(IV) complexes (nBu2Sn{O2CC6H4[NC(H)}{C(CH3)CH(CH3)-3-OH]-p}2) were determined. The spectroscopic data suggest that R2Sn(LH)2 complexes have skew-trapezoidal bipyramidal structure while {[nBu2Sn(LH)]2O}2 complexes adopt a dimeric tetraorganodistannoxane structure in the…
Synthesis, characterization, cytotoxic activity and crystal structures of tri- and di-organotin(IV) complexes constructed from the β-{[(E)-1-(2-hydroxyaryl)alkylidene]amino}propionate and β-{[(2Z)-(3-hydroxy-1-methyl-2-butenylidene)]amino}propionate skeletons
Abstract Reactions of potassium β-{[(E)-1-(2-hydroxyaryl)alkylidene]amino}propionates (L1HK-L3HK) and potassium β-{[(2Z)-(3-hydroxy-1-methyl-2- butenylidene)]amino}propionate (L4HK) with R3SnCl (R = Ph and nBu) and nBu2SnCl2 yielded complexes of composition Ph3SnL1H (1), Ph3SnL2H (2), Ph3SnL4H (3), nBu3SnL1H (4), and {[nBu2Sn(L2H)]2O}2 (5) and {[nBu2Sn(L3H)]2O}2 (6), respectively. These complexes have been characterized by 1H, 13C, 119Sn NMR, ESI-MS, IR and 119mSn Mossbauer spectroscopic techniques in combination with elemental analyses. The crystal structures of 1, 4, 5 and 6 were determined. In the solid state, compound 1 is a one-dimensional polymer built from SnPh3 moieties bridged by s…
Organotin(IV) complexes ofN-[(2Z)-3-hydroxy-1-methyl-2-butenylidene]glycine
Organotin(IV) derivatives of N-[(2Z)-3-hydroxy-1-methyl-2-butenylidene]glycine have been synthesized and characterized by 1H, 13C, 119Sn NMR, 119Sn Mossbauer, and IR spectroscopy along with elemental analyses. The di- and triorganotin(IV) complexes were readily obtained from the reactions of organotin halides and sodium/potassium N-[(2Z)-3-hydroxy-1-methyl-2-butenylidene]glycinate. The diorganotin compound reacted with Ph3SnCl in refluxing benzene to give the mixed organotin dinuclear complex of composition Ph2Sn(2-OC(CH3)-C(H)C(CH3)NCH2COO)·Ph3SnCl, which was characterized by single crystal X-ray structure determination. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:149–154, 2003; Publ…