0000000000389865

AUTHOR

Antonio Aguilar-salvatierra

showing 5 related works from this author

Jaw osteonecrosis management around a dental implant inserted 2 years before starting treatment with zoledronic acid

2015

Journal Article; Bisphosphonates (BP) are a type of drug known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and so bone resorption. BPs are widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw (ONJ). Zoledronic acid (ZA) is an intravenous BP used in the treatment and prophylaxis of bone disease in patients with malignant tumors with bone implication. ZA is the most potent BP in clinical development. This report describes the case of a 62-year-old woman with breast cancer antecedents which…

Peri-implantitisBone diseasemedicine.medical_treatmentDifosfonatosDentistryCase Report:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Peri-implantitisDental implant:Chemicals and Drugs::Organic Chemicals::Organophosphorus Compounds::Diphosphonates [Medical Subject Headings]Implantes dentales:Anatomy::Cells::Connective Tissue Cells::Macrophages::Osteoclasts [Medical Subject Headings]ImidazolesOsteonecrosisBisphosphonates:Diseases::Neoplasms [Medical Subject Headings]:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludNeoplasiasHumanosmedicine.anatomical_structureNeoplasias de la mama:Chemicals and Drugs::Biomedical and Dental Materials::Dental Materials::Dental Implants [Medical Subject Headings]UNESCO::CIENCIAS MÉDICASMaxillectomy:Diseases::Stomatognathic Diseases::Mouth Diseases::Peri-Implantitis [Medical Subject Headings]Oral SurgeryResorción óseamedicine.drugmedicine.medical_specialtyOdontología:Diseases::Musculoskeletal Diseases::Bone Diseases::Osteonecrosis [Medical Subject Headings]Bone resorptionBreast cancerOsteoclast:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Azoles::Imidazoles [Medical Subject Headings]medicinePeriimplantitisGeneral DentistryZoledronic acid:Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms [Medical Subject Headings]Osteonecrosis of the jawbusiness.industry:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Bone Remodeling::Bone Resorption [Medical Subject Headings]Osteoclastosmedicine.diseaseSurgeryZoledronic acid:Check Tags::Female [Medical Subject Headings]Osteonecrosis of the jawbusinessJournal of Clinical and Experimental Dentistry
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Effectiveness of a recent topical sialogogue in the management of drug-induced xerostomia

2011

Objectives: Use of certain drugs is the most common aetiology of xerostomia. Systemic sialogogues provide a longer effect than topic ones, but also induce relevant side effects. Topical sialogogues, as malic acid, allow a safe use as they induce no systemic side-effects or pharmacological interactions, being especially interesting in cases of mild hyposalivation and oral dryness, mainly the chronic use of xerostomizing drugs. The aim of this study was to evaluate the clinical effect of 1% malic acid in patients affected by xerostomia due to antihypertensives or antidepressants. Study Design: 10 patients with drug-induced xerostomia were prospectively evaluated before and after using malic a…

medicine.medical_specialtyDentistryOdontologíaDrug-induced xerostomiaGastroenterologylaw.inventionSubjective improvementchemistry.chemical_compoundRandomized controlled triallawInternal medicinemedicineIn patientSialogogueGeneral Dentistrybusiness.industry:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludstomatognathic diseaseschemistryUNESCO::CIENCIAS MÉDICASORAL DRYNESSEtiologyMalic acidbusinessJournal of Clinical and Experimental Dentistry
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Bisphosphonates, vitamin D, parathyroid hormone, and osteonecrosis of the jaw. Could there be a missing link?

2016

It is estimated that over 190 million bisphosphonates have been prescribed worldwide. But this drug can produce adverse effects, of which osteonecrosis of the jaw and severe hypocalcemia are the most serious. It is evident that bisphosphonate administration affects multiple and diverse biochemical mediators related to bone metabolism. This review of literature investigates four basic parameters in patients treated with bisphosphonates - parathyroid hormone (PTH), bisphosphonates, vitamin D, calcium, and jaw osteonecrosis - which are fundamental for assessing bone metabolism and so the efficacy and correct use of the drug. The imbalances generated by vitamin D and calcium deficiencies, toget…

0301 basic medicineDrugmedicine.medical_specialtymedia_common.quotation_subjectmedicine.medical_treatmentParathyroid hormoneOdontologíaReviewBioinformaticsBone remodeling03 medical and health sciences0302 clinical medicineInternal medicineVitamin D and neurologyHumansMedicineVitamin DAdverse effectGeneral Dentistrymedia_commonBisphosphonate-associated osteonecrosis of the jawDiphosphonatesbusiness.industry030206 dentistryBisphosphonate:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la salud030104 developmental biologyEndocrinologyOtorhinolaryngologyParathyroid HormoneUNESCO::CIENCIAS MÉDICASBisphosphonate-Associated Osteonecrosis of the JawSurgeryOral SurgerybusinessOsteonecrosis of the jawMedicina Oral Patología Oral y Cirugia Bucal
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Evaluation of periimplant bone neoformation using different scanning electron microscope methods for measuring BIC. A dog study.

2012

Objetives: The aim of this study was to determine which of three methods for measuring BIC (bone-to-implant contact), using vestibular and lingual scanning electron microscopy (SEM) for different implant systems at 15, 30 and 90 days post-surgery was the most precise. An elemental analysis with SEM was used to evaluate neoformed bone composition for three implant systems at the same study times. Material and Methods: 36 implants were placed in eighteen Beagle dogs mandible about one year old and weighing approximately 12-13 kg in order to evaluate bone apposition to three different implant surfaces. It was used the third and fourth premolar and first molar distal sockets in both quadrants o…

MolarMaterials sciencebusiness.industryScanning electron microscopeMandibleH&E stainDentistryOdontología:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludApex (geometry)medicine.anatomical_structureTrichromeUNESCO::CIENCIAS MÉDICASPremolarmedicineImplantbusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
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Effectiveness of malic acid 1% in patients with xerostomia induced by antihypertensive drugs

2012

Objectives: Assessing the clinical effectiveness of a topical sialogogue on spray (malic acid, 1%) in the treatment of xerostomia induced by antihypertensive drugs. Study Design: This research has been carried out through a randomized double-blind clinical trial. 45 patients suffering from hypertensive drugs-induced xerostomia were divided into 2 groups: the first group (25 patients) received a topical sialogogue on spray (malic acid, 1%) whereas the second group (20 patients) received a placebo. Both of them were administered on demand for 2 weeks. Dry Mouth Questionnaire (DMQ) was used in order to evaluate xerostomia levels before and after product/placebo application. Unstimulated and st…

MaleSalivamedicine.medical_specialtyMalatesOdontologíaPlaceboDontostomatology for the Disabled or Special PatientsGastroenterologyXerostomialaw.inventionchemistry.chemical_compoundRandomized controlled trialDouble-Blind MethodlawInternal medicineSurveys and QuestionnairesmedicineHumansIn patientSialogogueGeneral DentistryAntihypertensive Agentsbusiness.industryMiddle AgedDry mouth:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludClinical trialEndocrinologyOtorhinolaryngologychemistryUNESCO::CIENCIAS MÉDICASSurgeryResearch-ArticleFemaleMalic acidmedicine.symptombusiness
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